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Methamphetamine Nitrile

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Identification
Molecular formula
C17H18N2
CAS number
7527-07-9
IUPAC name
2-[(1-methyl-2-phenyl-ethyl)amino]-2-phenyl-acetonitrile
State
State

At room temperature, it is a solid.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
236.33g/mol
Molar mass
236.3260g/mol
Density
1.0580g/cm3
Appearence

The compound appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[(1-methyl-2-phenyl-ethyl)amino]-2-phenyl-acetonitrile

The solubility of 2-[(1-methyl-2-phenyl-ethyl)amino]-2-phenyl-acetonitrile can be influenced by several factors including temperature, pH, and the presence of other solvents. 

Factors Influencing Solubility

  • Temperature: Generally, the solubility of organic compounds increases with temperature, which may enhance the dissolution of this acetonitrile derivative.
  • Polarity: The presence of an amino group in the structure suggests that it may exhibit greater solubility in polar solvents compared to non-polar ones.
  • pH Levels: Since it contains an amino functional group, a change in pH can protonate the amine, potentially increasing solubility in acidic environments.

Overall, it is essential to note that the solubility of 2-[(1-methyl-2-phenyl-ethyl)amino]-2-phenyl-acetonitrile in various solvents is specific to the conditions applied. As a general rule, solubility can significantly vary between different media due to structural characteristics and environmental factors. Further studies may be necessary to determine the exact solubility rates in particular solvents.

Interesting facts

Exploring 2-[(1-methyl-2-phenyl-ethyl)amino]-2-phenyl-acetonitrile

2-[(1-methyl-2-phenyl-ethyl)amino]-2-phenyl-acetonitrile, often abbreviated as a complex compound, holds significant interest in the realm of medicinal chemistry and pharmacology. This compound showcases a unique molecular architecture that combines both aromatic and aliphatic elements, leading to diverse biological activities.

Key Features:

  • Pharmacological Potential: Due to its structural complexity, this compound exhibits potential as a drug candidate, particularly in targeting specific receptor sites in the human body.
  • Inhibition Mechanism: Compounds of similar structures have been studied for their role in inhibiting enzymes associated with various diseases, making them valuable in therapeutic contexts.
  • Aromatic Interactions: The presence of phenyl groups enhances the compound's ability to participate in π-π stacking, which may influence its interaction with biological macromolecules.

The compound’s design is a testament to the work of chemists synthesizing small molecules that can navigate the complexities of biological systems. As researchers delve deeper into its properties, the implications for drug discovery and development are promising. Indeed, in the words of a renowned chemist, “The magic of medicinal chemistry lies in bridging the gaps between structure and activity.”

In summary, 2-[(1-methyl-2-phenyl-ethyl)amino]-2-phenyl-acetonitrile serves as a fascinating subject of study, highlighting the elegance of chemical synthesis and the potential for innovation in pharmaceuticals.

Synonyms
Amfetaminil
Amphetaminil
17590-01-1
Amfetaminilum
anfetaminilo
0XU0V77JVE
NSC-67172
N-(alpha-Methylphenethyl)-2-phenylglycinonitrile
DTXSID80864783
DTXCID30813261
241-560-8
Aponeuron
dl-Amphetaminil
AN 1 (pharmaceutical)
Amfetaminil [INN]
AN 1
NSC 67172
((alpha-Methylphenethyl)amino)phenylacetonitrile
2-phenyl-2-(1-phenylpropan-2-ylamino)acetonitrile
ACETONITRILE, ((alpha-METHYLPHENETHYL)AMINO)PHENYL-
Amfetaminil (INN)
Acetonitrile, [(.alpha.-methylphenethyl)amino]phenyl-
Benzeneacetonitrile, .alpha.-[(1-methyl-2-phenylethyl)amino]-
N-(.beta.-Phenylisopropyl)-.alpha.-aminophenylacetonitrile
Amfetaminilo
.alpha.-Phenyl-.alpha.-(1-phenylisopropyl)aminoacetonitrile
Amfetaminilum [INN-Latin]
Amfetaminilo [INN-Spanish]
AN 1 (VAN)
EINECS 241-560-8
UNII-0XU0V77JVE
BRN 2056148
Amphetaminil (Mixture of Diastereomers) (1.0mg/ml in Acetonitrile)
2-((alpha-Methylphenethyl)amino)-2-phenylacetonitril
alpha-Phenyl-alpha-(1-phenylisopropyl)aminoacetonitrile
N-(beta-Phenylisopropyl)-alpha-aminophenylacetonitrile
alpha-Phenyl-alpha(beta-phenylisopropylamino)acetonitrile
alpha-Phenyl-alpha-N-(1-phenylisopropyl)aminoacetonitrile
alpha-Phenyl-alpha-(1-methyl-2-phenyl)ethylaminoacetonitrile
Benzeneacetonitrile, alpha-((1-methyl-2-phenylethyl)amino)-
AMPHETAMINIL [MI]
AMFETAMINIL [MART.]
NCIOpen2_003034
AMFETAMINIL [WHO-DD]
SCHEMBL160285
CHEMBL2104064
AN 1 (TN)
CHEBI:135022
NSC67172
CS-0026237
NS00002441
D07446
[(.alpha.-Methylphenethyl)amino]phenylacetonitrile
Q474630
N-(.alpha.-Methylphenethyl)-2-phenylglycinonitrile
[(1-Methyl-2-phenylethyl)amino](phenyl)acetonitrile #
.alpha.-Phenyl-.alpha.(.beta.-phenylisopropylamino)acetonitrile
.alpha.-Phenyl-.alpha.-N-(1-phenylisopropyl)aminoacetonitrile
.alpha.-Phenyl-.alpha.-(1-methyl-2-phenyl)ethylaminoacetonitrile