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(1R,3S)-3-methylcyclohexanol

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Identification
Molecular formula
C7H14O
CAS number
77463-58-8
IUPAC name
(1R,3S)-3-methylcyclohexanol
State
State

At room temperature, (1R,3S)-3-methylcyclohexanol is typically in a liquid state. This is common for many cyclohexanol derivatives, indicating their relative volatility and stability in liquid form at ambient conditions.

Melting point (Celsius)
-8.00
Melting point (Kelvin)
265.15
Boiling point (Celsius)
189.50
Boiling point (Kelvin)
462.65
General information
Molecular weight
114.19g/mol
Molar mass
114.1860g/mol
Density
0.9435g/cm3
Appearence

(1R,3S)-3-methylcyclohexanol is a colorless liquid at room temperature. Its appearance can be characterized by its clear and transparent look, similar to other cyclohexanols.

Comment on solubility

Solubility of (1R,3S)-3-methylcyclohexanol

(1R,3S)-3-methylcyclohexanol is a chiral alcohol with interesting solubility characteristics. Its solubility can be influenced by a variety of factors, including temperature, polarity, and the presence of other solutes. Here are some key points regarding its solubility:

  • Polarity: As a secondary alcohol, (1R,3S)-3-methylcyclohexanol exhibits moderate polarity due to the hydroxyl (-OH) group, making it more soluble in polar solvents.
  • Solvent Compatibility: It is expected to show good solubility in polar organic solvents like ethanol and dimethyl sulfoxide (DMSO), while exhibiting limited solubility in non-polar solvents such as hexane.
  • Temperature Effect: Increasing the temperature generally enhances the solubility of organic compounds, including this alcohol, allowing for better interactions with solvent molecules.

In summary, one can expect (1R,3S)-3-methylcyclohexanol to be soluble in polar solvents but less so in non-polar environments, highlighting the importance of solvent choice in practical applications. As always, the specific solubility can vary based on conditions, so conducting solubility tests is advisable for precise use.

Interesting facts

Interesting Facts about (1R,3S)-3-methylcyclohexanol

(1R,3S)-3-methylcyclohexanol is a fascinating compound with significant importance in organic chemistry and various applications.

Structural Characteristics

This compound features a cyclohexane ring that plays a vital role in its chemical properties. Its chiral centers at positions 1 and 3 lend it particular stereochemistry, making it an interesting subject of study in stereochemistry. Here are a few unique aspects:

  • Stereochemistry: The specific configuration of (1R,3S) leads to distinct optical activity, making it valuable in asymmetric synthesis.
  • Isomerism: It exists in multiple isomeric forms, which can exhibit different physical and chemical properties, further enhancing its studious appeal.

Applications

The applications of (1R,3S)-3-methylcyclohexanol span various fields:

  • Flavor and Fragrance: This compound is utilized in the fragrance industry due to its pleasant odor profile, often being used as a flavoring agent in food products.
  • Solvent: It can serve as an excellent solvent for organic reactions and various formulations in industrial settings.

Research and Development

In the domain of chemical research, the study of (1R,3S)-3-methylcyclohexanol has contributed to innovations in:

  • Chiral Catalysis: The compound has been explored as a potential chiral catalyst in organic synthesis, showcasing its versatility.
  • Pharmaceutical Chemistry: Its unique structural features can influence the pharmacological activity of drug candidates, which is a focal point in medicinal chemistry.

Overall, (1R,3S)-3-methylcyclohexanol exemplifies the beauty of organic compounds, showcasing how structural nuances can lead to a plethora of applications and research opportunities. Its combination of practical applications and intriguing chemical properties makes it a worthy subject for chemistry enthusiasts and professionals alike.

Synonyms
cis-3-Methylcyclohexanol
Cyclohexanol, 3-methyl-, cis-
5454-79-5
NSC 23234
3-Methyl cyclohexanol, cis
3-Methylcyclohexanol, (Z)-
Cyclohexanol, 3-methyl-, cis-(8CI)
Cyclohexanol, 3-methyl-, cis-(8CI)(9CI)
htsabyawkqahbt-nkwvepmbsa-n
htsabyawkqahbt-rqjhmyqmsa-n
(1R,3S)-3-methylcyclohexan-1-ol
24965-91-1
CYCLOHEXANOL, 3-METHYL-, (1R,3S)-
cis-3-Methylcyclohexan-1-ol
24965-90-0
SCHEMBL440953
DTXSID001031658