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Tramadol

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Identification
Molecular formula
C16H25NO2
CAS number
27203-92-5
IUPAC name
(1R,11R,14R)-14-ethynyl-5-methoxy-15-methyl-10-azatetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-trien-14-ol
State
State

Tramadol is a solid at room temperature.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
263.38g/mol
Molar mass
263.3840g/mol
Density
1.2083g/cm3
Appearence

Tramadol appears as a white crystalline powder. It is typically odorless or has a faint odor and is sparingly soluble in water.

Comment on solubility

Solubility of (1R,11R,14R)-14-ethynyl-5-methoxy-15-methyl-10-azatetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-trien-14-ol

The solubility of this complex molecule is influenced by its unique structural characteristics and functional groups. Understanding its solubility properties is crucial for potential applications and biological interactions. Here are some important points to consider:

  • Polarity: The presence of the methoxy group increases polarity, which can enhance solubility in polar solvents like water.
  • Hydrophobic regions: The cyclic structure introduces hydrophobic regions that may hinder solubility in some aqueous environments.
  • Solvent compatibility: This compound may demonstrate better solubility in organic solvents such as ethanol or DMSO due to its overall structure.
  • Temperature dependency: Solubility may vary significantly with temperature, often increasing at elevated temperatures.
  • pH Influence: The ionization of functional groups under varying pH levels can also affect solubility, necessitating evaluation at different conditions.

In conclusion, while the solubility of (1R,11R,14R)-14-ethynyl-5-methoxy-15-methyl-10-azatetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-trien-14-ol may be favorable in certain solvents, its intricate structure requires careful consideration of various factors to determine its behavior in solution.

Interesting facts

Interesting Facts about (1R,11R,14R)-14-ethynyl-5-methoxy-15-methyl-10-azatetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-trien-14-ol

This fascinating compound, often referred to by its systematic nomenclature, belongs to a group of molecules known for their complex structures and significant biological activity. Here are some intriguing insights:

  • Structural Complexity: The compound showcases a distinctive tetracyclic framework, which is characteristic of many natural products. This complexity often leads to unique chemical properties and behaviors in biological systems.
  • Biological Relevance: Compounds with similar structures are known to exhibit noteworthy pharmacological activities. They often play roles in medicinal chemistry, potentially serving as leads for drug development.
  • Synthetic Challenges: The synthesis of such complex molecules can involve intricate multi-step processes. This makes their synthesis a subject of interest in the field of organic chemistry, where chemists strive to develop efficient and sustainable methods for their production.
  • Applications in Science: Research has shown that the modifications present in this compound can provide insights into synthesis strategies. Understanding such compounds can lead to advances in areas like biochemistry, pharmacology, and natural product synthesis.
  • Potential Uses: This compound could have implications in the development of new therapies, particularly if related compounds are confirmed to possess activities against diseases.

In conclusion, the study of (1R,11R,14R)-14-ethynyl-5-methoxy-15-methyl-10-azatetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-trien-14-ol not only showcases the beauty of chemical diversity but also opens doors to new research avenues. As we continue to unlock the potential of such complex molecules, we embrace the exciting challenges and breakthroughs they bring to science.