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Tropicamide

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Identification
Molecular formula
C17H23NO3
CAS number
1508-75-4
IUPAC name
2-(1-ethylpyrrolidin-2-yl)ethyl 2-methoxy-2,2-diphenyl-acetate
State
State

At room temperature, Tropicamide is typically found in a solid state as a white crystalline powder. When prepared as an ophthalmic solution, it is a liquid.

Melting point (Celsius)
32.00
Melting point (Kelvin)
305.15
Boiling point (Celsius)
345.50
Boiling point (Kelvin)
618.65
General information
Molecular weight
358.47g/mol
Molar mass
358.4660g/mol
Density
1.1454g/cm3
Appearence

Tropicamide typically appears as a white crystalline powder when pure. It is commonly used in the pharmaceutical industry and, as such, is often formulated into an ophthalmic solution where it appears as a clear, colorless liquid.

Comment on solubility

Solubility of 2-(1-ethylpyrrolidin-2-yl)ethyl 2-methoxy-2,2-diphenyl-acetate

The solubility of 2-(1-ethylpyrrolidin-2-yl)ethyl 2-methoxy-2,2-diphenyl-acetate in various solvents can be quite intriguing, as it showcases the influence of molecular structure on solubility properties. This compound is known for exhibiting moderate solubility in organic solvents while behaving differently in polar environments.

Solvent Preferences:

In terms of solubility, the following characteristics are noteworthy:

  • Polar Solvents: Generally, this compound shows lower solubility in polar solvents like water due to its bulky and hydrophobic diphenyl groups.
  • Non-Polar Solvents: It exhibits better solubility in non-polar organic solvents such as dichloromethane or ethyl acetate, thanks to the hydrophobic interactions brought about by the diphenyl moieties.
  • Moderate Organic Solvents: Solubility in solvents like ethanol or methanol can vary but is often categorized as moderate, attributable to the presence of the methoxy group which can create some favorable interactions.

Interestingly, the interactions in solution are highly linked to the compound's functional groups and steric hindrance, which can impact effective solvation. Hence, the selection of an appropriate solvent for dissolution often relies on a careful consideration of both the diphenyl substituents and the alkyl chain present in the structure.

Overall, understanding the solubility profile of this compound not only aids in practical applications but also provides insight into the subtle complexities of solute-solvent interactions.

Interesting facts

Interesting Facts about 2-(1-ethylpyrrolidin-2-yl)ethyl 2-methoxy-2,2-diphenyl-acetate

The compound 2-(1-ethylpyrrolidin-2-yl)ethyl 2-methoxy-2,2-diphenyl-acetate is a fascinating molecule with significant implications in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Structural Complexity: This compound features a unique blend of functional groups, particularly a diphenylacetate core combined with a pyrrolidine ring. This structural diversity is often associated with enhanced biological activity.
  • Potential Therapeutic Applications: Compounds with similar structures have been explored for their potential use in treating various conditions, including neurological disorders and as analgesics. The ethylpyrrolidine moiety may influence neurotransmitter activity, making it a candidate for further research.
  • Importance of Side Chains: The addition of the methoxy group can significantly affect the compound’s reactivity and solubility, highlighting the importance of side chains in drug design. Modifications to these groups can lead to variations in pharmacological profiles.
  • Research and Development: This compound represents a class of ligands that could play a role in receptor interactions. Investigations into how these ligands bind to specific targets in the body can pave the way for novel therapeutic agents.
  • Spacial Configuration: The 3D arrangement of the atoms in this molecule can greatly affect its biological function. Understanding and analyzing these configurations can lead scientists to optimize compounds for better efficacy.

In summary, 2-(1-ethylpyrrolidin-2-yl)ethyl 2-methoxy-2,2-diphenyl-acetate showcases the intricate relationship between chemical structure and biological function. Its potential applications in pharmacology and the ongoing research into its characteristics reflect the ever-evolving nature of medicinal chemistry.