Interesting facts
Interesting Facts about 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid is a fascinating compound that showcases the complexities of organic chemistry.
Key Features:
- Structural Diversity: This compound contains an indole ring, which is well-known in the biology of various natural products and pharmaceuticals.
- Chlorine Atoms: The presence of a chlorine atom enhances both the lipophilicity and biological activity of the compound, often leading to increased potency in medicinal chemistry.
- Methoxy Group: The methoxy (-OCH3) substituent adds an extra layer of complexity and influences the compound's interaction with biological systems.
This compound is notable not just for its intricate structure but also for the potential applications in the pharmaceutical industry. As an indole derivative, it may exhibit interesting pharmacological properties.
Applications in Research:
- Pharmacology: Researchers investigate compounds like this for their potential therapeutic effects, particularly in targeting specific diseases.
- Biochemical Studies: Its unique structure allows for exploration of enzyme interactions and receptor binding.
In the words of one esteemed chemist, "The beauty of organic compounds lies in their ability to connect intricately with biological systems." This highlights the continual intrigue for scientists exploring the depths of organic chemistry and how structures relate to function. As research advances, this compound may unlock new pathways in drug discovery and development.
Synonyms
indomethacin
53-86-1
indometacin
Indocin
Indomethacine
Indometacine
Indocid
Reumacide
Indomethazine
Metindol
Artrinovo
Confortid
Idomethine
Indomecol
Indomethacinum
Metartril
Methazine
Artrivia
Dolovin
Imbrilon
Indacin
Indomed
Indomee
Indoptol
Infrocin
Metacen
Sadoreum
Amuno
Inacid
Tannex
Indo-rectolmin
Inteban sp
Artracin
Durametacin
Indoptic
Inflazon
Mikametan
Lausit
Mezolin
Mobilan
Indo-tablinen
Indo-Lemmon
Indometacinum
Indometacina
Indometacyna
Indometicina
Indocin Sr
Aconip
2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-
Indmethacine
Dolcidium
Elmetacin
Indomethine
Indorektal
Tivorbex
Catlep
Indoxen
Vonum
Indo-phlogont
Chibro-amuno
Bonidon Gel
Dolcidium PL
Rheumacin LA
Osmosin
1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
CCRIS 3502
HSDB 3101
Indometacine [INN-French]
Indometacinum [INN-Latin]
Indometacina [INN-Spanish]
FLAM
MFCD00057095
Inteban
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
NCI-C56144
UNII-XXE1CET956
EINECS 200-186-5
XXE1CET956
Indometacin [INN]
NSC-757061
1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
BRN 0497341
USAN
Indomethacin (Indocid, Indocin)
CHEBI:49662
CHEMBL6
NSC-77541
IMN
Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-
Indomethacin [USAN:USP]
alpha-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1h-indol-3-yl}acetic acid
N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid
MLS000069402
DTXSID9020740
(1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-yl)acetic acid
1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid
1-(p-Chlorobenzoyl)-2-methoxy-3-methyl-1H-indole-3-acetic Acid
Indomet 140
EC 200-186-5
[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
5-22-05-00239 (Beilstein Handbook Reference)
{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
NSC 757061
CAS-53-86-1
1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico
NCGC00015562-18
Indomethancin
1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
Arthrexin
Bonidin
Bonidon
Indameth
Indomod
Miametan
SMR000058195
Indomo
Flexin continus
Hicin
Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy
Chrono-indicid
Chrono-indocid
Indometacyna [Polish]
Indometicina [Spanish]
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Indo-Spray
Indomethacin (USAN:USP)
Indolar SR
Indometacine (INN-French)
Indometacinum (INN-Latin)
Indometacina (INN-Spanish)
INDOMETACIN (MART.)
INDOMETACIN [MART.]
DTXCID50740
INDOMETHACIN (USP-RS)
INDOMETHACIN [USP-RS]
1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indoleacetic acid
INDOMETACIN (EP MONOGRAPH)
INDOMETACIN [EP MONOGRAPH]
INDOMETHACIN (USP MONOGRAPH)
INDOMETHACIN [USP MONOGRAPH]
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid
(1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETIC ACID
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetic acid
Indocin-SR
Indochron E-R
Indocin (TN)
ACEMETACIN IMPURITY B (EP IMPURITY)
ACEMETACIN IMPURITY B [EP IMPURITY]
Aconip (TN)
Indomethacin (USP)
NSC77541
Indocid (pharmaceutical)
SR-01000000014
Indomethacin & MAP-30
Indocollyre
Indonol
Innamit
1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-Indole-3-acetic acid
IndomethacinER
Indomethacin ER
2-{1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methylindol-3-yl}acetic acid
4kyk
(1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
Indomethacin,(S)
Prestwick_597
Indomethacin (GMP)
INDREN
Indometacinum (Latin)
Opera_ID_56
Spectrum_000919
Tocris-1708
1z9h
Indomethacin (Standard)
1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure [German]
1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico [Spanish]
Prestwick0_000272
Prestwick1_000272
Prestwick2_000272
Prestwick3_000272
Spectrum2_000970
Spectrum3_000468
Spectrum4_000018
Spectrum5_000868
INDOMETACIN [JAN]
INDOMETHACIN [MI]
Lopac-I-7378
Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy [Polish]
Indometacin (Indomethacin)
CHRONO-INDOCID 75
MolMap_000032
UPCMLD-DP023
I 7378
Indometacin (JP18/INN)
INDOMETHACIN [HSDB]
INDOMETHACIN [USAN]
SCHEMBL9300
INDOMETHACIN [VANDF]
Indomethacin Extended-release
Lopac0_000692
Oprea1_686105
BSPBio_000144
BSPBio_001149
BSPBio_002176
INDOMETACIN [WHO-DD]
INDOMETACIN [WHO-IP]
Indomethacine impurity mixture
KBioGR_000395
KBioGR_000489
KBioSS_000489
KBioSS_001399
MLS001074194
MLS006011845
BIDD:GT0132
DivK1c_000271
SPECTRUM1500350
SPBio_000979
SPBio_002363
BPBio1_000160
GTPL1909
Indomethacin, >=99% (TLC)
UPCMLD-DP023:001
BDBM17638
CGIGDMFJXJATDK-UHFFFAOYSA-
HMS500N13
KBio1_000271
KBio2_000489
KBio2_001399
KBio2_003057
KBio2_003967
KBio2_005625
KBio2_006535
KBio3_000897
KBio3_000898
KBio3_001396
1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure
C01EB03
M01AB01
M02AA23
S01BC01
Indomethacin - CAS 53-86-1
NINDS_000271
Bio2_000405
Bio2_000885
HMS1362I11
HMS1568H06
HMS1792I11
HMS1920F21
HMS1990I11
HMS2089N19
HMS2091N09
HMS2095H06
HMS2231J10
HMS3262K05
HMS3268A14
HMS3374F07
HMS3403I11
HMS3414N13
HMS3430L03
HMS3649K17
HMS3655O04
HMS3678N11
HMS3712H06
HMS3747K21
HMS3884E08
Indomethacin - Bio-X trade mark
INDOMETHACIN [ORANGE BOOK]
Indomethacin-d4(chlorobenzoyl-d4)
Pharmakon1600-01500350
BCP18951
MDA37708
Tox21_113109
Tox21_201791
Tox21_300266
Tox21_500692
AC-532
CCG-40186
HB4422
HY-14397G
HY-14397R
INDOMETACINUM [WHO-IP LATIN]
NSC757061
s1723
STL257874
AKOS000592893
Tox21_113109_1
AT13679
DB00328
FI24585
Indometacin 1.0 mg/ml in Acetonitrile
KS-5255
LP00692
SDCCGSBI-0050670.P005
IDI1_000271
IDI1_002160
NCGC00015562-01
NCGC00015562-02
NCGC00015562-03
NCGC00015562-04
NCGC00015562-05
NCGC00015562-06
NCGC00015562-07
NCGC00015562-08
NCGC00015562-09
NCGC00015562-10
NCGC00015562-11
NCGC00015562-12
NCGC00015562-13
NCGC00015562-14
NCGC00015562-15
NCGC00015562-16
NCGC00015562-17
NCGC00015562-19
NCGC00015562-20
NCGC00015562-21
NCGC00015562-22
NCGC00015562-24
NCGC00015562-25
NCGC00015562-40
NCGC00024135-02
NCGC00024135-04
NCGC00024135-05
NCGC00024135-06
NCGC00024135-07
NCGC00024135-08
NCGC00024135-09
NCGC00024135-10
NCGC00024135-11
NCGC00024135-12
NCGC00024135-13
NCGC00024135-14
NCGC00024135-15
NCGC00254075-01
NCGC00259340-01
NCGC00261377-01
BI166166
BP-30207
HY-14397
NCI60_041708
O-Desmethyl-des-4-chlorobenzoylacemetacin
SBI-0050670.P004
DB-052413
AB00052022
EU-0100692
I0655
NS00000217
SW196768-5
EN300-16807
Indomethacin, meets USP testing specifications
BIM-0050670.0001
C01926
D00141
S00108
AB00052022-20
AB00052022-21
AB00052022_23
AB00052022_24
L000959
Q409231
SR-01000000014-2
SR-01000000014-4
SR-01000000014-6
1-(4-Chlorobenzoyl)-5-methoxy-2-met hyl-1H-indole
BRD-K57222227-001-06-1
BRD-K57222227-001-18-6
BRD-K57222227-001-27-7
BRD-K57222227-001-28-5
BRD-K57222227-001-29-3
BRD-K57222227-001-30-1
SR-01000000014-10
SR-01000000014-16
Z56784896
1-p-chlorobenzoyl-2-methyl-5-methoxyindol-3-acetic acid
1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-acetic acid
1-(p-chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid
1-(4-chloro-benzoyl)-5-methoxy-2-methyl-3-indolyl-acetic acid
1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indole-acetic acid
1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acid
Indomethacin, European Pharmacopoeia (EP) Reference Standard
N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1-H-indole-3-acetic acid
Indomethacin, United States Pharmacopeia (USP) Reference Standard
N-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID
.alpha.-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid
[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid #
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid & MAP-30
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid;Indometacin
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl- (9CI)
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2 methylindol-3-yl}acetic acid
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2methylindol-3-yl}acetic acid
Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- (8CI)
Indomethacin, Pharmaceutical Secondary Standard; Certified Reference Material
200-186-5
InChI=1/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
Solubility of 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid
The solubility of the compound 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid, with the chemical formula C19H16ClNO4, can be influenced by various factors, including its molecular structure and the presence of polar and non-polar functional groups.
Factors Affecting Solubility:
In practical terms, this compound is likely to exhibit moderate solubility in organic solvents due to its complex structure. However, its solubility in water may be limited due to the bulkiness of the aromatic rings and the chlorobenzoyl moiety. It is important to note that, as a rule of thumb, compounds with a higher degree of aromatic character typically show lower solubility in aqueous environments.
Overall, the solubility of 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid can be characterized as variable and dependent on the solvent system employed, highlighting the need for empirical testing to determine precise solubility values.