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Naltrexone

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Identification
Molecular formula
C20H23NO4
CAS number
16590-41-3
IUPAC name
(1R,9S,10R)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
State
State

At room temperature, Naltrexone is a solid.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
438.00
Boiling point (Kelvin)
711.15
General information
Molecular weight
341.41g/mol
Molar mass
341.4130g/mol
Density
1.3918g/cm3
Appearence

Naltrexone appears as a white crystalline powder. It is often supplied in tablet form for clinical use. The compound is characterized by its white color, and it is usually odorless.

Comment on solubility

Solubility Insights for (1R,9S,10R)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol

The solubility of (1R,9S,10R)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol in various solvents is an intriguing aspect of its chemical behavior. Understanding its solubility can guide its applications in diverse fields. Here are some key points regarding its solubility:

  • Polarity: The presence of hydroxyl groups typically enhances solubility in polar solvents such as water.
  • Non-polar Solvents: On the other hand, this compound may exhibit limited solubility in non-polar solvents like hexane due to its complex structure.
  • Hydrogen Bonding: The ability to form hydrogen bonds can increase solubility in alcohols and similar polar solvents.
  • pH Influence: The solubility may also vary with pH, particularly in solutions that can ionize the compound.

In summary, solubility is influenced by factors like molecular structure, polarity, and the ability to engage in hydrogen bonding. Understanding these characteristics can help in the effective utilization of (1R,9S,10R)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol in different chemical environments.

Interesting facts

Interesting Facts about (1R,9S,10R)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol

(1R,9S,10R)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol is a fascinating compound with unique structural properties that have piqued the interest of chemists and biologists alike. This compound is a member of the tetracyclic class and features an intricate arrangement that lends it remarkable characteristics.

Structural Intricacies

The structure of this compound can be broken down into several notable components:

  • Tetracyclic Framework: It possesses a tetracyclic structure that creates rigid conformations, influencing its biological activity.
  • Azeatides: The incorporation of nitrogen introduces intriguing chemical behavior, as nitrogen can significantly affect the reactivity and stability of organic compounds.
  • Chiral Centers: With multiple chiral centers, this compound is capable of existing in different stereoisomeric forms, each potentially exhibiting varied biological properties.

Biological Significance

This compound and its derivatives are often explored for their pharmaceutical potential. The structural complexity can lead to interesting pharmacodynamics, making it a candidate for research into new therapeutic agents.

Quote from the Lab

As one researcher aptly put it, "The beauty of organic chemistry lies in the complexity of structures like (1R,9S,10R)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol, which serve as reminders of nature's creativity."

From medicinal applications to synthetic challenges, the study of this compound not only deepens our understanding of organic chemistry but also inspires innovations in drug design. Thus, it serves as a testament to how intricate molecular architectures can harness nature’s power in intriguing ways.