Interesting facts
Interesting Facts about 2-[(1-benzyl-4-piperidyl)methyl]-5,6-dimethoxy-indan-1-one; hydrochloride
This compound is a fascinating example of a synthetic organic molecule, notable for its unique structural characteristics and potential pharmaceutical applications. Here are some engaging insights into this compound:
- Complex Structure: The compound features an indanone core integrated with dimethoxy groups and a piperidine moiety, showcasing a rich variety of functional groups, which often contribute to enhanced biological activity.
- Pharmacological Potential: Due to the piperidine derivative in its structure, this compound may exhibit interesting interactions with neurotransmitter receptors. Compounds like this are often studied for potential antidepressant or anxiolytic properties.
- Diverse Research Applications: Compounds related to indanones have been explored not just in medicinal chemistry but also in materials science and organic electronics, due to their intriguing electronic properties.
- Synthetic Interest: The multi-step synthesis of this compound provides an excellent platform for chemistry students to learn about various organic reactions, including alkylation, acylation, and the manipulation of nitrogen-containing functionalities.
- Historical Context: Compounds like these trace their roots back to the discovery of various psychotropic agents, marking a significant chapter in medicinal chemistry's evolution to address mental health issues in society.
In summary, 2-[(1-benzyl-4-piperidyl)methyl]-5,6-dimethoxy-indan-1-one; hydrochloride stands as an exciting compound that intertwines with the realms of medicinal chemistry, organic synthesis, and therapeutic exploration. Its ongoing study exemplifies the continuous quest for innovative solutions in healthcare.
Synonyms
Donepezil hydrochloride
120011-70-3
Donepezil HCl
Aricept
110119-84-1
BNAG
2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride
Aricept ODT
E-2020
E2020
E 2020
E 2020 (pharmaceutical)
ADLARITY
Donepezil (Hydrochloride)
Donepezil, HCl
2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride
UNII-3O2T2PJ89D
NSC-737535
NSC-758882
3O2T2PJ89D
1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1)
DTXSID0046698
CHEMBL1678
CHEBI:4696
DTXCID8026698
1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl
Donepezil hydrochloride [USAN:USP]
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride
120011-70-3 (HCl)
(+-)-2-((1-Benzyl-4-piperidyl)methyl)-5,6-dimethoxy-1-indanone hydrochloride
E2020;E-2020
NAMZARIC COMPONENT DONEPEZIL HYDROCHLORIDE
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride
1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-, hydrochloride
Eranz
Donepezil hydrochloride (USAN:USP)
2-(1-Benzyl-4-piperidylmethyl)-5,6-dimethoxy-1-indanone Hydrochloride
2-(1-Benzyl-piperidin-4-ylmethyl)-5,6-dimethoxy-indan-1-one hydrochloride
DONEPEZIL HYDROCHLORIDE (MART.)
DONEPEZIL HYDROCHLORIDE [MART.]
DONEPEZIL HYDROCHLORIDE (USP-RS)
DONEPEZIL HYDROCHLORIDE [USP-RS]
SMR000449292
CAS-120011-70-3
Donepezil hydrochloride [USAN]
DONEPEZIL HYDROCHLORIDE (EP MONOGRAPH)
DONEPEZIL HYDROCHLORIDE [EP MONOGRAPH]
DONEPEZIL HYDROCHLORIDE (USP MONOGRAPH)
DONEPEZIL HYDROCHLORIDE [USP MONOGRAPH]
NSC 737535
NSC 758882
NCGC00167537-01
C24H29NO3.HCl
Memorit
Memac
Aricept Evess
AriceptODT
Donepezil,HCl
Aricept D
1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride
Donepezil Hydrochloride; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (9CI); Aricept; Aricept D; BNAG; E 2020
Aricept (TN)
MFCD00881312
Donepezil hydrochloride?
Donepezil Hyrochloride5mg
Donepezil HCl (Aricept)
Donepezil Hydrochloride10mg
Donepezil Hydrochloride5 mg
SCHEMBL1815
Donepezil hydrochloride,(S)
MLS000758276
MLS001401387
donepezil hydrochloride hydrate
HY-B0034R
XWAIAVWHZJNZQQ-UHFFFAOYSA-N
Pharmakon1600-01504403
Donepezil HCl - Bio-X trade mark
BCP02205
BCP24884
HY-B0034
DONEPEZIL HYDROCHLORIDE [MI]
Tox21_112534
AC-913
Donepezil hydrochloride (JP18/USP)
DONEPEZIL HYDROCHLORIDE [JAN]
HB2083
NSC737535
NSC758882
s2462
Donepezil (Hydrochloride) (Standard)
1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride
AKOS000277343
AKOS016340656
Tox21_112534_1
CCG-101043
CCG-213309
CS-0863
DONEPEZIL HYDROCHLORIDE [VANDF]
KS-1051
NC00293
DONEPEZIL HYDROCHLORIDE [WHO-DD]
NCGC00167537-02
BD164380
D4099
DONEPEZIL HYDROCHLORIDE [ORANGE BOOK]
D00670
E-2022
EN300-269733
DONEPEZIL HYDROCHLORIDE COMPONENT OF NAMZARIC
Donepezil hydrochloride monohydrate, >=98% (HPLC)
Q27106438
884740-09-4 (.H2O)
Donepezil Hydrochloride 1.0 mg/ml in Methanol (as free base)
(+/-)-2-((1-BENZYL-4-PIPERIDYL)METHYL)-5,6-DIMETHOXY-1-INDANONE HYDROCHLORIDE
2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]-1H-inden-1-one
rac-2-((1-benzylpiperidin-4-yl)methyl)-5,6-dimethoxyindan-1-one hydrochloride
(+-)-2,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride
(2RS)-2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one monohydrochloride
rac-1-benzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidinium chloride
Solubility of 2-[(1-benzyl-4-piperidyl)methyl]-5,6-dimethoxy-indan-1-one; hydrochloride
The solubility of 2-[(1-benzyl-4-piperidyl)methyl]-5,6-dimethoxy-indan-1-one; hydrochloride (C28H34ClNO3) is an important factor to consider in various applications. This compound demonstrates varying solubility characteristics that can significantly influence its pharmacological efficacy and formulation processes.
Key Aspects of Solubility:
In summary, understanding the solubility of 2-[(1-benzyl-4-piperidyl)methyl]-5,6-dimethoxy-indan-1-one; hydrochloride is crucial for optimizing its use in biochemical applications. The factors influencing solubility, such as solvent choice, pH, and temperature, must be taken into account to achieve desired concentrations and maximize therapeutic efficacy.