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Ginsenoside Rg3

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Identification
Molecular formula
C42H72O13
CAS number
14197-60-5
IUPAC name
(1R,4R,5R,7R,9R,13S,15S)-15-hydroxy-7-[(2S,3R,4R,5R,6R)-6-(hydroxymethyl)-3-(3-methylbutanoyloxy)-4,5-disulfooxy-tetrahydropyran-2-yl]oxy-9-methyl-14-methylene-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid
State
State

At room temperature, Ginsenoside Rg3 is a solid. In most cases, it exists as a crystalline powder which is stable under normal conditions and is often utilized in pharmaceutical formulations.

Melting point (Celsius)
270.00
Melting point (Kelvin)
543.00
Boiling point (Celsius)
700.00
Boiling point (Kelvin)
973.00
General information
Molecular weight
785.03g/mol
Molar mass
785.0310g/mol
Density
1.4500g/cm3
Appearence

Ginsenoside Rg3 typically appears as an off-white to pale yellow crystalline powder. It is often used in its powdered form in various pharmaceutical preparations.

Comment on solubility

Solubility of (1R,4R,5R,7R,9R,13S,15S)-15-hydroxy-7-[(2S,3R,4R,5R,6R)-6-(hydroxymethyl)-3-(3-methylbutanoyloxy)-4,5-disulfooxy-tetrahydropyran-2-yl]oxy-9-methyl-14-methylene-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid

The solubility of this intricate compound is quite complex due to its multifaceted structure and functional groups. Understanding its solubility can be critical for various chemical applications. Here are a few points to consider:

  • Polarity: The presence of hydroxyl (-OH) groups typically enhances solubility in polar solvents like water. However, the overall structural complexity could reduce this effect.
  • Sulfonate Groups: The presence of disulfooxy groups may contribute significantly to the compound’s hydrophilicity, thereby promoting solubility in aqueous environments.
  • Hydrophobic Regions: Despite polar functional groups, certain hydrophobic parts of the molecule may lead to reduced solubility in water compared to fully polar compounds.
  • pH Dependence: The solubility might vary with pH, especially for carboxylic acids which can ionize in alkaline conditions, potentially increasing solubility.

In conclusion, while the compound is expected to have some solubility in water due to its polar characteristics, the overall solubility could be moderately affected by its amphiphilic nature and structural intricacies. Testing under various conditions will provide more definitive insights into its solubility behavior.

Interesting facts

Interesting Facts about (1R,4R,5R,7R,9R,13S,15S)-15-hydroxy-7-[(2S,3R,4R,5R,6R)-6-(hydroxymethyl)-3-(3-methylbutanoyloxy)-4,5-disulfooxy-tetrahydropyran-2-yl]oxy-9-methyl-14-methylene-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid

This complex chemical compound is a fascinating example of a natural product with intricate stereochemistry, showcasing the richness of organic molecules found in nature. Here are some intriguing points about this compound:

  • Stereochemistry: The compound features multiple stereocenters, indicated by the (1R,4R,5R,7R,9R,13S,15S) and (2S,3R,4R,5R,6R) designations. Understanding the 3D arrangement of its atoms is crucial for explaining its biological activity.
  • Biological Significance: This molecule could potentially play roles in biochemical pathways, possibly being involved in signaling mechanisms or interactions with biological receptors due to its unique functional groups.
  • Natural Source: Compounds of this type are often derived from natural sources such as plants or microorganisms, suggesting ecological significance and usage in traditional remedies.
  • Research and Applications: The intricate structure provides ample opportunities for medicinal chemistry research. It may inspire the synthesis of new pharmaceuticals, especially in the realm of anti-inflammatory or antimicrobial agents.
  • Complex Synthesis: The synthesis of such compounds is typically a challenge for chemists, involving multiple steps, protective groups, and sometimes the use of advanced techniques in stereoselective synthesis.

In conclusion, the exploration of this compound not only enhances our understanding of chemical functionality but also bolsters the potential in various fields such as pharmacology and environmental chemistry. One might say, "The complexities of natural compounds reflect the complexities of life itself."