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Indole-3-carbohydrazide

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Identification
Molecular formula
C9H9N3O
CAS number
451-54-9
IUPAC name
1H-indole-3-carbohydrazide
State
State

At room temperature, indole-3-carbohydrazide is in a solid state. This property is commonly utilized in its applications in organic synthesis and reactions involving indole derivatives.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.00
Boiling point (Celsius)
371.00
Boiling point (Kelvin)
644.00
General information
Molecular weight
175.19g/mol
Molar mass
175.1920g/mol
Density
1.2800g/cm3
Appearence

Indole-3-carbohydrazide appears as a crystalline solid. The compound is typically off-white in color. Its crystalline nature allows it to be used in various applications in chemical synthesis and research.

Comment on solubility

Solubility of 1H-Indole-3-carbohydrazide

The solubility of 1H-indole-3-carbohydrazide in various solvents can vary significantly, which is an important consideration in its applications. This compound is known for its unique properties; hence understanding its solubility is crucial for practical uses.

Key Points on Solubility:

  • Solvent Dependence: The solubility of 1H-indole-3-carbohydrazide can be influenced by the choice of solvent. It is generally more soluble in polar solvents.
  • Temperature Effect: Like many organic compounds, its solubility tends to increase with temperature. This means higher temperatures can facilitate more effective dissolution.
  • pH Sensitivity: The solubility may also be affected by the pH of the solution, making it essential to do experiments in controlled pH environments.

As a general observation, 1H-indole-3-carbohydrazide exhibits limited solubility in non-polar solvents, which can restrict its applications in various fields, including pharmaceuticals and organic synthesis. Therefore, it is advisable to conduct specific solubility tests in the intended working conditions to ensure optimal results.

Interesting facts

Exploring 1H-Indole-3-Carbohydrazide

1H-Indole-3-carbohydrazide is an intriguing organic compound that has garnered considerable attention in the fields of medicinal chemistry and drug discovery. Here are some fascinating aspects of this compound:

  • Biological Significance: This compound is recognized for its potential biological activities, particularly in cancer research. Studies suggest that it may exhibit anti-cancer properties, making it a target for further investigation in therapeutic applications.
  • Indole Framework: The indole structure is a key feature of many biologically active compounds. Its unique bicyclic arrangement allows for diverse chemical reactivity and interactions within biological systems.
  • Synthetic Versatility: One of the compelling aspects of 1H-indole-3-carbohydrazide is its accessibility through various synthetic routes. Researchers can modify its structure to explore different derivatives, enhancing its potential pharmacological properties.
  • Research Opportunities: As a research chemist, the compound presents a valuable opportunity for exploration. Its functional groups can lead to a wide range of reactions, enabling the synthesis of novel compounds with desired biological activities.
  • Collaborative Research: The interdisciplinary nature of studying compounds like 1H-indole-3-carbohydrazide encourages collaboration among chemists, biologists, and pharmacologists, furthering our understanding of its applications in drug development.

In summary, 1H-indole-3-carbohydrazide is more than just a chemical compound; it represents a crossroads of chemistry, biology, and medicine, holding the potential for impactful discoveries in the pharmaceutical industry and beyond. As we continue to unravel its mysteries, it could pave the way for innovative therapeutic strategies.

Synonyms
1H-indole-3-carbohydrazide
1H-Indole-3-carboxylic acid hydrazide
673-252-8
15317-58-5
MFCD00464063
indole-3-carbohydrazide
INDOLE-3-CARBOXYLIC ACID, HYDRAZIDE
1H-Indole-3-carboxylic acid, hydrazide
BRN 0154574
1H-Indole-3-carboxylicacid, hydrazide
BAS 01060496
Oprea1_426499
Oprea1_440931
5-22-03-00034 (Beilstein Handbook Reference)
SCHEMBL474836
SCHEMBL29135561
DTXSID90165238
QHUYDKZSGDJDSC-UHFFFAOYSA-N
ALBB-002504
BBL015325
SBB009151
STK158150
AKOS000116222
AB06183
SY045452
DB-063973
CS-0074466
ST45138876
EN300-03661
4P-091
Z56955973
F2111-0019