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Alpha-cyclodextrin

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Identification
Molecular formula
C36H60O30
CAS number
10016-20-3
IUPAC name
(1S,3R,6S,8R,11S,13R,16S,18R,21S,23R,26S,28R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol
State
State

Alpha-cyclodextrin is typically a solid at room temperature, existing in a crystalline state. It is stable under ambient conditions and does not easily degrade, making it suitable for various industrial and pharmaceutical applications.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
972.84g/mol
Molar mass
972.8400g/mol
Density
1.4500g/cm3
Appearence

Alpha-cyclodextrin appears as a white crystalline powder with no distinctive odor. It is hygroscopic, meaning it can absorb moisture from the air. The crystalline structure contributes to its high stability and robust properties in various applications.

Comment on solubility

Solubility of (1S,3R,6S,8R,11S,13R,16S,18R,21S,23R,26S,28R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol

This highly complex compound, with the chemical formula C36H60O30, exhibits fascinating solubility characteristics largely due to its extensive hydrophilic (water-attracting) functional groups. The presence of numerous hydroxymethyl groups in its structure significantly increases its solubility in aqueous environments. Below are some key aspects regarding its solubility:

  • Hydrophilicity: The hydroxymethyl groups (-CH2OH) enhance intermolecular interactions with water, promoting dissolution.
  • Solvent Interaction: This compound is expected to be soluble in polar solvents, particularly water, while its solubility in non-polar solvents may be limited.
  • Concentration Dependency: The solubility may vary with concentration; at higher concentrations, the solute-solvent interactions can lead to saturation effects.
  • Temperature Influence: Like many compounds, solubility may increase with temperature due to enhanced molecular motion.

In summary, due to its complex structure filled with functional hydroxymethyl groups, this compound demonstrates high solubility in polar solvents such as water but may exhibit limited solubility in non-polar environments. As a general rule, compounds with >10% hydroxyl functional groups tend to have higher solubility in water, thus, this compound can be predicted to align with that trend.

Interesting facts

Interesting Facts about the Compound

The compound known as (1S,3R,6S,8R,11S,13R,16S,18R,21S,23R,26S,28R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol is an intricate chemical structure with substantial significance in various scientific fields. Below are some captivating facts:

  • Complex Structure: This compound features a remarkable multi-cyclic architecture, comprising more than 30 hydroxymethyl functional groups, which contributes to its unique chemical properties.
  • Potential Applications: Compounds with similar structural motifs are often explored for applications in drug delivery systems, nanotechnology, and materials science due to their ability to form complex geometries in solution.
  • Stereochemistry: The presence of multiple stereocenters indicates not only the compound's chirality but also its potential for diverse biological interactions, making it an intriguing subject of study in stereochemistry.
  • Natural Inspirations: Many complex organic compounds like this one are inspired by natural products, showcasing how nature's designs can lead to advancements in synthetic chemistry.

This compound exemplifies the intersection of organic synthesis, molecular design, and functional material science. As we continue to explore such complex molecules, we unlock new pathways for innovation and application in the world of chemistry.

Synonyms
MFCD00078207
CHEMBL2373320
SCHEMBL12459493
(1S,3R,6S,8R,11S,13R,16S,18R,21S,23R,26S,28R)-5,10,15,20,25,30-Hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol