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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
(1R,6R,7R,17R)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
State
State

At room temperature, Erythromycin is in a solid state. It is generally stable under normal temperatures and pressures, but care should be taken to protect it from moisture and excessive heat.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9380g/mol
Density
1.2400g/cm3
Appearence

Erythromycin is a white or slightly yellow crystalline powder. It is often supplied in a purified form and may appear as small, white, needle-like crystals. The compound's appearance may vary depending on the specific preparation or formulation, but it is generally odorless.

Comment on solubility

Solubility of (1R,6R,7R,17R)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione

The solubility of the compound (1R,6R,7R,17R)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione can be influenced by various factors including its molecular structure, polarity, and the presence of functional groups. Understanding its solubility features is essential for predicting behavior in various environments.

Key Considerations for Solubility:

  • Polarity: The presence of hydroxyl groups (–OH) typically enhances solubility in polar solvents such as water.
  • Functional Groups: The combination of ether and ketone functionalities may lead to different solubility profiles depending on the solvent.
  • Molecular Weight: Higher molecular weight can reduce solubility in certain solvents due to bulkiness.

While specific solubility data for this compound may not be readily available, it is crucial to conduct experiments to determine solubility accurately. As a rule of thumb, compounds with multiple polar groups tend to be more soluble in polar solvents, whereas non-polar regions suggest solubility in organic solvents.

As famed chemist Joseph Louis Gay-Lussac once said, "All substances that dissolve in water, dissolve in water in a wet way." Therefore, comprehensive solubility studies are necessary to fully understand the behavior of this fascinating compound in different environments.

Interesting facts

Interesting Facts about (1R,6R,7R,17R)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione

This compound is a fascinating example of complex organic chemistry with its intricate structure and unique properties. Here are some key insights:

  • Structural Complexity: The compound features a tricyclic framework, which presents a unique set of challenges for synthesis and analysis. Its specific stereochemistry and functional groups play a crucial role in determining its behavior in chemical reactions.
  • Biological Relevance: Many compounds with similar frameworks have been studied for their potential biological activities, including antimicrobial and anti-inflammatory properties. While specific studies for this compound may be limited, its structural relatives offer promising avenues for pharmaceutical research.
  • Chirality: The presence of multiple stereocenters indicates that this molecule can exist in different enantiomeric forms. Chirality is a significant consideration in the design of drugs, as different enantiomers can exhibit vastly different biological effects.
  • Polyfunctional Nature: This compound contains hydroxy, dioxo, and ethylidene groups, which can participate in a variety of reactions, including hydrogen bonding and coordination with metal ions, expanding its potential for applications in materials science and catalysis.

The study of such compounds not only enhances our understanding of organic synthesis and reactivity but also opens new doors in medicinal chemistry and material development. As noted by a leading researcher, "The complexity of organic molecules often dictates their utility in nature and technology."
This compound exemplifies the beauty and intricacy of chemical compounds, promising exciting opportunities for future research and application.

Synonyms
C18H25NO5
AKOS030254870