Skip to main content

Ketamine

ADVERTISEMENT
Identification
Molecular formula
C13H16ClNO
CAS number
6740-88-1
IUPAC name
2-[1-(4-chlorophenyl)cyclohexoxy]-N,N-diethyl-ethanamine
State
State
Ketamine is generally handled as a solid when in powder form, and as a colorless liquid when used in medical treatments. In both forms, it is typically highly soluble in water.
Melting point (Celsius)
258.00
Melting point (Kelvin)
531.20
Boiling point (Celsius)
237.70
Boiling point (Kelvin)
510.90
General information
Molecular weight
237.73g/mol
Molar mass
237.7250g/mol
Density
1.0810g/cm3
Appearence

Ketamine typically appears as a white crystalline powder, though it is also available in liquid form for medical use. The crystalline powder can sometimes be compacted into solid crystals or pellets for distribution. The liquid form is generally a clear solution.

Comment on solubility

Solubility of 2-[1-(4-chlorophenyl)cyclohexoxy]-N,N-diethyl-ethanamine

The solubility of 2-[1-(4-chlorophenyl)cyclohexoxy]-N,N-diethyl-ethanamine, with the chemical formula C13H16ClNO, is influenced by various factors that reflect its chemical structure and properties. Generally, **solubility** can be categorized based on a few key aspects:

  • Polarity: The compound contains a chlorophenyl group and a cyclohexoxy structure, which may suggest a degree of non-polar character. This non-polar nature usually indicates that it may have limited solubility in polar solvents like water.
  • Hydrogen Bonding: The presence of the nitrogen atom in the amine group enables the potential for hydrogen bonding, which can enhance solubility in polar protic solvents such as alcohols.
  • Molecular Volume: The relatively large molecular structure can also impede solubility in common solvents due to steric hindrance, making it less likely to dissolve readily in aqueous solutions.

In summary, while 2-[1-(4-chlorophenyl)cyclohexoxy]-N,N-diethyl-ethanamine may exhibit some solubility characteristics, it is likely to be more soluble in **organic solvents** rather than in polar solvents. This aligns with the general principle that “like dissolves like,” where compounds of similar polarity tend to dissolve better together. Thus, the compound is expected to show limited solubility in water but could fare better in non-polar or semi-polar organic solvents.

Interesting facts

Interesting Facts about 2-[1-(4-chlorophenyl)cyclohexoxy]-N,N-diethyl-ethanamine

This compound, known for its complex structure, falls under the category of organic compounds and showcases a fascinating blend of chemistry and pharmacology. Here are some intriguing aspects of this molecule:

  • Pharmacological Interest: Compounds like this one may exhibit potential therapeutic effects, making them subjects of interest in medicinal chemistry. Their structural components can interact with various biological pathways, which may lead to the development of new drugs.
  • Structural Diversity: The presence of a cyclohexyl group along with a chlorophenyl moiety introduces significant stereochemical complexity. This diversity can influence the compound's binding affinity to biological targets.
  • Chlorine Atom Influence: The presence of the chlorine atom is noteworthy. Halogens often enhance the lipophilicity of organic molecules, which can affect their absorption and distribution within biological systems.
  • Synthesis Challenges: The synthesis of such compounds often requires advanced techniques in organic chemistry, including specific reaction conditions and catalysts, which challenges students and researchers alike.
  • Research Applications: Compounds of this nature are often utilized in drug design and can be studied to understand the mechanism of action of similar substances, paving the way for innovations in healthcare.

In the context of studying organic chemistry, understanding such compounds provides invaluable insights into molecular interactions and drug development. As René Dubos once said, “Since the dawn of civilization, scientists have been at the service of mankind.” Compounds like this reflect the ongoing quest for knowledge and the potential for future medical breakthroughs.


This compound’s intricate design not only holds promise for scientists exploring its properties but also serves as an excellent example of the breadth of organic chemistry.

Synonyms
Clofenciclan
5632-52-0
Chlorphencyclan
Clofencician
Clofenciclane
Veritan
Clofenciclan [INN]
Clofenciclano
Clofenciclanum
Clofenciclane [INN-French]
Clofenciclanum [INN-Latin]
Clofenciclano [INN-Spanish]
CHLORPHENECYCLANE
KSW 786
UNII-P4BVX0D2MX
P4BVX0D2MX
BRN 2335382
SC 12333
2-(1-(p-Chlorophenyl)cyclohexyl)triethylamine
2-((1-(p-Chlorophenyl)cyclohexyl)oxy)triethylamine
CLOFENCICLAN [WHO-DD]
DTXSID60204865
Diethyl-(2-(1-(4-chlorphenyl)cyclohexyloxy)ethyl)amin
Triethylamine, 2-((1-(p-chlorophenyl)cyclohexyl)oxy)-
Ethanamine, 2-((1-(4-chlorophenyl)cyclohexyl)oxy)-N,N-diethyl-
Clofenciclane (INN-French)
Clofenciclanum (INN-Latin)
Clofenciclano (INN-Spanish)
DTXCID90127356
Ethanamine, 2-((1-(4-chlorophenyl)cyclohexyl)oxy)-N,N-diethyl-(9CI)
2-[1-(4-chlorophenyl)cyclohexyl]oxy-N,N-diethylethanamine
SCHEMBL729407
CHEMBL2106084
EN300-18567845
Q1102163
(2-{[1-(4-chlorophenyl)cyclohexyl]oxy}ethyl)diethylamine
2-{[1-(4-chlorophenyl)cyclohexyl]oxy}-N,N-diethylethanamine