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Pyrrolo[2,3-c]pyridine

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Identification
Molecular formula
C7H6N2
CAS number
25342-71-6
IUPAC name
1H-pyrrolo[2,3-c]pyridine
State
State

Pyrrolo[2,3-c]pyridine is typically found as a solid at room temperature.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
104.14g/mol
Molar mass
104.1210g/mol
Density
1.1839g/cm3
Appearence

Pyrrolo[2,3-c]pyridine is a pale yellow to light brown solid. It is a heterocyclic aromatic compound featuring a fused pyrrole and pyridine ring system.

Comment on solubility

Solubility of 1H-pyrrolo[2,3-c]pyridine

1H-pyrrolo[2,3-c]pyridine, with its unique heterocyclic structure, exhibits interesting solubility properties that are influenced by several factors. Understanding its solubility is crucial for applications in pharmaceutical and material sciences. Here are some key points regarding the solubility of this compound:

  • Solvent Dependence: The solubility of 1H-pyrrolo[2,3-c]pyridine can vary significantly depending on the solvent used. It is typically more soluble in polar organic solvents such as dimethyl sulfoxide (DMSO) and ethanol.
  • Temperature Effects: Increased temperature generally enhances solubility. As the temperature rises, the kinetic energy of the molecules increases, promoting dissolution.
  • Concentration Limits: While it may be soluble in certain solvents, there are limits to how concentrated a solution can be before precipitation occurs.
  • Hydrogen Bonding: The presence of nitrogen atoms in its structure allows for potential hydrogen bonding, further affecting its interaction with solvents.

As with many organic compounds, the electronic structure and functional groups present in 1H-pyrrolo[2,3-c]pyridine play a pivotal role in defining its solubility characteristics. Understanding these properties is not only essential for lab applications but also for optimizing formulations for various chemical and industrial applications.

Interesting facts

Exploring 1H-pyrrolo[2,3-c]pyridine

1H-pyrrolo[2,3-c]pyridine is a fascinating compound that belongs to a class of heterocyclic aromatic organic compounds. These types of compounds are notable for their roles in various fields, including pharmaceuticals, agrochemicals, and materials science. Here are some interesting aspects of 1H-pyrrolo[2,3-c]pyridine:

  • Structural Significance: It features a unique bicyclic structure that consists of both pyrrole and pyridine rings, offering a rich framework for further chemical modifications.
  • Biological Activity: Compounds in this class have been investigated for their potential pharmacological properties, including anti-cancer and anti-inflammatory activities. It's a compelling area of research for medicinal chemists.
  • Versatile Functions: The availability of reactive positions in its structure allows 1H-pyrrolo[2,3-c]pyridine derivatives to serve as intermediates in synthesizing more complex molecules.
  • Applications in Material Science: This compound and its derivatives can be utilized in the development of new materials, including dyes and polymers, due to their electronic properties.
  • Research Potential: Ongoing studies are revealing new synthetic routes and applications, showcasing the compound's importance in the evolution of material and pharmaceutical sciences.

As we continue to explore the potential of 1H-pyrrolo[2,3-c]pyridine, its unique structure and versatile applications remind us of the excitement and complexity inherent in the world of organic chemistry. Each new discovery opens doors to developments that can significantly impact various scientific domains.

Synonyms
6-AZAINDOLE
271-29-4
1H-pyrrolo[2,3-c]pyridine
1,6-Diazaindene
Harmyrine
6H-PYRROLO[2,3-C]PYRIDINE
1H-Pyrrolo(2,3-c)pyridine
271-28-3
MFCD01686899
BRN 0109685
DTXSID20181562
5-23-06-00305 (Beilstein Handbook Reference)
pyrrolo[2,3-c]pyridine
SCHEMBL12470
CHEMBL5208607
SCHEMBL22959960
DTXCID60104053
ALBB-037866
BCP26482
BBL103029
STL556838
AKOS000782863
AKOS006240281
AC-1651
CS-W002819
FA05653
PB21773
PS-4926
1H-Pyrrolo[2,3-c]pyridine, AldrichCPR
BP-20630
SY005848
DB-007119
P2530
EN300-56937
Z871773918
InChI=1/C7H6N2/c1-3-8-5-7-6(1)2-4-9-7/h1-5,9
664-233-5