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(1S,2S)-2-phenoxycyclopropanamine

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Identification
Molecular formula
C9H13NO
CAS number
22523-58-0
IUPAC name
(1S,2S)-2-phenoxycyclopropanamine
State
State

The compound is in a liquid state at room temperature. It is an organic compound that can be used in various chemical syntheses.

Melting point (Celsius)
-15.00
Melting point (Kelvin)
258.15
Boiling point (Celsius)
136.50
Boiling point (Kelvin)
409.65
General information
Molecular weight
163.20g/mol
Molar mass
163.2040g/mol
Density
1.0341g/cm3
Appearence

(1S,2S)-2-phenoxycyclopropanamine typically appears as a colorless to pale yellow liquid. Its appearance can vary slightly depending on purity and concentration, but it generally maintains a clear, liquid form.

Comment on solubility

Solubility of (1S,2S)-2-phenoxycyclopropanamine

(1S,2S)-2-phenoxycyclopropanamine is a compound that exhibits unique solubility characteristics due to its structural features. The following aspects are noteworthy:

  • Polar Interactions: The presence of the phenoxy group contributes to potential polar interactions with solvents, which may enhance solubility in polar solvents.
  • Stereochemistry: The (1S,2S) configuration may influence how this compound interacts at the molecular level, impacting its solubility profile.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents compared to water, making it compatible with various formulations in pharmaceutical applications.

In summary, while (1S,2S)-2-phenoxycyclopropanamine's solubility can be expected to be moderate in common organic solvents, its behavior in aqueous solutions may be limited due to its hydrophobic cyclopropane ring. Understanding these solubility dynamics is essential for effective application and formulation of this compound in research and industry.

Interesting facts

Interesting Facts About (1S,2S)-2-phenoxycyclopropanamine

(1S,2S)-2-phenoxycyclopropanamine is a fascinating compound with several noteworthy attributes:

  • Unique Structure: The cyclopropane ring in this compound presents a strained, three-membered ring structure, which often leads to intriguing chemical behavior.
  • Use in Drug Development: Compounds containing the amine functional group are frequently explored for their potential as pharmaceuticals. The unique features of 2-phenoxycyclopropanamine make it a candidate for drug development in treatments targeting neurological disorders.
  • Stereochemistry: The (1S,2S) designation indicates specific stereochemistry that can significantly affect the biological activity of this compound, making stereochemical consideration important in medicinal chemistry.
  • Potential Applications: Due to its distinctive properties, it might be utilized as an intermediate in organic synthesis, potentially leading to innovations in various chemical applications.

As a chemistry student or enthusiast, understanding the implications of the structure and properties of (1S,2S)-2-phenoxycyclopropanamine is crucial. As an example, compounds with enriched stereocenters often exhibit chiral selectivity in biological interactions, which could lead to more effective therapeutic agents.

Additionally, the phenoxy group linked to the cyclopropane enhances the compound's potential interactions with biological systems, creating opportunities for detailed research into structure-activity relationships (SAR).

Overall, the study of (1S,2S)-2-phenoxycyclopropanamine opens doors to exploring new avenues in both synthetic chemistry and therapeutic applications.

Synonyms
trans-2-Phenoxycyclopropylamine
(1S,2S)-2-phenoxycyclopropan-1-amine
CYCLOPROPYLAMINE, 2-PHENOXY-, trans-
CHEMBL3330327
AKOS006361928