Interesting facts
Interesting Facts about (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
This compound, with its intricate name and molecular structure, is a fascinating subject of study in the field of organic chemistry. It belongs to a class of compounds known for their unique cyclic structures and biological significance. Here are some engaging insights:
- Stereochemistry: The compound exhibits specific stereochemistry with five chiral centers, denoted by the (1S,2R,13R,14S,17R,18S) configuration. This stereochemical complexity can lead to variations in biological activity, making it essential to explore its effects thoroughly.
- Potential Applications: Compounds like this one are often investigated for their therapeutic potential. The arrangement of functional groups might suggest activity in fields such as pharmacology, particularly in drug design targeting specific enzymes or receptors.
- Structural Diversity: The pentacyclic structure provides a robust framework, which is a theme found in many naturally occurring compounds, such as steroids and alkaloids.
- Oxazole and Azabicyclo Compounds: With the presence of oxygen and nitrogen within its rings, this compound can exhibit unique reactivity and interaction with other biological molecules, opening up pathways for innovative synthetic applications.
- Research Interest: This compound is a valuable candidate for research into cyclic compounds due to its unique configuration and potential medicinal properties, which may inspire new therapeutic strategies.
The intricate nature of (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol demonstrates the beauty and complexity of organic molecules. Its exploration can lead to not only a deeper understanding of chemical structures but also potentially transformative applications in medicine and beyond.
Synonyms
danazol
Danocrine
17230-88-5
Chronogyn
Winobanin
Danol
Cyclomen
Danazolum
Ladogal
Danatrol
WIN 17757
WIN-17757
WIN 17,757
Bonzol
N29QWW3BUO
CHEBI:4315
DTXSID2022880
17alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
NSC-270916
DTXCID202880
Danoval
NSC270916
Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol,(17alpha)-
(1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4(8),5,9-trien-17-ol
Danazol Ratiopharm
(1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo(11.7.0.0^(2,10).0^(4,8).0^(14,18))icosa-4(8),5,9-trien-17-ol
(17alpha)-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
(17Alpha)-pregna-2,4-dien-20-yno(2,3-d)-isoxazol-17-ol
17Alpha-ethynyl-17beta-hydroxy-4-androsteno(2,3-d)isoxazole
1-Ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental(7,8)phenanthro(3,2-d)isoxazol-1-ol
241-270-1
Danazol, USP
Danazole
MFCD00056838
Danzol
(1R,3aS,3bR,10aR,10bS,12aS)-1-ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
Danovaol
Danokrin
NCGC00164400-01
Danogen
Danazolum [INN-Latin]
NSC 270916
(1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
Danazol (1.0 mg/mL in acetonitrile)
Danocrine (TN)
SMR000058321
CCRIS 6747
EINECS 241-270-1
UNII-N29QWW3BUO
Vasaloc
17-alpha-Pregn-4-en-20-yno(2,3-d)isoxazol-17-ol
Optina
17-alpha-2,4-Pregnadien-20-yno(2,3-d)isoxazol-17-ol
Danazol?
Win 17, 757
Prestwick_150
Danazol (Standard)
CAS-17230-88-5
Danazol [USAN:USP:INN:BAN:JAN]
DANAZOL [VANDF]
ethynyl(dimethyl)[?]ol
2,3-Isoxazolethisterone
DANAZOL [USAN]
DANAZOL [INN]
DANAZOL [JAN]
DANAZOL [MI]
DANAZOL [MART.]
Prestwick0_000105
Prestwick1_000105
Prestwick2_000105
Prestwick3_000105
DANAZOL [USP-RS]
DANAZOL [WHO-DD]
CHEMBL1479
SCHEMBL21107
BSPBio_000090
MLS001066617
MLS001306473
Danazol (JP17/USP/INN)
DANAZOL [ORANGE BOOK]
SPBio_002029
BPBio1_000100
GTPL6942
DANAZOL [USP MONOGRAPH]
HY-B1029R
MSK2202
Win-17,757
POZRVZJJTULAOH-LHZXLZLDSA-N
GLXC-21458
HMS1568E12
HMS2090A22
HMS2095E12
HMS2231M08
HMS3259M10
HMS3712E12
[1,2]oxazolo[4',5':2,3]-17alpha-pregn-4-en-20-yn-17-ol
17.Alpha.-Pregna-2, {4-dien-20-yno[2,3-d]isoxazol-17-ol}
BCP11914
HY-B1029
Tox21_112114
Tox21_301940
BDBM50423541
s9506
AKOS015961192
Tox21_112114_1
AC-6836
CCG-220105
CS-4547
Danazol 100 microg/mL in Acetonitrile
DB01406
NC00557
NCGC00179665-01
NCGC00179665-02
NCGC00179665-04
NCGC00255335-01
1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
AS-13035
DA-72548
FD156781
NS00004972
C06938
D00289
Q419652
SR-01000760722
SR-05000000445
SR-01000760722-2
SR-05000000445-2
17a-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol
BRD-K48970916-001-03-0
(17a)-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol
17a-Pregna-2,4-dien-20-yne-[2,3-d]isoxazole-17b-ol
17 alpha-pregna-2,4-dien-20-yno[2,3-D] isoxazol-17 beta-ol
17.ALPHA.-PREGNA-2,4-DIEN-20-YNO(2,3)-DISOXAZOL-17-OL
Pregna-2, {4-dien-20-yno[2,3-d]isoxazol-17-ol,} (17.alpha.)-
PREGNA-2,4-DIEN-20-YNO(2,3-D)ISOXAZOL-17-OL,(17.ALPHA.)-
(1R,3aS,3bR,10aR,10bS,12aS)-1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d][1,2]oxazol-1-ol
1-ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-Cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
1H-Cyclopenta[7,8]phenanthro[3,2-d]isoxazole- pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol deriv.
Solubility of (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
The solubility of this compound is influenced by its complex molecular structure, which can result in varied interactions with solvents. Generally, compounds with such intricate architectures may demonstrate:
In summary, while predicting the exact solubility of such a compound can be challenging, one might observe that:
As with many complex molecules, experimental verification is essential, and consultation with solubility parameters can provide additional insights into this compound's behavior in different environments.