1H-indol-5-yl 3-(2-aminoethyl)hexanoate

Identification

Molecular formula

C₁₆H₂₂N₂O₂

CAS number

37054-12-3

IUPAC name

1H-indol-5-yl 3-(2-aminoethyl)hexanoate

State

At room temperature, this compound is typically a solid given the relatively high melting point in the range of 88 °C (361 K). The solid form is commonly used in research and industrial contexts.

Melting point (Celsius)

88.50

Melting point (Kelvin)

361.60

Boiling point (Celsius)

372.70

Boiling point (Kelvin)

645.90

General information

Molecular weight

258.35g/mol

Molar mass

258.3530g/mol

Density

1.1660g/cm³

Appearence

This compound generally appears as a white or off-white crystalline solid. The exact appearance can vary based on purity and form, whether it’s powdered or crystalline.

Comment on solubility

Solubility of 1H-indol-5-yl 3-(2-aminoethyl)hexanoate

The solubility of 1H-indol-5-yl 3-(2-aminoethyl)hexanoate is influenced by several factors, including its molecular structure and interactions with solvents. Some key points to consider include:

Polar vs Nonpolar Characteristics: The presence of both an indole and an amino group in the compound may lead to polar interactions with water, promoting some level of solubility.
Hydrophobic Chain: The hexanoate portion of the molecule is hydrophobic, which can reduce overall solubility in aqueous environments but may enhance solubility in organic solvents.
pH Dependency: The solubility can be affected by the pH of the solution due to the ionizable amine group, making it more soluble in basic conditions.

In practical scenarios, 1H-indol-5-yl 3-(2-aminoethyl)hexanoate may exhibit:

Higher solubility in organic solvents such as ethanol or acetone
Limited solubility in pure water, depending on temperature and pH

In summary, the solubility of this compound is a balance of its structural elements and the nature of the solvent used. Therefore, testing in various solvents is recommended to fully understand its solubility profile.

Interesting facts

Interesting Facts about 1H-indol-5-yl 3-(2-aminoethyl)hexanoate

1H-indol-5-yl 3-(2-aminoethyl)hexanoate is a fascinating compound that combines the rich structure of indole with an aminoethyl side chain, making it a molecule of interest in medicinal chemistry and biochemistry. Here are some intriguing aspects:

Indole Backbone: The indole structure is a fused bicyclic compound known for its presence in many biological molecules, including the neurotransmitter serotonin. This makes 1H-indol-5-yl 3-(2-aminoethyl)hexanoate potentially relevant in the field of neurochemistry.
Biological Activity: Compounds like this often exhibit a range of biological activities, including anti-inflammatory, analgesic, and potentially anticancer properties. The presence of the aminoethyl group may play a role in enhancing these effects.
Versatile Synthesis: The synthetic routes to obtain amino acids and their derivatives can offer chemists various pathways to create related compounds, which can help in developing new pharmaceuticals and therapeutic agents.
Potential for Drug Development: Compounds with amino acid-like structures can be utilized in drug design, particularly in creating more effective drug delivery systems or improving the bioavailability of medicinal compounds.
Market Relevance: The pharmaceutical industry shows increasing interest in indole derivatives, paving the way for novel medications that could address a wide range of health issues.

In conclusion, 1H-indol-5-yl 3-(2-aminoethyl)hexanoate represents a promising platform for research and development. Scientist's exploration of such compounds is crucial for discovering new pharmacological agents and understanding their mechanisms of action within biological systems. As the quote goes, "Science knows no country, because knowledge belongs to humanity, and is the torch which illuminates the world." Pursuing the potential of this compound could surely add to that illumination.