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1H-Quinolin-7-one

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Identification
Molecular formula
C9H7NO
CAS number
766-18-3
IUPAC name
1H-quinolin-7-one
State
State

1H-Quinolin-7-one is typically in a solid state at room temperature. It exists as a crystalline powder and is stable under normal conditions of storage and handling.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.15
Boiling point (Celsius)
309.00
Boiling point (Kelvin)
582.15
General information
Molecular weight
145.16g/mol
Molar mass
145.1580g/mol
Density
1.3183g/cm3
Appearence

1H-Quinolin-7-one appears as a yellow solid crystalline powder. Its appearance can sometimes vary slightly depending on the level of purity and specific preparation methods, but the yellow color tends to be a consistent characteristic.

Comment on solubility

Solubility of 1H-quinolin-7-one

1H-quinolin-7-one, characterized by its unique heterocyclic structure, exhibits interesting solubility properties. This compound is primarily known for its role in various chemical reactions and as a precursor in synthesizing more complex molecules.

Solubility Characteristics

Here are some key points regarding the solubility of 1H-quinolin-7-one:

  • Solvent Compatibility: 1H-quinolin-7-one is generally soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO).
  • Water Solubility: It exhibits limited solubility in water which is a common characteristic of many heterocyclic aromatic compounds.
  • Temperature Effects: The solubility of 1H-quinolin-7-one may increase with temperature, making it essential to consider thermal effects in applications.

Overall, while the solubility of 1H-quinolin-7-one in polar solvents like water is low, its solubility in organic solvents provides flexibility for various chemical applications. As one researcher noted, “the solubility profile of compounds like 1H-quinolin-7-one can significantly influence their reactivity and utility in synthetic chemistry.”

In summary, understanding the solubility of 1H-quinolin-7-one aids in its practical applications and can influence the design of experiments involving this intriguing compound.

Interesting facts

Interesting Facts about 1H-quinolin-7-one

1H-quinolin-7-one, also known as 7-quinolone, is a fascinating compound that holds significant interest in various fields of study, particularly medicinal chemistry. Here are some compelling facts about this intriguing chemical:

  • Bioactivity: 1H-quinolin-7-one has been noted for its potential biological activities, including antimicrobial, anti-inflammatory, and anticancer properties. This makes it a subject of investigation for developing new pharmaceuticals.
  • Structural Insights: The compound features a unique bicyclic structure, which includes a quinoline ring system. This structure is crucial as it influences the compound's reactivity and biological interactions.
  • Synthesis Techniques: Researchers have developed various synthetic methods to produce 1H-quinolin-7-one, including Pyridine-based reactions and Cyclization reactions, making it an appealing compound for organic synthesis.
  • Applications: Beyond medicinal uses, 1H-quinolin-7-one is explored in fields such as material science and photochemistry, demonstrating its versatility in different domains.
  • Role in Research: The compound serves as a versatile scaffold for the development of other chemical entities, often leading to compounds with enhanced bioactivity and lower toxicity profiles.

As the field of chemistry evolves, compounds like 1H-quinolin-7-one continue to capture the attention of scientists and researchers. Its unique properties and potential applications herald exciting possibilities for future discoveries!