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Memantine

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Identification
Molecular formula
C12H21NO
CAS number
19982-08-2
IUPAC name
2-(1-adamantyl)-N-ethyl-ethanamine
State
State

At room temperature, memantine is in a solid-state, usually existing in crystalline powder form.

Melting point (Celsius)
292.80
Melting point (Kelvin)
566.00
Boiling point (Celsius)
332.30
Boiling point (Kelvin)
605.50
General information
Molecular weight
215.35g/mol
Molar mass
215.3530g/mol
Density
1.2000g/cm3
Appearence

Memantine appears as a white to off-white powder. It is generally crystalline in nature and has no distinct odor. The compound is stable under normal ambient temperatures and storage conditions. It is soluble in water and various solvents, depending on the pH and temperature.

Comment on solubility

Solubility of 2-(1-adamantyl)-N-ethyl-ethanamine

The solubility of 2-(1-adamantyl)-N-ethyl-ethanamine, often referred to as a substituted amine, exhibits some interesting properties due to its unique structure. Here are a few key points to consider:

  • Polarity: The presence of both hydrophobic adamantyl and hydrophilic ethyl groups can lead to varied solubility in different solvents.
  • Solvent Compatibility: It is typically more soluble in non-polar solvents such as chloroform or ethyl acetate compared to polar solvents like water.
  • Hydrogen Bonding: The amine functional group can engage in hydrogen bonding, although the bulky adamantyl group hinders such interactions, affecting overall solubility.
  • Temperature Dependence: Solubility can increase with temperature, which is a common characteristic for many organic compounds.

In summary, while 2-(1-adamantyl)-N-ethyl-ethanamine shows limited solubility in water, its structure allows for notable solubility in organic solvents. This dual nature highlights the compound's utility in various chemical applications, where solvent choice can be crucial.

Interesting facts

Interesting Facts about 2-(1-adamantyl)-N-ethyl-ethanamine

2-(1-adamantyl)-N-ethyl-ethanamine is an intriguing chemical compound, largely recognized for its unique structural features and potential applications in various fields. Here's what makes it interesting:

  • Unique Structure: This compound features an adamantane group, known for its distinctive cage-like structure and remarkable stability. The incorporation of such a feature often enhances the compound's performance in various chemical reactions.
  • Biological Significance: Compounds like this one have been explored for their interactions with biological systems. They may exhibit potential pharmacological activities, which lead researchers to investigate their effects on neurotransmitter systems.
  • Versatile Applications: The structural modifications in its class allow for a wide range of applications. It can be utilized in the development of pharmaceuticals or as a ligand in biochemical assays due to its unique molecular characteristics.
  • Research Potential: The synthetic pathways to produce such compounds are areas of active research. Understanding the reactivity and stability of 2-(1-adamantyl)-N-ethyl-ethanamine could pave the way for the development of new agents in medicinal chemistry.
  • Relative Stability: The adamantyl moiety is often associated with increased metabolic stability. This property is particularly beneficial when designing compounds intended for therapeutic use, as increased stability often correlates with longer-lasting effects in biological systems.

To summarize, 2-(1-adamantyl)-N-ethyl-ethanamine is not only a member of a fascinating class of compounds but also a source of considerable academic interest. As research continues, the full potential of such compounds remains to be uncovered.

Synonyms
N-[2-(1-adamantyl)ethyl]-N-ethylamine
27666-70-2
[2-(adamantan-1-yl)ethyl](ethyl)amine
2-(Adamantan-1-yl)-N-ethylethan-1-amine
MFCD09035538
2-(1-adamantyl)-N-ethylethanamine
2-(1-adamantyl)-N-ethyl-ethanamine
F1988-0005
SCHEMBL27567153
SMSSF-0044131
ALBB-007396
STK504514
AKOS000266024
2-(1-adamantanyl)-1-(ethylamino)ethane
CS-0298699
EN300-242096
H24585
N-ethyl-2-(tricyclo[3.3.1.1~3,7~]dec-1-yl)ethanamine