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Oxymorphone

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Identification
Molecular formula
C17H19NO4
CAS number
76-41-5
IUPAC name
(1S,16R)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.01,13.02,7]heptadeca-2(7),12,14-trien-4-one
State
State

Oxymorphone is typically a solid at room temperature, commonly encountered in pharmaceutical formulations as a solid tablet.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.15
Boiling point (Celsius)
373.30
Boiling point (Kelvin)
646.45
General information
Molecular weight
301.34g/mol
Molar mass
301.3370g/mol
Density
1.4500g/cm3
Appearence

Oxymorphone appears as a white to off-white crystalline solid. It's typically available in the form of small crystals or powder, often used in pharmaceutical preparations.

Comment on solubility

Solubility of (1S,16R)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.01,13.02,7]heptadeca-2(7),12,14-trien-4-one

The solubility of this complex organic compound, (1S,16R)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.01,13.02,7]heptadeca-2(7),12,14-trien-4-one, can be described with several key points:

  • Nonpolar Nature: The compound's intricate ring structure and methoxy group suggest a relatively nonpolar character, which may limit its solubility in polar solvents such as water.
  • Solubility in Organic Solvents: It is likely to be more soluble in nonpolar organic solvents (e.g., hexane, acetone, or chloroform), where similar compounds often exhibit better dissolution properties.
  • Influence of Temperature: Increased temperature can potentially improve solubility in organic solvents as it can provide the energy required to weaken intermolecular interactions.
  • Hydrogen Bonding: The presence of ether linkages and nitrogen may facilitate hydrogen bonding in certain solvents, potentially increasing solubility under specific conditions.

Overall, while predicting solubility can be challenging due to the complex nature of this compound, understanding its structure and the characteristics of solvents can provide valuable insights:

  • It's essential to remember that solubility is influenced by the structure of the compound as well as the surrounding medium.
  • Furthermore, experiments will be necessary for exact solubility data, as theoretical predictions can vary significantly.

Engagement with multiple solvents and temperatures will yield a more comprehensive understanding of how and in what conditions this compound can be effectively utilized.

Interesting facts

Interesting Facts about (1S,16R)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.01,13.02,7]heptadeca-2(7),12,14-trien-4-one

This compound is a fascinating example of complex organic chemistry, showcasing the intricate nature of molecular architecture. Here are some interesting aspects that make it stand out in the world of chemical compounds:

  • Stereochemistry: The designations (1S,16R) signify specific stereoisomer configurations, indicating the spatial arrangement of atoms. This highlights the importance of stereochemistry in influencing the compound's reactivity and interaction with biological targets.
  • Structural Complexity: With a tetracyclic structure, this compound belongs to a class of molecules known for their multiple interconnected rings. This feature often leads to unique physical and chemical properties.
  • Biological Relevance: Compounds of this nature may hold significant pharmaceutical potential, often serving as leads in drug discovery. Their ability to mimic natural products can result in effective therapeutic agents.
  • Functional Groups: The presence of a methoxy group and an azetidine moiety illustrates how even subtle variations can dramatically affect a compound's behavior and properties, such as solubility and biological activity.
  • Natural Product Inspiration: Many complex organic structures like this one are inspired by natural products, where nature employs intricate chemistry to create potent bioactive compounds. Understanding their chemistry can lead to novel synthetic pathways.

This compound not only serves as a testament to the creativity and ingenuity of chemists but also emphasizes the importance of molecular design in the quest for new materials and medicine. As we explore such complex compounds, we can unlock their potential applications in various fields, from pharmacology to materials science.

Synonyms
beta-ERYTHROIDINE
466-81-9
CHEBI:27795
BRN 0036194
12,13-Didehydro-13,14-dihydro-alpha-erythroidine
(+)-beta-erythroidine
7334EOU8K5
DTXSID30196884
.BETA.-ERYTHROIDINE [MI]
4-27-00-03568 (Beilstein Handbook Reference)
.BETA.-ERYTHROIDINE, (+)-
16(15H)-Oxaerythrinan-15-one, 1,2,6,7-tetradehydro-14,17-dihydro-3-methoxy-, (3-beta)-
(1S,16R)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.01,13.02,7]heptadeca-2(7),12,14-trien-4-one
(3.BETA.)-1,2,6,7-TETRADEHYDRO-14,17-DIHYDRO-3-METHOXY-16(15H)-OXAERYTHRINAN-15-ONE
(4bS,6R)-6-methoxy-1,4,6,10,12,13-hexahydro-3H,5H-pyrano[4',3':3,4]pyrido[2,1-i]indol-3-one
1H,12H-PYRANO(4',3':3,4)PYRIDO(2,1-I)INDOL-12-ONE, 2,6,8,9,10,13-HEXAHYDRO-2-METHOXY-, (2R,13BS)-
(1S,16R)-16-methoxy-5-oxa-10-azatetracyclo(8.7.0.01,13.02,7)heptadeca-2(7),12,14-trien-4-one
(4bS,6R)-6-methoxy-1,4,6,10,12,13-hexahydro-3H,5H-pyrano(4',3':3,4)pyrido(2,1-i)indol-3-one
.BETA.-ERYTHROIDINE
DTXCID70119375
BETA-ERYTHROIDINE, (+)-
(3BETA)-1,2,6,7-TETRADEHYDRO-14,17-DIHYDRO-3-METHOXY-16(15H)-OXAERYTHRINAN-15-ONE
CHEMBL3318888
b-erythroidine
UNII-7334EOU8K5
-Erythroidine hydrochloride
SCHEMBL4216928
BDBM50497833
NS00094670
C06532
Q27103335
(2R,13BS)-2-methoxy-1,2,8,9,10,13-hexahydropyrano[4',3':3,4]pyrido[2,1-i]indol-12(6H)-one