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Brompheniramine

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Identification
Molecular formula
C16H19BrN2O
CAS number
86-22-6
IUPAC name
2-[1-(4-bromophenyl)-1-phenyl-ethoxy]-N,N-dimethyl-ethanamine
State
State

At room temperature, brompheniramine is typically in a solid state, appearing as a crystalline powder. It is stable under ordinary conditions of use and storage.

Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
305.20
Boiling point (Kelvin)
578.35
General information
Molecular weight
319.24g/mol
Molar mass
319.2600g/mol
Density
1.3550g/cm3
Appearence

Brompheniramine typically appears as a white or slightly yellow, crystalline powder. It may have a faint odor and is soluble in water, methanol, chloroform, and alcohol.

Comment on solubility

Solubility of 2-[1-(4-bromophenyl)-1-phenyl-ethoxy]-N,N-dimethyl-ethanamine

The solubility of 2-[1-(4-bromophenyl)-1-phenyl-ethoxy]-N,N-dimethyl-ethanamine is influenced by various factors and can be characterized as follows:

  • Polar vs. Non-Polar: This compound exhibits a combination of polar and non-polar characteristics due to its aromatic rings and ethoxy group, making it primarily sparingly soluble in water.
  • Solvent Compatibility: It tends to be more soluble in organic solvents such as ethanol, chloroform, and acetone due to its hydrophobic segments.
  • Temperature Dependence: Like many organic compounds, its solubility can increase with temperature, allowing for better dissolution in warmer solvents.
  • pH Factors: The solubility may also vary with pH; for instance, it may become more soluble in acidic or basic solutions depending on the protonation state of the amine group.

As a general rule, functional groups significantly determine the solubility characteristics of a compound. In the case of 2-[1-(4-bromophenyl)-1-phenyl-ethoxy]-N,N-dimethyl-ethanamine, the presence of a branched amine structure alongside the aromatic moieties creates a unique balance of solubility traits.

Understanding these solubility behaviors is crucial for applications ranging from drug formulation to industrial processing.

Interesting facts

Interesting Facts about 2-[1-(4-bromophenyl)-1-phenyl-ethoxy]-N,N-dimethyl-ethanamine

This fascinating compound, known for its complex structure, offers a myriad of opportunities for scientific exploration and application. Here are some intriguing aspects of this compound:

  • Structural Diversity: The presence of both bromine and ethoxy functional groups in its structure allows for diverse chemical behavior. The 4-bromophenyl group can significantly affect the compound's reactivity and interactions with biological targets.
  • Potential Applications: Compounds with similar structures often find uses in pharmaceuticals. They may serve as precursors in the synthesis of biologically active molecules or as potential therapeutic agents in treating various diseases.
  • Mechanistic Studies: Researchers often study such compounds to understand their pharmacodynamics and pharmacokinetics. Their behavior in biological systems can help inform drug design and efficacy.
  • Market Value: The compound may hold potential significance within the chemical industry, especially in the development of new materials or medicinal products, making it a subject of interest for chemists and industry professionals alike.
  • Research Trends: Ongoing studies may examine the compound's derivatives to enhance potency or reduce side effects, reflecting the evolving nature of chemical research.

In summary, 2-[1-(4-bromophenyl)-1-phenyl-ethoxy]-N,N-dimethyl-ethanamine stands out due to its intricate structure and potential for various applications, making it a compound of great interest in the fields of organic and medicinal chemistry.

Synonyms
Embramine
3565-72-8
Embramina
mebrophenhydramine
Embraminum [INN-Latin]
Embraminum
Embramine [INN:BAN]
Embramina [INN-Spanish]
UNII-HH0KD7Z416
Embramine (INN)
BRN 2335383
HH0KD7Z416
EMBRAMINE [INN]
EMBRAMINE [MI]
EMBRAMINE [WHO-DD]
DTXSID60863198
Ethanamine, 2-(1-(4-bromophenyl)-1-phenylethoxy)-N,N-dimethyl-
2-((p-Bromo-alpha-methyl-alpha-phenylbenzyl)oxy)-N,N-dimethylethylamine
2-((p-Bromo-.alpha.-methyl-.alpha.-phenylbenzyl)oxy)-N,N-dimethylethylamine
Embraminum (INN-Latin)
Embramina (INN-Spanish)
2-(p-Bromo-alpha-methyl-alpha-phenylbenzyloxy)-N,N-dimethylethyl amine
Ethylamine, 2-((p-bromo-.alpha.-methyl-.alpha.-phenylbenzyl)oxy)-N,N-dimethyl-
ETHYLAMINE, 2-((p-BROMO-alpha-METHYL-alpha-PHENYLBENZYL)OXY)-N,N-DIMETHYL-
DTXCID60811856
Ethanamine, 2-(1-(4-bromophenyl)-1-phenylethoxy)-N,N-dimethyl-(9CI)
4-06-00-04722 (beilstein handbook reference)
ursrsksnfpukgh-uhfffaoysa-n
2-(1-(4-Bromophenyl)-1-phenylethoxy)-N,N-dimethylethanamine
2-[1-(4-bromophenyl)-1-phenylethoxy]-N,N-dimethylethanamine
2-[1-(4-Bromophenyl)-1-phenylethoxy]-N,N-dimethylethanamine; 1-(2-Dimethylaminoethoxy)-1-(p-bromophenyl)-1-phenylethane; 2-[(p-Bromo-alpha-methyl-alpha-phenylbenzyl)oxy]-N,N-dimethyl Ethylamine
SCHEMBL28365
CHEMBL2110819
CHEBI:135472
DAA56572
HY-U00132
AKOS016014908
CS-7169
SB82947
DA-52869
D07889
EN300-834031
Q5370168
Z2574931930
{2-[1-(4-bromophenyl)-1-phenylethoxy]ethyl}dimethylamine
2-(1-(4-Bromophenyl)-1-phenylethoxy)-N,N-dimethylethan-1-amine