Atropine nitrate | Solubility of Things

Identification

Molecular formula

C₁₇H₂₃NO₃ • HNO₃

CAS number

142-63-2

IUPAC name

[(1S,2S,4R,5S)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate;nitrate

State

At room temperature, atropine nitrate is in solid form. It is stable under normal conditions of storage and handling.

Melting point (Celsius)

189.00

Melting point (Kelvin)

462.15

Boiling point (Celsius)

250.00

Boiling point (Kelvin)

523.15

General information

Molecular weight

347.39g/mol

Molar mass

347.3870g/mol

Density

1.4400g/cm³

Appearence

Atropine nitrate typically appears as a white crystalline powder. It is highly soluble in water and features a characteristic odor.

Comment on solubility

Solubility of [(1S,2S,4R,5S)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate;nitrate

The solubility of the compound [(1S,2S,4R,5S)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate;nitrate is influenced by several key factors:

Molecular Structure: The presence of both hydroxy and nitrile functional groups suggests a degree of polarity, which can enhance solubility in polar solvents such as water.
Hydrophobic Regions: The introduction of large phenyl groups may limit solubility in non-polar solvents, impacting its overall solubility profile.
pH Influence: As a quaternary ammonium compound, its solubility could increase in acidic or alkali solutions where ionic interactions can occur, facilitating dissolution.

This compound's solubility behavior can be described as follows:

High solubility in polar solvents (e.g., water, alcohols) due to ionic and hydrogen bonding capabilities.

Limited solubility in non-polar solvents due to hydrophobic phenyl substituents.

Dependence on temperature: Increased temperature may enhance solubility due to greater kinetic energy.

Overall, the compound is likely to exhibit a fascinating balance between solubility in polar environments while facing challenges in achieving solubility within non-polar media. Understanding these solubility characteristics is crucial for practical applications and further research.

Interesting facts

Interesting Facts about [(1S,2S,4R,5S)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] 3-hydroxy-2-phenyl-propanoate; nitrate

This compound, with an intriguing and complex structure, belongs to the category of quaternary ammonium salts, which are known for their unique properties and applications. Here are some interesting insights into this compound:

Chirality and Stereochemistry: The compound exhibits multiple chiral centers, making it significant in the field of stereochemistry. The specific stereochemistry not only influences the physical properties of the compound but also its interactions in biological systems.

Biological Relevance: Compounds with similar structural frameworks have been studied for their potential activities in pharmacology and medicinal chemistry. This type of structure could mimic natural compounds, leading to potential therapeutic applications.

Ring Systems: The bicyclic nature of the compound, hinted at by the "tricyclo" nomenclature, suggests interesting reactivity patterns and could confer stability or reactivity advantages in certain chemical environments.

Functional Groups: The presence of an oxa- group (indicating an oxygen atom within the cyclic structure) and a phenyl group signifies potential interactions that can be exploited in material science and organic synthesis.

Reactivity: Nitrate groups are known to impart specific reactivity to organic compounds, often leading to enhanced electrophilicity, which can be beneficial in various chemical pathways.

In summary, this compound is a fascinating example of synthetic chemistry combining complexity with potential biological significance. The study of such compounds enriches our understanding of both the fundamental properties of chemical substances and their real-world applications. Researchers continue to explore how the nuanced details of molecular structure can lead to breakthroughs in technology and medicine.