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(1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine

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Identification
Molecular formula
C9H9Cl2NO
CAS number
98240-94-5
IUPAC name
(1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine
State
State

At room temperature, (1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine is in a solid state.

Melting point (Celsius)
64.00
Melting point (Kelvin)
337.20
Boiling point (Celsius)
278.50
Boiling point (Kelvin)
551.60
General information
Molecular weight
217.07g/mol
Molar mass
217.0700g/mol
Density
1.3900g/cm3
Appearence

The compound is typically a colorless to light yellow crystalline solid. It may appear in powder form and is not highly soluble in water, increasing its stability under standard conditions.

Comment on solubility

Solubility of (1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine

The solubility of (1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine in various solvents is influenced by its unique structure and the presence of functional groups. Here are some insights regarding its solubility:

  • Polar Solvents: Compounds with polar functional groups often exhibit greater solubility in polar solvents like water. However, the solubility of this compound in water can be limited due to steric hindrance and hydrophobic character introduced by the chlorophenyl group.
  • Non-Polar Solvents: It is likely to show better solubility in non-polar solvents, including hydrocarbons and certain organic solvents like dichloromethane and ethyl acetate, where the non-polar cyclopropane structure may be more compatible.
  • Temperature Effects: Solubility generally increases with temperature. Therefore, solubilizing (1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine at elevated temperatures may enhance its dissolution in chasing solvents.
  • pH Impact: The pH level of the solvent can also affect solubility, especially if the compound can undergo protonation or deprotonation, altering its ionic form and solubility profile.

In summary, while the structural features and solvent characteristics play significant roles in determining the solubility of (1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine, practical experimentation remains essential to establish precise solubility parameters.

Interesting facts

Interesting Facts about (1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine

(1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine is a compound that has captured the interest of scientists for its unique structural and functional properties. This compound belongs to a class of molecules known for their role in various biological activities, which makes it a valuable subject of study.

Notable Characteristics

  • Stereochemistry: The designation of (1R,2S) indicates the specific 3D arrangement of atoms, which is crucial in determining how the molecule interacts with biological systems. Stereochemistry can profoundly influence the compound's biological activity.
  • Functional Groups: The inclusion of a dichlorophenyl group enhances the compound’s lipophilicity, potentially increasing its ability to penetrate biological membranes. This characteristic can influence the compound's pharmacokinetics and pharmacodynamics.
  • Cyclopropane Ring: The cyclopropane portion of the molecule is noteworthy due to its strain and reactivity. Cyclopropanes often serve as building blocks in organic synthesis, leading to innovative pharmaceutical compounds.

Applications and Research

This compound has garnered interest in several fields, particularly in medicinal chemistry and pharmacology. Research suggests that derivatives of compounds containing such structures may exhibit:

  • Antidepressant properties
  • Neuroprotective effects
  • A potential role in treating various neurological disorders

As noted in recent studies, “The ability of such compounds to interact with specific neurotransmitter systems makes them promising candidates for further therapeutic exploration.” This statement underscores the ongoing investigations into the pharmacological potential of (1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine.

Conclusion

In summary, (1R,2S)-2-(2,6-dichlorophenoxy)cyclopropanamine represents an intriguing blend of structural complexity and potential biological significance. With continued research, it may contribute to the development of new therapeutic agents, showcasing the ever-evolving relationship between chemical compounds and their applications in medicine.