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2-Phenylcyclopropanamine

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Identification
Molecular formula
C9H11N
CAS number
30445-13-1
IUPAC name
(1S,2R)-2-phenylcyclopropanamine
State
State

At room temperature, 2-Phenylcyclopropanamine is a liquid. It is important to handle it under appropriate conditions to maintain its purity and efficacy.

Melting point (Celsius)
-51.00
Melting point (Kelvin)
222.15
Boiling point (Celsius)
208.00
Boiling point (Kelvin)
481.15
General information
Molecular weight
133.20g/mol
Molar mass
133.2010g/mol
Density
1.0567g/cm3
Appearence

2-Phenylcyclopropanamine typically appears as a colorless to pale yellow liquid. It may also be found in other forms depending on its specific preparation and storage conditions.

Comment on solubility

Solubility of (1S,2R)-2-phenylcyclopropanamine

(1S,2R)-2-phenylcyclopropanamine is an intriguing compound, and its solubility characteristics provide valuable insights into its behavior in various environments. Understanding its solubility can be approached through several key factors:

  • Polar vs. Non-Polar: The presence of the cyclopropanamine structure influences solubility significantly. Typically, compounds with polar functional groups are more soluble in polar solvents.
  • Molecular Interactions: The aromatic phenyl group can lead to enhanced interactions with solvents through π-π stacking, potentially increasing its solubility in organic solvents.
  • Temperature Effects: Like many organic compounds, solubility may also vary with temperature, often increasing in warmer conditions as molecular motion enhances dissolution.
  • pH Influence: Given its amine nature, (1S,2R)-2-phenylcyclopropanamine may exhibit different solubility properties in acidic vs. basic environments, becoming more soluble in basic solutions where it can accept protons.

It's essential to note that while empirical data on the solubility of (1S,2R)-2-phenylcyclopropanamine may be limited, its structure suggests a balanced amphiphilicity, which can lead to moderate solubility in various organic solvents. As with many chemical compounds, conducting solubility tests under controlled conditions will provide a clearer picture of its behavior in practical applications.

In summary, the solubility of (1S,2R)-2-phenylcyclopropanamine is governed by its molecular structure and the properties of the solvent used, making it a captivating subject for further exploration in chemical assessments.

Interesting facts

Interesting Facts about (1S,2R)-2-phenylcyclopropanamine

(1S,2R)-2-phenylcyclopropanamine, a compound belonging to the class of cyclopropane derivatives, has drawn attention due to its intriguing structural features and potential pharmacological applications. Here are some captivating insights:

  • Structural Attractiveness: The cyclopropane ring in (1S,2R)-2-phenylcyclopropanamine introduces unique strain characteristics, which can impact the reactivity and interactions of the compound in biological systems.
  • Chirality Matters: The (1S,2R) configuration of this compound marks it as a chiral molecule. Chirality plays a critical role in drug development since the two enantiomers can exhibit vastly different biological activities.
  • Potential Therapeutic Uses: Studies suggest that compounds related to (1S,2R)-2-phenylcyclopropanamine may possess interesting pharmacological properties. These include potential uses in treating disorders related to the central nervous system.
  • Synthetic Challenges: The synthesis of (1S,2R)-2-phenylcyclopropanamine often involves intricate steps, highlighting the challenges associated with creating cyclopropane-containing compounds in laboratory settings. Techniques such as stereoselective synthesis and asymmetric synthesis are typically employed.
  • Foundation for Further Research: The unique properties of (1S,2R)-2-phenylcyclopropanamine create a platform for further exploration. Researchers are continually investigating derivatives and modifications to harness the compound's potential.

In summary, (1S,2R)-2-phenylcyclopropanamine is not just a simple organic compound; it epitomizes the complex interplay between structure, function, and biological activity. As a chemist or a student delving into organic chemistry, understanding such compounds can pave the way to discoveries that impact drug design and development.

Synonyms
(1S,2R)-2-phenylcyclopropanamine
(+)-Tranylcypromine
DTXSID801315454
trans-2-phenylcyclopropanamine
DTXCID801745360
988-714-7
3721-28-6
(1S,2R)-2-phenylcyclopropan-1-amine
trans-2-Phenylcyclopropylamine
(-)-Tranylcypromine
(1S,2R)-2-Phenyl-cyclopropylamine
(1S,2R)-tranylcypromine
CHEMBL257990
(1s,2r)-2-phenylcyclopropylamine
MFCD01735853
Cyclopropanamine, 2-phenyl-, (1S,2R)-
l-Tranylcypromine
2-Phenyl-1-aminocyclopropane, trans-
Cyclopropylamine, 2-phenyl-, (1S-trans)-
trans-2-phenylcyclopropan-1-amine
trans-(-)-2-Phenylcyclopropanamine
1tnl
(1S,2R)-2-phenyl-1-cyclopropanamine
MLS001306494
SCHEMBL145650
(1R)-2-Phenylcyclopropanamine
orb2277566
(1S,2R)-trans-tranylcypromine
CHEBI:94791
BRD9146
CHEBI:131511
HMS2089B04
(+)-trans-2-Phenylcyclopropylamine
BRD-9146
(1S-trans)-2-Phenylcyclopropanamine
BDBM50236898
STL563237
(+)-trans-2-Phenyl-cyclopropyl-amin
1s,2r-trans-2-phenylcyclopropylamine
AKOS027327308
(1S,2R)-(+)-2-phenylcyclopropylamine
NCGC00179670-01
AS-81089
SMR000039637
Cyclopropanamine, 2-phenyl-, trans-(+)-
CYCLOPROPYLAMINE, 2-PHENYL-, trans-
DB-234630
CS-0094394
NS00068412
EN300-222059
AN-584/40205785
BRD-K88809146-003-02-1
BRD-K88809146-003-04-7