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1H-pyrido[2,3-b][1,4]thiazin-2-one

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Identification
Molecular formula
C8H6N2OS
CAS number
70098-14-5
IUPAC name
1H-pyrido[2,3-b][1,4]thiazin-2-one
State
State

At room temperature, 1H-pyrido[2,3-b][1,4]thiazin-2-one is generally found in the solid state. It is stable under typical atmospheric conditions but should be stored in a cool, dry place to maintain its integrity.

Melting point (Celsius)
109.00
Melting point (Kelvin)
382.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
162.20g/mol
Molar mass
162.2030g/mol
Density
1.3720g/cm3
Appearence

1H-pyrido[2,3-b][1,4]thiazin-2-one typically appears as a crystalline solid. The color can range from white to pale yellow depending on its purity and specific form. The crystalline nature gives it a distinct shape under magnification, with defined edges and a solid structure.

Comment on solubility

Solubility of 1H-pyrido[2,3-b][1,4]thiazin-2-one

The solubility of 1H-pyrido[2,3-b][1,4]thiazin-2-one presents an intriguing case in terms of its behavior in various solvents.

  • Water Solubility: This compound is generally considered to be poorly soluble in water. This limited solubility can be attributed to the hydrophobic nature of the aromatic ring structure, which tends to repulse water molecules.
  • Organic Solvents: Conversely, 1H-pyrido[2,3-b][1,4]thiazin-2-one exhibits much better solubility in organic solvents, especially:
    • Dimethyl sulfoxide (DMSO)
    • Acetone
    • Ethanol
  • pH Dependence: The solubility may also exhibit a pH dependence; adjustments in the pH of the solvent can influence the ionization of the compound, thereby affecting its solubility profile.

In summary, while 1H-pyrido[2,3-b][1,4]thiazin-2-one is poorly soluble in water, it finds better compatibility in organic solvents, presenting unique implications for its use in various chemical applications.

Interesting facts

Interesting Facts about 1H-pyrido[2,3-b][1,4]thiazin-2-one

1H-pyrido[2,3-b][1,4]thiazin-2-one, often seen in the realm of organic chemistry, is a fascinating compound with a variety of applications and intriguing properties. Here are some notable points:

  • Unique Structure: This compound belongs to a class of heterocyclic compounds, which means it contains atoms of at least two different elements in its ring structure. Specifically, it features a pyridine ring fused to a thiazine, showcasing invaluable chemical diversity.
  • Biological Significance: Compounds with similar structures have been investigated for their potential as pharmaceuticals, especially as antimicrobial agents. Their unique fusion of nitrogen and sulfur atoms opens avenues for molecular interactions that can be exploited in drug design.
  • Synthesis Routes: The synthesis of 1H-pyrido[2,3-b][1,4]thiazin-2-one can often involve a series of intricately designed reactions. This makes it an excellent candidate for students learning about synthetic pathways in organic chemistry.
  • Research Interest: Scientists are particularly interested in how the electronic properties of the compound can influence its reaction mechanisms. Investigations into its electronic structure can reveal how it interacts with various biological targets.
  • Applications in Material Science: Beyond pharmaceuticals, derivatives of this compound are increasingly being explored for their potential use in materials science, particularly in developing new organic semiconductors.

"The beauty of chemistry lies in its ability to connect simple elements into complex structures with valuable properties." This saying rings true in the case of 1H-pyrido[2,3-b][1,4]thiazin-2-one, proving that even less commonly discussed compounds can hold secrets of great chemical importance.


In summary, 1H-pyrido[2,3-b][1,4]thiazin-2-one is not just a mere compound; it is a gateway into diverse realms of research and application, making it a captivating topic for both chemists and students alike.

Synonyms
18504-81-9
1H-Pyrido[2,3-b][1,4]thiazin-2(3H)-one
Abbott 29590
Abbott-29590
2PL1478Z1W
1H-Pyrido(2,3-b)(1,4)thiazin-2(3H)-one
DTXSID60171705
DTXCID6094196
242-388-6
1H-pyrido[2,3-b][1,4]thiazin-2-one
1H,2H,3H-pyrido[2,3-b][1,4]thiazin-2-one
2,3-dihydro-1H-pyrido(2,3-b)(1,4)thiazin-2-one
EINECS 242-388-6
BRN 0513741
UNII-2PL1478Z1W
2,3-Dihydro-1-H-pyridino(2,3-b)(1,4)thiazine-2-one
SCHEMBL706780
SCHEMBL6080268
2,3-dihydro-1H-pyridino(2,3-b)(1,4)thiazine-2-one
ALBB-033925
AKOS004911548
NS00026067
H47295
Q27255421
1-H-PYRIDO(2,3-B)(1,4)THIAZINE-2(3H)-ONE
F1907-1469