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Indole-3-carbinol

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Identification
Molecular formula
C9H9NO
CAS number
700-06-1
IUPAC name
1H-indol-3-ylmethanol
State
State

At room temperature, Indole-3-carbinol is a solid.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.15
Boiling point (Celsius)
377.50
Boiling point (Kelvin)
650.70
General information
Molecular weight
147.17g/mol
Molar mass
147.1740g/mol
Density
1.2200g/cm3
Appearence

Indole-3-carbinol appears as a crystalline solid. It is typically a colorless to pale yellow powder or crystals, depending on its purity.

Comment on solubility

Solubility of 1H-indol-3-ylmethanol (C9H9NO)

1H-indol-3-ylmethanol is an organic compound known for its interesting solubility properties. This compound exhibits varying solubility depending on the solvent used and the conditions applied. Here are some key points to consider regarding its solubility:

  • Polar Solvents: 1H-indol-3-ylmethanol is expected to be soluble in polar solvents such as water, due to its hydroxyl (-OH) group, which can form hydrogen bonds.
  • Non-Polar Solvents: In non-polar solvents, solubility may be limited, as the hydrophobic indole ring could hinder interaction with non-polar molecules.
  • Temperature Influence: Increasing the temperature usually enhances solubility. Hence, dissolution in a polar solvent at elevated temperatures can yield better results.
  • pH Dependency: The solubility of 1H-indol-3-ylmethanol can also be affected by the pH of the solution, with more alkaline conditions potentially aiding its solubility due to deprotonation.

In summary, while 1H-indol-3-ylmethanol can be soluble in certain solvents, its solubility characteristics are influenced by various factors including polarity, temperature, and pH. Understanding these aspects is crucial for practical applications and research involving this compound.

Interesting facts

Interesting Facts about 1H-Indol-3-ylmethanol

1H-Indol-3-ylmethanol, often simply referred to as indol-3-ylmethanol, is a fascinating compound that has garnered the interest of chemists and biologists alike. Known for its unique structure, this compound belongs to the indole family, which is characterized by a bicyclic structure that consists of a benzene ring fused to a pyrrole ring.

Chemical Significance

  • Role in Biochemistry: 1H-indol-3-ylmethanol is recognized for its biological activity. It has been studied for its potential role in various physiological processes.
  • Precursor to Natural Products: This compound serves as a precursor for the synthesis of numerous natural products, including alkaloids that are crucial in medicinal chemistry.
  • Applications in Pharmaceuticals: Due to its indole structure, it has applications in the design of pharmaceutical compounds, especially those targeting neurological and tumor-related conditions.

Notable Characteristics

What makes this compound particularly interesting is its ability to interact with various biological systems. Here are a few notable characteristics:

  • Antioxidant Properties: There are studies suggesting that it possesses antioxidant properties, potentially helping to mitigate oxidative stress.
  • Neuroprotective Potential: Some research indicates that 1H-indol-3-ylmethanol may have neuroprotective effects, making it a compound of interest in neuropharmacology.
  • Isolation from Nature: Natural occurrences of this compound can be found in certain plants, illustrating the connection between organic chemistry and nature.

“The molecular diversity of compounds found in nature often leads to the discovery of new pharmacological agents.” This quote encapsulates the essence of exploring compounds like 1H-indol-3-ylmethanol. As research continues, who knows what new applications or properties may be discovered? The study of such compounds reminds us of the intricate connections between chemistry, biology, and medicine.

Synonyms
Indole-3-carbinol
700-06-1
3-Indolemethanol
INDOLE-3-METHANOL
(1H-Indol-3-yl)methanol
3-Hydroxymethylindole
1H-Indole-3-methanol
1H-indol-3-ylmethanol
3-Indolylcarbinol
Indinol
(1H-Indol-3-yl)-methanol
3-(Hydroxymethyl)indole
Indole 3 carbinol
Indole 3-carbinol
I3C
MFCD00005632
CCRIS 3261
3-Indolecarbinol
3-Indolylmethanol
EINECS 211-836-2
NSC 525801
NSC-525801
BRN 0121323
DTXSID7031458
UNII-C11E72455F
AI3-60090
C11E72455F
1~{H}-indol-3-ylmethanol
DTXCID5011458
CHEBI:24814
INDOLE-3-CARBINOL [VANDF]
5-21-03-00045 (Beilstein Handbook Reference)
INDOLE-3-CARBINOL [WHO-DD]
NCGC00090701-06
I0496
I3C cpd
SMR000385784
1H-Indol-3-Yl-Methanol
Prevention 4 (indole-3-carbinol)
I3C;3-Indolemethanol
methanol, indol-3-yl-
Spectrum2_001710
Spectrum3_001973
BSPBio_003573
MLS001333161
MLS001333162
SCHEMBL195520
SPECTRUM1505320
SPBio_001700
CHEMBL155625
1H-Indole-3-methanol (9CI)
GTPL10047
KBio3_002949
HMS1789O22
HMS2235E10
HMS3369B02
HMS3651I18
HMS3749E07
BCP00087
HY-N0170
Tox21_400055
CCG-38786
HSCI1_000097
NSC525801
s2313
AKOS001075120
AC-7583
CS-7780
DB12881
FI02853
GS-0916
SB14958
SDCCGMLS-0065970.P001
SDCCGMLS-0065970.P002
SMP2_000172
NCGC00090701-01
NCGC00090701-02
NCGC00090701-03
NCGC00090701-04
NCGC00090701-05
NCGC00090701-07
CAS-700-06-1
SY015976
DB-011567
DB-228661
NS00005466
SW219849-1
EN300-18594
A836732
SR-01000838318
Q1770257
SR-01000838318-3
BRD-K01815685-001-02-3
BRD-K01815685-001-07-2
BRD-K01815685-001-15-5
Z85923165
Indole-3-carbinol;Indole-3-methanol;3-Hydroxymethylindole;1H-Indol-3-ylmethanol
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