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Tropicamide hydrobromide

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Identification
Molecular formula
C17H22BrNO4
CAS number
54-64-8
IUPAC name
[(1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate;hydrobromide
State
State
At room temperature, tropicamide hydrobromide is in a solid state, typically as a crystalline powder.
Melting point (Celsius)
257.00
Melting point (Kelvin)
530.15
Boiling point (Celsius)
222.00
Boiling point (Kelvin)
495.15
General information
Molecular weight
385.29g/mol
Molar mass
385.2940g/mol
Density
1.3000g/cm3
Appearence

Tropicamide hydrobromide appears as a crystalline powder which is often white or off-white in color.

Comment on solubility

Solubility of [(1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate; hydrobromide

The solubility of the compound [(1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate; hydrobromide can be influenced by various factors. Understanding its solubility is crucial for applications in chemical synthesis and pharmaceutical formulations.

Key Factors Affecting Solubility

  • Polarity: The presence of polar and nonpolar groups in the molecular structure affects how well the compound dissolves in various solvents.
  • Temperature: Generally, an increase in temperature can enhance solubility, particularly for solid compounds dissolving in liquids.
  • pH Level: The hydrobromide form suggests that the compound may be soluble in acidic conditions. Thus, variations in pH can lead to changes in solubility behavior.
  • Solvent Type: Water, organic solvents (like ethanol or methanol), and their polarities play a significant role in the dissolution process.

Considering the complex structure of this compound, it may exhibit distinct solubility traits:

  • Potential solubility in organic solvents due to hydrophobic regions.
  • Possible limited solubility in water, given the complexity of its structure and the presence of hydrophobic moieties.

In conclusion, the solubility profile of this compound is likely to be multi-faceted, requiring specific conditions to achieve optimal dissolution. Further empirical testing will be essential to ascertain precise solubility levels across various environments.

Interesting facts

Interesting Facts about [(1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate;hydrobromide

This compound presents a fascinating intersection of chemistry and pharmacology, highlighting the intricate design involved in drug development. Here are some interesting insights:

  • Complex Structure: The compound features a unique tricyclic framework, coupled with an oxa and azatricyclo system, showcasing the versatility and complexity of organic synthesis.
  • Chirality: The stereochemistry denoted by its (1S,2R,4S,5S) configuration reveals its chirality, which is critical in determining the compound's biological activity and interaction with biological receptors.
  • Potential Applications: Compounds with similar structures are often explored for their medicinal properties. This compound could potentially serve as a lead in developing new therapeutic agents, particularly in the fields of neuropharmacology and analgesics.
  • Hydrobromide Salt Formation: The hydrobromide form of this compound enhances its solubility and stability, which is crucial for biological testing and pharmaceutical formulation.
  • Role of Esters: The inclusion of a 3-hydroxy-2-phenyl-propanoate moiety suggests possible esterification or prodrug properties, which could improve bioavailability or targeting specific pathways in the body.

As you explore more about this compound, keep in mind the profound impact structural diversity has on pharmacological effects. To quote a renowned chemist, “The beauty of chemistry lies in the endless possibilities of structural variation, each leading to unique functionalities.”

In summary, the study of [(1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate;hydrobromide not only delves into its intricate molecular architecture but also inspires future research towards therapeutic innovations.

Synonyms
DTXSID20986312
9-Methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-7-yl 3-hydroxy-2-phenylpropanoate--hydrogen bromide (1/1)