Oxycodone Hydrochloride | Solubility of Things

Identification

Molecular formula

C₁₈H₂₅NO₂Cl

CAS number

124-90-3

IUPAC name

[(1S,4R)-4-acetoxy-1-methyl-3,3-diphenyl-hexyl]-dimethyl-ammonium;chloride

State

At room temperature, it is in a solid state.

Melting point (Celsius)

150.00

Melting point (Kelvin)

423.15

Boiling point (Celsius)

317.00

Boiling point (Kelvin)

590.15

General information

Molecular weight

375.94g/mol

Molar mass

375.9380g/mol

Density

1.2000g/cm³

Appearence

Oxycodone hydrochloride appears as a white, crystalline powder that is highly soluble in water. It is typically free from any odors and retains a slightly bitter taste.

Comment on solubility

Solubility of [(1S,4R)-4-acetoxy-1-methyl-3,3-diphenyl-hexyl]-dimethyl-ammonium; chloride

The solubility of the compound [(1S,4R)-4-acetoxy-1-methyl-3,3-diphenyl-hexyl]-dimethyl-ammonium; chloride can be quite intriguing and is influenced by several factors:

Polarity: The presence of a quaternary ammonium group often indicates that this compound may exhibit ionic characteristics, which can enhance solubility in polar solvents, particularly water.
Functional Groups: The acetoxy and phenyl groups in the molecular structure can introduce steric hindrance, which may affect solubility by limiting the ability of the solvent to interact with the compound.
Solvent Interaction: To maximize solubility, it is often beneficial to consider solvents with similar polarity or functional groups.
Temperature Variability: Solubility can also vary significantly with temperature; increased temperature generally enhances solubility for many compounds.
Concentration Effects: High concentrations of such a compound could lead to decreased solubility due to solute-solute interactions.

In summary, while the compound [(1S,4R)-4-acetoxy-1-methyl-3,3-diphenyl-hexyl]-dimethyl-ammonium; chloride may exhibit a tendency towards solubility in polar environments, the specific solubility characteristics are highly dependent on a multitude of factors, leading to complex behaviors in various conditions. Understanding these nuances is key in predicting its solubility in practical applications.

Interesting facts

Interesting Facts About [(1S,4R)-4-acetoxy-1-methyl-3,3-diphenyl-hexyl]-dimethyl-ammonium;chloride

This compound is a fascinating example of a quaternary ammonium salt, which showcases the intriguing interplay between organic chemistry and medicinal applications. It possesses unique structural features that not only define its chemical behavior but also significantly influence its biological activity.

Key Features

Chirality: The presence of stereocenters makes this compound a chiral molecule, allowing it to exhibit different optical activities. This is critical in pharmaceutical chemistry, where the efficacy and safety of drugs can vary between enantiomers.
Ammonium Ion: The quaternary ammonium structure contributes to its solubility and ability to interact with biological membranes. This property is often exploited in drug design and delivery systems.
Acetoxy Group: The acetoxy functional group enhances the compound’s reactivity, making it a potential candidate for various biochemical transformations.

Applications

Compounds of this nature are widely studied for their:

Antimicrobial Activity: Quaternary ammonium salts are known for exhibiting antimicrobial properties, making them valuable in disinfectants and antiseptics.
Drug Delivery Systems: Their ability to cross cell membranes efficiently is exploited in formulating effective drug delivery vehicles.
Biological Research: Such compounds can serve as valuable tools in biological studies due to their interactions with various cellular components.

Conclusion

In conclusion, [(1S,4R)-4-acetoxy-1-methyl-3,3-diphenyl-hexyl]-dimethyl-ammonium;chloride is not just a remarkable chemical entity but also a delightful subject of study for chemists and researchers alike. With its diverse applications and complex structure, it underscores the profound connection between chemistry and real-world applications.