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Erythromycin A

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
(1R,6R,7S)-4-ethylidene-7-hydroxy-7-(hydroxymethyl)-6-methyl-14-oxido-2,9-dioxa-14-azoniatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
State
State
At room temperature, erythromycin A is typically a solid.
Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.2400g/cm3
Appearence
Erythromycin A is a white to off-white crystalline powder. It is odorless or nearly odorless, and its crystals or powder form can appear slightly yellow-ish upon exposure to light.
Comment on solubility

Solubility of (1R,6R,7S)-4-ethylidene-7-hydroxy-7-(hydroxymethyl)-6-methyl-14-oxido-2,9-dioxa-14-azoniatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione

The solubility of this complex compound can be influenced by several factors. Its intricate structure, characterized by multiple functional groups, suggests that solubility can vary significantly in different solvents. Here are key considerations:

  • Polarity: The presence of hydroxyl (-OH) groups typically enhances solubility in polar solvents such as water. Therefore, it is expected that this compound may demonstrate better solubility in polar environments.
  • Steric Hindrance: The bulky ethylidene and methyl groups may create steric hindrance, which could impact the ability of solvent molecules to interact with the compound.
  • pH Sensitivity: As a zwitterionic species (due to its azonia group), its solubility may also be affected by the pH of the solution, potentially leading to increased solubility in acidic or basic conditions.
  • Solvent Choice: While polar protic solvents such as water or alcohols might dissolve the compound better, nonpolar solvents may result in poor solubility.

In conclusion, the solubility of (1R,6R,7S)-4-ethylidene-7-hydroxy-7-(hydroxymethyl)-6-methyl-14-oxido-2,9-dioxa-14-azoniatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione is likely to be quite variable. As with many complex organic compounds, experimental assessment is essential to accurately determine its solubility profile across different solvents and conditions.

Interesting facts

Interesting Facts about (1R,6R,7S)-4-ethylidene-7-hydroxy-7-(hydroxymethyl)-6-methyl-14-oxido-2,9-dioxa-14-azoniatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione

This compound, known for its complex structure and noteworthy functionalities, has several fascinating aspects worth discussing:

  • Stereochemistry: The compound features a specific stereochemistry, designated by (1R,6R,7S). This indicates the presence of chiral centers, which can impart unique properties including enantioselectivity in reactions.
  • Oxidative Properties: With its characteristic *oxido* group, the compound may exhibit oxidative capabilities, which could be useful in synthetic organic chemistry or biological applications.
  • Multifunctionality: The existence of multiple functional groups, such as hydroxymethyl and dione, suggests this compound could potentially be a versatile precursor in pharmaceutical design or material science.
  • Biological Relevance: Compounds of this structural type are often studied for their potential biological activity, as many complex natural products exhibit intriguing effects on human health. Research on such compounds may lead to new drug discoveries.
  • Tricyclic Framework: The presence of a tricyclic structure in this compound invites an exploration of its type in the domain of chemistry, as such frameworks can offer unique stability and reactivity patterns.

The study of this compound serves not only to deepen our understanding of complex molecules but also to encourage innovative pathways in research where functionality meets structural intricacies. As noted by chemists, "The essence of chemistry lies in understanding the delicate dance of atoms and their arrangement." Each discovery, including this one, contributes to the grand narrative of molecular exploration.