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Tranexamic Acid

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Identification
Molecular formula
C8H15NO2
CAS number
1197-18-8
IUPAC name
2-[1-(hydroxymethyl)cyclohexyl]acetic acid
State
State

At room temperature, Tranexamic Acid is typically a stable solid.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
349.57
Boiling point (Kelvin)
622.72
General information
Molecular weight
157.21g/mol
Molar mass
157.2110g/mol
Density
1.4340g/cm3
Appearence

Tranexamic Acid appears as a white crystalline powder. It is stable under standard conditions and has poor solubility in water but is slightly soluble in acetone and ethanol.

Comment on solubility

Solubility of 2-[1-(hydroxymethyl)cyclohexyl]acetic acid

2-[1-(hydroxymethyl)cyclohexyl]acetic acid, with its unique structure, exhibits interesting solubility characteristics which can be influenced by several key factors:

  • Polarity: The presence of the hydroxymethyl group contributes to the molecule's polarity, enhancing its ability to dissolve in polar solvents such as water.
  • Hydrogen Bonding: This compound is capable of forming hydrogen bonds due to both the carboxylic acid and hydroxymethyl functional groups. As a result, it may exhibit higher solubility in polar solvents compared to non-polar solvents.
  • pH Dependence: The solubility can be affected by the pH of the solution. In acidic or neutral conditions, the carboxylic acid group remains protonated, while in basic conditions, it can deprotonate, thus affecting solubility dynamics.
  • Temperature Effects: Increasing temperature can enhance solubility for many organic compounds, including this one, as it may promote dissolution by increasing molecular motion.

In general, 2-[1-(hydroxymethyl)cyclohexyl]acetic acid demonstrates decent solubility in water and various organic solvents, making it relatively versatile for applications in different chemical environments.

Interesting facts

Exploring 2-[1-(hydroxymethyl)cyclohexyl]acetic acid

2-[1-(hydroxymethyl)cyclohexyl]acetic acid, a fascinating organic compound, is attracting attention in various fields due to its unique structure and potential applications. Known for its role as a building block in medicinal chemistry, this compound exhibits several interesting characteristics:

  • Structural Uniqueness: The compound features a cyclohexyl group, which introduces rigidity to its molecular structure while providing numerous sites for potential interactions with biological targets.
  • Biological Activity: Compounds similar to 2-[1-(hydroxymethyl)cyclohexyl]acetic acid have been investigated for their pharmacological properties, including anti-inflammatory and analgesic effects. This opens up avenues for research in drug development.
  • Hydroxymethyl Functionality: The presence of the hydroxymethyl group enhances the polarity of the molecule, which can affect solubility and reactivity, making it more amenable to various chemical transformations.
  • Role in Synthesis: As an important intermediate in organic synthesis, this compound can be used to synthesize more complex molecules, demonstrating the significance of understanding its chemical behavior.
  • Environmental Impact: Research has suggested that compounds with similar structural features may interact with biological systems, making it crucial to analyze their environmental fate and potential ecological effects.

In conclusion, 2-[1-(hydroxymethyl)cyclohexyl]acetic acid embodies a blend of structure and potential, paving the way for innovations in both synthetic chemistry and pharmacology. As chemists continue to explore this compound and its derivatives, they uncover the intricate ways organic compounds can contribute to the advancement of science and technology.

Synonyms
Hexacyclonic acid
7491-42-1
Hexacyclonate
2-[1-(hydroxymethyl)cyclohexyl]acetic acid
Cyclohexaneacetic acid, 1-(hydroxymethyl)-
2K0FP9UB6A
Hexacyclonsaeure
Acidum hexacyclonicum
2-(1-(Hydroxymethyl)cyclohexyl)acetic acid
UNII-2K0FP9UB6A
1-(Hydroxymethyl)cyclohexylessigsaeure
1-(Hydroxymethyl)cyclohexaneacetic acid
SCHEMBL727930
CHEMBL2110826
DTXSID30225885
CHEBI:167168
[1-(hydroxymethyl)cyclohexyl]acetic acid
1-(hydroxymethyl)-cyclohexaneacetic acid
3,3-pentamethylene-4-hydoxybutyric acid
1-(HYDROXYMETHYL)CYCLOHEXANEACETATE
1-(hydroxymethyl)cyclohexane-1-acetic acid
EN300-2010624
Q15409435