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Propiverine

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Identification
Molecular formula
C23H29NO2
CAS number
60569-19-9
IUPAC name
[(1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate
State
State

State: Solid at room temperature. It is stable and typically found in powder form for pharmaceutical use.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
392.00
Boiling point (Kelvin)
665.15
General information
Molecular weight
339.48g/mol
Molar mass
339.4710g/mol
Density
1.0675g/cm3
Appearence

Propiverine is a white to off-white crystalline powder. It is typically odorless. Due to its complex molecular structure with diphenyl rings, its crystals may appear to have a shiny finish under light.

Comment on solubility

Solubility of [(1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate

The solubility of [(1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate can be quite intriguing due to its complex structure. Being an ester derivative, it exhibits some key characteristics related to solubility:

  • Polarity: The presence of a dimethylamino group can contribute to both polar and nonpolar characteristics, making it potentially soluble in various solvents.
  • Hydrophobic and Hydrophilic Balance: The bulky diphenyl and ethyl groups enhance hydrophobicity, whereas the acetate functional group can introduce some polar interactions.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents (like ethanol or chloroform) than in water due to its hydrophobic nature.
  • Temperature Effect: Solubility might increase with temperature, as is common with many organic compounds.

In summary, while the solubility profile of this compound is influenced by its unique structure, it can generally be anticipated that:

  1. It will be soluble in polar organic solvents.
  2. Its solubility in water may be limited due to its hydrophobic segments.
  3. Understanding solubility requires considering not just the molecular structure but also the environment in which the compound is placed.

As with many organic compounds, experimental data on solubility in various solvents is essential for a definitive understanding.

Interesting facts

Interesting Facts About [(1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] Acetate

This compound is notable for its unique structural features and potential applications across various fields of chemistry. Here are some fascinating aspects of this organic compound:

  • Stereochemistry: The presence of stereocenters at specific positions illustrates the importance of stereochemistry in organic compounds. The designation of (1S,4S) indicates that the compound could exhibit distinct properties compared to its stereoisomers.
  • Dimethylamino Group: The dimethylamino functional group provides the compound with intriguing electronic properties, facilitating its use in various synthetic pathways and potentially influencing its biological activities.
  • Diphenyl Substitution: The presence of two phenyl groups in the structure significantly enhances the compound's lipophilicity, making it relevant in medicinal chemistry, particularly in the development of pharmaceuticals.
  • Customizable Properties: The versatility of this compound can be attributed to the varied functional groups attached. This provides avenues for chemists to modify its reactivity and interaction with biological systems.
  • Research Potential: Ongoing research may uncover more about this compound's potential drug-like properties, making it a candidate for further investigation in fields such as pharmacology and biochemistry.

As a student or a scientist, understanding the intricacies of such compounds enriches your knowledge and assists in the exploration of innovative chemical solutions. The complexities of [(1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate serve as a reminder of the endless possibilities within the realm of organic chemistry.

Synonyms
Levomethadyl acetate
Levacetylmethadol
Orlaam
levo-Alphacetylmethadol
(-)-alpha-Acetylmethadol
levo-alpha-Acetylmethadol
alpha-l-Acetylmethadol
Levacetylmethadol [INN]
alpha-(-)-Acetylmethadol
N-alpha-Acetylmethadol
Levacetilmetadol [INN-Spanish]
Levacetylmethadolum [INN-Latin]
l-alpha-Acetylmethadol
Levoacetyl methadol
Levomethadyl acetate [USAN]
LAA-M
Levacetylmethadol (INN)
[(3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate
Levomethadyl acetate (USAN)
UNII-R3B637Y991
Orlaam (TN)
DTXSID3023211
LEVACETYLMETHADOL [MART.]
LEVOMETHADYL ACETATE [MI]
LEVACETYLMETHADOL [WHO-DD]
LEVACETYLMETHADOL [EMA EPAR]
(3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-2-yl acetate
(3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate
Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate(ester), (-)
Levacetilmetadol (INN-Spanish)
Levacetylmethadolum (INN-Latin)
LEVACETYLMETHADOL (MART.)
(1S,4S)-(6-DIMETHYLAMINO-4,4-DIPHENYL-HEPTAN-3-YL) ACETATE
ORLAAM (Salt/Mix)
BENZENEETHANOL, .BETA.-(2-(DIMETHYLAMINO)PROPYL)-.ALPHA.-ETHYL-.BETA.-PHENYL-, ACETATE (ESTER), (-)-
l-.alpha.-Acetylmethadol
Levo-.alpha.-acetylmethadol
MK 790 (Salt/Mix)
(-)-.alpha.-Acetylmethadol
((3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl) acetate
Levoacetylmethadol
1-a-Acetylmethadol
Benzeneethanol, B-(2-(Dimethylamino)Propyl)-Alpha-Ethyl-Beta-Phenyl-, Acetate (Ester), (-)-
Benzeneethanol, B-[2-(Dimethylamino)Propyl]-Alpha-Ethyl-Beta-Phenyl-, Acetate (Ester), (-)-
Levomethadyl acetate hydrochloride (Salt/Mix)
(-)-a-Acetylmethadol
Levomethadyl acetic acid
Levo alpha Acetylmethadol
DTXCID403211
levomethadyl acetate hydrochlorid
4-(Dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate, (3S,6S)-(-)-
N07BC03
(1S,4S)-4-(Dimethylamino)-1-ethyl-2,2-diphenylpentyl acetic acid
Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate (ester), (-)-
(3r,6r)-3-acetoxy-6-dimethylamino-4,4-diphenylheptane
nor-laam
xbmivrrwgcybtq-uhfffaoysa-n
LAAM
Levomethadyl
1-alpha-Acetylmethadol
levo-Methadyl acetate
1477-40-3
Levacetilmetadol
Levacetylmethadolum
DEA No. 9648
(-)-6-(Dimethylamino)-4,4-diphenyl-3-heptanol acetate (ester)
CHEBI:6441
(1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate
R3B637Y991
Benzeneethanol, beta-((2S)-2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate (ester), (alphaS)-
Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate (ester), (S-(R*,R*))-
34433-66-4
benzeneethanol, beta-[(2S)-2-(dimethylamino)propyl]-alpha-ethyl-beta-phenyl-, acetate (ester), (alphaS)-
Benzeneethanol, beta-[2-(dimethylamino)propyl]-alpha-ethyl-beta-phenyl-, acetate (ester), [S-(R*,R*)]-
CHEMBL1514
BIDD:PXR0155
SCHEMBL93805
BIDD:GT0373
GTPL7212
DB01227
NCGC00247347-01
[S-(R*,R*)]-beta-[2-Dimethylamino)propyl]-alpha-ethyl-beta-phenylbenzeneethanol acetate (ester)
NS00068555
C08012
D04716
Q411799
3-Heptanol, 6-(dimethylamino)-4,4-diphenyl-, acetate (ester), (3S,6S)-(-)- (8CI)
Benzeneethanol, beta-[(2S)-2-(dimethylamino)propyl]-alpha-ethyl-beta-phenyl-, acetate (ester), (alphaS)- (9CI)