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Taxol

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Identification
Molecular formula
C47H51NO14
CAS number
33069-62-4
IUPAC name
(1R,6S,9S,10R,11S,14R,19S,23S,25R)-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosane-1,10,11,12,14,22,23-heptol
State
State

At room temperature, Taxol is in a solid state. It is generally stored in a dry place.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
808.15
Boiling point (Kelvin)
1 081.30
General information
Molecular weight
853.91g/mol
Molar mass
853.9060g/mol
Density
1.6300g/cm3
Appearence

Taxol is a white to off-white crystalline powder. It is relatively light and fibrous in appearance.

Comment on solubility

Solubility of (1R,6S,9S,10R,11S,14R,19S,23S,25R)-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosane-1,10,11,12,14,22,23-heptol

The solubility of this complex compound can be quite intriguing due to its extensive structural framework and multiple functional groups. Here are some key points to consider:

  • Solvent Interaction: The presence of hydroxyl groups (–OH) typically enhances solubility in polar solvents, suggesting possible solubility in water and alcohols.
  • Hydrophobic Regions: Conversely, the hydrophobic portions of the molecular structure may hinder solubility in non-polar solvents, limiting interactions.
  • Structural Complexity: The intricate arrangement of the cyclic components may lead to unique aggregation behaviors in various solvent systems.
  • pH Dependence: Changes in pH can alter the ionization of functional groups, potentially impacting solubility and stability.

In summary, the solubility of this compound is likely influenced by a combination of its: polar and non-polar characteristics, functional groups, and environmental factors such as temperature and pH. Further empirical studies would be beneficial to quantify solubility in specific solvents and conditions.

Interesting facts

Interesting Facts about (1R,6S,9S,10R,11S,14R,19S,23S,25R)-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosane-1,10,11,12,14,22,23-heptol

This macrocyclic compound is an intriguing example of complex organic chemistry, showcasing the beauty and intricacy of molecular construction. Here are some fascinating points to ponder:

  • Structural Complexity: The compound features a heptacyclic structure, which means it consists of seven interconnected rings. Such complexity can lead to unique biological activities and properties.
  • Substituents Matter: The presence of multiple methyl groups greatly influences the compound's reactivity and solubility, potentially allowing for varied interactions in biological systems.
  • Oxygen and Nitrogen Integration: The incorporation of oxygen and nitrogen in the structure enhances its potential for forming hydrogen bonds, which might contribute to its biological function and stability.
  • Tuning Properties: The specific stereochemistry, as indicated by the stereocenters in the name, suggests tailored interactions with enzymes or receptors, making the compound a possible candidate for drug development.

Understanding compounds like this one is crucial for advancing knowledge in fields such as medicinal chemistry and chemical biology. Researchers are continuously exploring complex molecules to discover new therapeutic agents and materials with enhanced functionality.

As a chemist, the exploration of such compounds opens up endless possibilities—not just in theory, but in application across diverse scientific disciplines!