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Hypocrellin A

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Identification
Molecular formula
C22H20O6
CAS number
79453-53-7
IUPAC name
(1R,3S)-9-methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione
State
State

At room temperature, Hypocrellin A is usually encountered as a solid. This state makes it suitable for various applications, especially in solid forms such as powders and tablets used in research and medicinal applications.

Melting point (Celsius)
242.00
Melting point (Kelvin)
515.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
372.40g/mol
Molar mass
372.3700g/mol
Density
1.4600g/cm3
Appearence

Hypocrellin A is a red-orange crystalline powder. It is known for its vibrant color, which is typical for a compound containing conjugated aromatic systems. This appearance is significant for its applications, particularly in dye-sensitized therapies and as a pigment.

Comment on solubility

Solubility of (1R,3S)-9-methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione

The solubility of (1R,3S)-9-methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione can be quite intriguing due to its complex structure. Understanding its solubility is crucial for applications in various fields such as pharmaceuticals and chemical synthesis. Here are some important considerations:

  • Solvent Polarity: This compound's solubility is likely influenced by the polarity of the solvent. Nonpolar solvents often favor the dissolution of organic compounds, while polar solvents may not.
  • Temperature Influence: Elevated temperatures can enhance solubility for many organic compounds, so testing at various temperatures can provide valuable insights.
  • Functional Groups Interaction: The presence of methoxy groups (–OCH3) can enhance solubility in polar organic solvents, while the overall hydrophobic nature may limit solubility in water.
  • pH Sensitivity: The solubility may vary with pH, particularly if ionizable groups are present, affecting the compound's overall charge and solvation behavior.

In conclusion, the solubility of this compound is a multifaceted aspect that warrants careful investigation and could be tailored by varying the solvent environment. As stated, "Solubility is the key to understanding reactivity and incorporation in various matrices," making it essential to explore how it interacts in different conditions.

Interesting facts

Interesting Facts about (1R,3S)-9-methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione

This intriguing compound belongs to a unique class of chemical compounds that exhibit fascinating structural characteristics and potential biological activities. Here are some noteworthy aspects:

  • Stereochemistry: The notation (1R,3S) indicates the specific 3D arrangement of atoms in this molecule, which plays a critical role in its chemical behavior and interactions with biological systems.
  • Functional Groups: The compound features both a methoxy group and a diketone structure, which are significant for its reactivity and solubility properties in various solvents.
  • Isochromene Framework: It contains an isochromene core—a structure that is interesting in medicinal chemistry due to its many derivatives that exhibit pharmacological effects.

The structure of this compound allows it to potentially engage in various biological interactions, making it a subject of interest for researchers in pharmacology. Compounds like this one can serve as a template for the design of new therapeutic agents, especially in the field of cancer research and neurochemistry.

As noted by chemists, "The beauty of organic chemistry lies not only in the compounds we study but in the stories they tell and the futures they promise." This particular compound exemplifies such potential, inspiring future studies that may unlock its capabilities.

In summary, (1R,3S)-9-methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione captures the attention of scientists due to its complex structure and possible applications in therapeutic contexts, making it an exciting candidate for ongoing research.

Synonyms
Eleutherin
478-36-4
(+)-Eleutherin
BRN 0087122
(+/-)-Eleutherin
1H-Naphtho[2,3-c]pyran-5,10-dione, 3,4-dihydro-9-methoxy-1,3-dimethyl-, (1R,3S)-
Eleutherin, (+/-)-
9J86WO1VYK
(1R,3S)-9-methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione
7FTP57M80A
CHEBI:4774
1H-Naphtho(2,3-c)pyran-5,10-dione, 3,4-dihydro-9-methoxy-1,3-dimethyl-, (1R-cis)-
64869-73-4
(1R,3S)-9-Methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo(g)isochromene-5,10-dione
1H-Naphtho(2,3-C)pyran-5,10-dione, 3,4-dihydro-9-methoxy-1,3-dimethyl-, (1R,3S)-rel-
1H-Naphtho(2,3-C)pyran-5,10-dione, 3,4-dihydro-9-methoxy-1,3-dimethyl-, cis-
1H-Naphtho(2,3-C)pyran-5,10-dione, 3,4-dihydro-9-methoxy-1,3-dimethyl-, cis-(+/-)-
1H-NAPHTHO(2,3-C)PYRAN-5,10-DIONE, 3,4-DIHYDRO-9-METHOXY-1,3-DIMETHYL-, (1R,3S)-
UNII-9J86WO1VYK
3,4-Dihydro-1-beta,3-beta-dimethyl-9-methoxy-1H-naphtho(2,3-c)pyran-5,10-dione
UNII-7FTP57M80A
ELEUTHERIN, (+)-
5-18-03-00554 (Beilstein Handbook Reference)
CHEMBL594153
DTXSID40197281
HY-N8248
AKOS040760849
1H-NAPHTHO(2,3-c)PYRAN-5,10-DIONE, 3,4-DIHYDRO-1-beta,3-beta-DIMETHYL-9-METHOXY-
AC-34300
CS-0141601
H37907
Q27106475
(1R,3S)-3,4-DIHYDRO-9-METHOXY-1,3-DIMETHYL-1H-NAPHTHO(2,3-C)PYRAN-5,10-DIONE
(1R,3S)-9-METHOXY-1,3-DIMETHYL-1H,3H,4H,5H,10H-NAPHTHO[2,3-C]PYRAN-5,10-DIONE
1H-NAPHTHO(2,3-C)PYRAN-5,10-DIONE, 3,4-DIHYDRO-9-METHOXY-1.BETA.,3.BETA.-DIMETHYL-