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Etodolac

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Identification
Molecular formula
C17H17NO3
CAS number
41340-25-4
IUPAC name
2-(1-benzoyl-2-methyl-indol-3-yl)acetic acid
State
State

Etodolac is typically a solid at room temperature.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.20
Boiling point (Celsius)
474.90
Boiling point (Kelvin)
748.00
General information
Molecular weight
287.33g/mol
Molar mass
287.3470g/mol
Density
1.3660g/cm3
Appearence

Etodolac appears as a white or almost white crystalline powder. It is slightly soluble in alcohol and very slightly soluble in water.

Comment on solubility

Solubility of 2-(1-benzoyl-2-methyl-indol-3-yl)acetic acid

The solubility of 2-(1-benzoyl-2-methyl-indol-3-yl)acetic acid can be influenced by various factors, making its behavior in different solvents quite intriguing. Generally, this compound is expected to exhibit moderate solubility due to its complex aromatic structure. Here are some insights into its solubility characteristics:

  • Polarity: The presence of both polar (carboxylic acid) and non-polar (aromatic) functional groups indicates that solubility might vary significantly between polar and non-polar solvents.
  • Common Solvents: It may show reasonable solubility in solvents such as ethanol or methanol due to hydrogen bonding capabilities, while being less soluble in non-polar organic solvents like hexane.
  • Temperature Dependence: Solubility is likely to increase with rising temperatures, a common characteristic for many organic compounds.

In general, the solubility of organic compounds can often be summarized by the phrase, "like dissolves like." Thus, the dual nature of this compound could provide distinct solubility patterns depending on the solvent used. Understanding and exploring these solubility behaviors is vital for applications in fields such as pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 2-(1-benzoyl-2-methyl-indol-3-yl)acetic acid

2-(1-benzoyl-2-methyl-indol-3-yl)acetic acid is a fascinating organic compound that bridges the fields of chemistry and medicinal research. Here are some intriguing aspects about this compound:

  • Significance in Pharmacology: This compound has garnered interest in pharmacological studies due to its potential therapeutic properties. Its structure resembles other biologically active molecules, suggesting it could play a role in drug development.
  • Indole Derivative: The presence of the indole ring, a common feature in many natural products and pharmaceuticals, indicates that this compound may exhibit interesting biological activities. Indoles are known for their role in a variety of biological processes.
  • Synthetic Versatility: The synthetic route towards producing this compound can involve various organic reactions, showcasing the rich tapestry of organic synthesis techniques. This opens pathways for chemists to explore diverse methodologies in compound formation.
  • Research Applications: Compounds like this are vital in research for studying enzymatic activity, signaling pathways, and even as potential anti-cancer agents, contributing to our understanding of complex biological mechanisms.
  • Intriguing Chemical Behavior: The carboxylic acid functional group in this compound suggests it may participate in various chemical reactions, such as esterification and amidation, making it a valuable building block for more complex structures.

In summary, 2-(1-benzoyl-2-methyl-indol-3-yl)acetic acid is not just a chemical entity but a molecule of interest with profound implications in medicinal chemistry and organic synthesis. Its presence in the realm of drug discovery exemplifies how intricate and vital organic compounds can be in advancing scientific knowledge and developing new therapies.

Synonyms
Delmetacin
16401-80-2
Delmetacina
Delmetacine
Delmetacinum
UR-2310
1-Benzoyl-2-methylindole-3-acetic acid
I9Q51XHI1K
DTXSID90167696
delmethacin
DTXCID9090187
Delmetacin [INN]
Demetacin
Demethacin
2-(1-benzoyl-2-methylindol-3-yl)acetic acid
1H-Indole-3-aceticacid, 1-benzoyl-2-methyl-
Delmetacin; Demetacin
2-(1-Benzoyl-2-methyl-1H-indol-3-yl)acetic acid
Delmetacina [Spanish]
Delmetacine [INN-French]
Delmetacinum [INN-Latin]
Delmetacina [INN-Spanish]
UNII-I9Q51XHI1K
UR 2310
BRN 0488508
1-Benzoyl-2-methyl-3-indolylessigsaeure
1H-Indole-3-acetic acid, 1-benzoyl-2-methyl-
2-[1-(Benzoyl)-2-methylindol-3-yl]acetic acid
5-22-03-00124 (Beilstein Handbook Reference)
SCHEMBL286727
INDOLE-3-ACETIC ACID, 1-BENZOYL-2-METHYL-
orb1819183
CHEMBL2104243
1-benzoyl-2-methyl-3-indoleacetic acid
DA-29807
TS-09498
HY-106473
CS-0025883
NS00120297
Q27280616