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Cefotaxime

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Identification
Molecular formula
C16H17N5O7S2
CAS number
63527-52-6
IUPAC name
2-[[1-(2-aminothiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfo-azetidin-3-yl)amino]-2-oxo-ethylidene]amino]oxy-2-methyl-propanoic acid
State
State

At room temperature, Cefotaxime is in a solid state, typically existing as a crystalline powder which is insoluble in water.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
455.45g/mol
Molar mass
455.4500g/mol
Density
1.5700g/cm3
Appearence

Cefotaxime usually appears as a white or slightly yellow crystalline powder.

Comment on solubility

Solubility of 2-[[1-(2-aminothiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfo-azetidin-3-yl)amino]-2-oxo-ethylidene]amino]oxy-2-methyl-propanoic acid

The solubility of the compound 2-[[1-(2-aminothiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfo-azetidin-3-yl)amino]-2-oxo-ethylidene]amino]oxy-2-methyl-propanoic acid (C16H17N5O7S2) can be influenced by several factors, given its complex molecular structure. Understanding the solubility is essential for applications in pharmaceuticals and biological systems. Here are some key points to consider:

  • Polarity: The presence of multiple functional groups, including amino, sulfonic acid, and carboxylic acid, hints at a largely polar molecule, which may enhance its solubility in aqueous solutions.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to amino and hydroxyl groups can increase solubility in polar solvents.
  • pH Effect: As a carboxylic acid, its solubility may significantly vary with pH; higher solubility is often observed in basic solutions where deprotonation occurs.
  • Solvent Interaction: Solubility often depends on the solvent used; it may be more soluble in polar solvents than in nonpolar solvents.

In summary, while the specific solubility data for this compound might require experimental validation, it is anticipated to exhibit good solubility characteristics in polar environments due to its functional group composition. Observations and experimental data will provide further insights into its thermodynamic behavior and interactions in various solvents.

Interesting facts

Interesting Facts About 2-[[1-(2-aminothiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfo-azetidin-3-yl)amino]-2-oxo-ethylidene]amino]oxy-2-methyl-propanoic acid

This compound, known for its complex structure, is of great interest in the fields of medicinal chemistry and pharmacology. It showcases the beauty of organic synthesis, particularly in its multifaceted functionality that contributes to its biological activity.

Key Characteristics:

  • Multi-functional Groups: The molecule includes various functional groups such as thiazole, sulfonyl, and amine groups, which may interact synergistically.
  • Potential Antimicrobial Activity: Compounds containing thiazole structures have been observed to exhibit antimicrobial properties, making this compound a potential candidate for further research in combating infections.
  • Inhibitory Actions: The design of this compound suggests it could serve as a potent inhibitor or modulator in biological systems, especially in relation to enzymes or receptor pathways.
  • Complex Structure: Its intricate structure represents a challenge in both synthesis and characterization, making it a valuable compound for training in synthetic organic chemistry.

The design of compounds like this reflects a trend in drug development where researchers strive for selectivity and efficacy, aiming to create drugs that target specific pathways with minimal side effects. The potential applications of this compound are vast, resulting in a rich area of exploration for future research.

As students and scientists delve into the properties and applications of this compound, they encounter an exemplary model of how modern chemistry can influence fields such as pharmaceuticals and biotechnology. As the late chemist Richard Feynman famously said, "What I cannot create, I do not understand." Thus, the synthesis and study of such a compound enhance our understanding of molecular interactions and biochemistry.

Synonyms
aztreonam
78110-38-0
2-[[1-(2-amino-1,3-thiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
85506-30-5
Aztreonam-d6
1127452-94-1
SQ-26,776
DTXSID10861003
WZPBZJONDBGPKJ-UHFFFAOYSA-N
HMS3373D13
HMS3654F18
HMS3748K17
BCP01737
CVB45294
SY129274
[2S-[2a,3b ]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid
2-({[(2-amino-1,3-thiazol-4-yl)[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)carbamoyl]methylidene]amino}oxy)-2-methylpropanoic acid
2-[({1-(2-amino-1,3-thiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino]-2-oxoethylidene}amino)oxy]-2-methylpropanoic acid