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(1R,2R)-2-cyanocyclobutanecarboxamide

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Identification
Molecular formula
C6H8N2O
CAS number
939758-63-9
IUPAC name
(1R,2R)-2-cyanocyclobutanecarboxamide
State
State

At room temperature, (1R,2R)-2-cyanocyclobutanecarboxamide exists in a solid state, typically as a crystalline powder.

Melting point (Celsius)
72.00
Melting point (Kelvin)
345.15
Boiling point (Celsius)
305.20
Boiling point (Kelvin)
578.35
General information
Molecular weight
124.14g/mol
Molar mass
124.1440g/mol
Density
1.1800g/cm3
Appearence

(1R,2R)-2-cyanocyclobutanecarboxamide is a colorless crystalline solid that is often available in a powder form. It typically has a white or off-white coloration.

Comment on solubility

Solubility of (1R,2R)-2-cyanocyclobutanecarboxamide

(1R,2R)-2-cyanocyclobutanecarboxamide is a fascinating organic compound characterized by its unique structural features. Understanding its solubility is crucial for applications in various fields, from pharmaceuticals to materials science.

The solubility of this compound can be influenced by several key factors:

  • Polarity: The presence of a cyano group (-CN) and a carboxamide group (-CONH2) suggests that the compound has polar characteristics, which may enhance its solubility in polar solvents.
  • Hydrogen Bonding: The ability of the -CONH2 group to participate in hydrogen bonding can lead to increased solubility in water and other hydrogen-bonding solvents.
  • Chain Length: The cyclobutane ring adds a certain degree of rigidity and steric hindrance, which can impact interactions with solvent molecules.

Typically, compounds that are polar or capable of hydrogen bonding tend to be more soluble in polar solvents such as water and alcohols. However, the overall solubility parameters should be experimentally determined, as they can vary based on concentration and temperature conditions.

In conclusion, while preliminary predictions can be made based on the functional groups present, the full solubility profile of (1R,2R)-2-cyanocyclobutanecarboxamide necessitates empirical analysis to comprehend its behavior in different solvents.

Interesting facts

Interesting Facts About (1R,2R)-2-cyanocyclobutanecarboxamide

(1R,2R)-2-cyanocyclobutanecarboxamide is a fascinating chemical compound that has garnered interest due to its unique structure and potential applications. Here are some intriguing points about this compound:

  • Chirality: The notation (1R,2R) indicates that this compound has a chiral center, which gives rise to different enantiomers. Chirality plays a crucial role in pharmacology, as different enantiomers can exhibit vastly different biological activities.
  • Structural Attributes: The cyclobutane ring structure imparts distinctive strain and reactivity characteristics not found in larger cyclic compounds. This can lead to interesting synthetic pathways and reactivity that chemists often explore in organic synthesis.
  • Biological Relevance: Compounds with amide functional groups are often of great interest in medicinal chemistry due to their ability to form hydrogen bonds. This can enhance the bioavailability and efficacy of drug candidates.
  • Synthetic Applications: The building block nature of (1R,2R)-2-cyanocyclobutanecarboxamide makes it a versatile intermediate, potentially useful in the synthesis of more complex organic molecules, including pharmaceuticals and agrochemicals.
  • Research Potential: The unique properties of this compound suggest it could be a subject of study for new materials or catalytic processes, furthering our understanding of synthetic methods and material science.

As a prominent example of how structural nuances can lead to diverse applications, (1R,2R)-2-cyanocyclobutanecarboxamide invites researchers to unlock its secrets and explore its potential in various fields of chemistry and material science.

Synonyms
NSC 527263
CYCLOBUTANECARBOXAMIDE, 2-CYANO-, trans-
trans-2-Cyanocyclobutanecarboxamide
16200-68-3
USAF ST-16
AKOS006362067