Skip to main content

Ertapenem

ADVERTISEMENT
Identification
Molecular formula
C22H25N3O7
CAS number
153832-46-3
IUPAC name
[(1S)-2-[[1-[(3R,4R,5S)-3-acetoxy-4-hydroxy-1-azabicyclo[3.1.0]hexan-2-ylidene]-2-[[1-(hydroxymethylene)-2-oxo-propyl]amino]-2-oxo-ethyl]amino]-1-[(2S)-2-methyloxiran-2-yl]-2-oxo-ethyl] 3-methoxy-5-methyl-naphthalene-1-carboxylate
State
State

At room temperature, Ertapenem is commonly available as a solid, specifically as a lyophilized powder form for intravenous administration after reconstitution.

Melting point (Celsius)
70.70
Melting point (Kelvin)
343.85
Boiling point (Celsius)
660.00
Boiling point (Kelvin)
933.15
General information
Molecular weight
497.50g/mol
Molar mass
497.4970g/mol
Density
1.3680g/cm3
Appearence

Ertapenem appears as a white to off-white crystalline powder. It has a slightly bitter taste and no odor. It is typically used in the form of its sodium salt for medical applications.

Comment on solubility

Solubility of the Compound

The solubility of the compound [(1S)-2-[[1-[(3R,4R,5S)-3-acetoxy-4-hydroxy-1-azabicyclo[3.1.0]hexan-2-ylidene]-2-[[1-(hydroxymethylene)-2-oxo-propyl]amino]-2-oxo-ethyl]amino]-1-[(2S)-2-methyloxiran-2-yl]-2-oxo-ethyl] 3-methoxy-5-methyl-naphthalene-1-carboxylate can be indicative of its potential applications and behavior in various environments. Here are some key points to consider:

  • Polar vs. Nonpolar Solubility: The presence of multiple functional groups, such as hydroxyl and ester moieties, suggests that this compound may exhibit varying solubility in polar solvents like water, as well as in nonpolar solvents like chloroform or hexane.
  • Solvent Compatibility: It is likely that the compound may show increased solubility in organic solvents due to its extensive hydrocarbon framework, while being less soluble in aqueous solutions.
    Quote: "Like dissolves like," which reflects the tendency for solubility to occur between similar types of molecular environments.
  • pH Dependency: The solubility may also be affected by pH levels, particularly if it contains protonable or ionizable groups. This could lead to different solubility characteristics in acidic versus basic conditions.
  • Temperature Effects: Higher temperatures typically increase solubility, particularly in solids, which may be true for this compound depending on its crystalline structure.

Overall, understanding the solubility of this complex compound is crucial for its practical applications, including formulation, reactivity, and biological interactions. Further experimental studies should be conducted to elucidate the precise solubility profile across different conditions.

Interesting facts

Exploration of [(1S)-2-[[1-[(3R,4R,5S)-3-acetoxy-4-hydroxy-1-azabicyclo[3.1.0]hexan-2-ylidene]-2-[[1-(hydroxymethylene)-2-oxo-propyl]amino]-2-oxo-ethyl]amino]-1-[(2S)-2-methyloxiran-2-yl]-2-oxo-ethyl] 3-methoxy-5-methyl-naphthalene-1-carboxylate

This fascinating chemical compound belongs to a class of complex organic molecules that showcase the beauty and intricacy of organic chemistry. Here are some interesting aspects that make this compound noteworthy:

  • Complex Structure: The compound features a remarkable framework that includes various functional groups such as carboxylates, amino groups, and a bicyclic structure. This complexity can lead to unique properties and reactivity.
  • Potential Biological Applications: Many compounds of similar structures exhibit biological activity. Researchers often investigate such compounds for their potential as pharmaceuticals or biological probes, especially in the field of medicinal chemistry.
  • Synthetic Challenges: The multi-step synthesis required to create this compound involves several key reactions, making it an intriguing target for organic chemists. The synthesis may include processes such as acetylation, hydroxylation, and the formation of bicyclic systems.
  • Functional Diversity: The presence of both methoxy and naphthalene moieties adds functional diversity, allowing for interactions in biological systems or in synthetic pathways.

In summary, this compound is not just an empirical formula; it embodies the beauty of organic synthesis and the potential for innovation in the field of chemistry. The ongoing exploration of such intricate compounds can lead to breakthroughs in various scientific domains.