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Metoprolol

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Identification
Molecular formula
C15H25NO3
CAS number
37350-58-6
IUPAC name
2-[(1-methyl-2-phenylsulfanyl-ethyl)amino]ethanol
State
State

At room temperature, Metoprolol is in a solid state, usually available as a powder that is processed into tablets. It maintains its structure under standard conditions of temperature and pressure.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
354.00
Boiling point (Kelvin)
627.15
General information
Molecular weight
267.36g/mol
Molar mass
267.3630g/mol
Density
1.0800g/cm3
Appearence

Metoprolol is typically a white to off-white crystalline powder. It is characterized by its lack of odor. The powder may form small crystals and is often formulated into solid forms such as tablets for medical use.

Comment on solubility

Solubility of 2-[(1-methyl-2-phenylsulfanyl-ethyl)amino]ethanol

The solubility characteristics of 2-[(1-methyl-2-phenylsulfanyl-ethyl)amino]ethanol can be quite intriguing due to its unique molecular structure. This compound exhibits:

  • Moderate Solubility in Water: The presence of the amino group (-NH2) in the molecule enhances its solubility in polar solvents such as water. Amines typically form hydrogen bonds with water, facilitating solvation.
  • Good Solubility in Organic Solvents: Its lipophilic aromatic structure combined with the hydrophilic amino group promotes solubility in a variety of organic solvents, such as ethanol and methanol.
  • pH Dependence: The solubility can vary with changes in pH. Under acidic conditions, protonation of the amino group may improve its solubility in aqueous environments.

It is also important to note that temperature can influence solubility:

  • Higher temperatures often increase solubility of solid compounds in liquids.
  • However, certain interactions within the molecular structure may also affect this relationship.

In summary, 2-[(1-methyl-2-phenylsulfanyl-ethyl)amino]ethanol demonstrates a balance of hydrophilic and lipophilic properties, aligning its solubility with both water and organic solvents, thereby making it a versatile compound in various chemical applications.

Interesting facts

Insights Into 2-[(1-methyl-2-phenylsulfanyl-ethyl)amino]ethanol

2-[(1-methyl-2-phenylsulfanyl-ethyl)amino]ethanol, commonly referred to as a derivative of amino alcohols, is a fascinating compound that showcases the intricate interplay between structure and function in organic chemistry. Here are some engaging details you might find interesting:

  • Applications: This compound has potential applications in medicinal chemistry, particularly in the development of new pharmaceuticals. Its unique structure may contribute to the design of drugs that can interact with biological systems in novel ways.
  • Sulfanyl Group: The presence of the phenylsulfanyl group in its structure offers unique properties that can influence biological activity. Sulfanyl groups are often involved in redox reactions and can serve as important functional moieties in drug design.
  • Amino Alcohols: As a member of the amino alcohol class, it can participate in a range of chemical reactions. This includes acting as a nucleophile in substitution reactions, highlighting its versatility in organic synthesis.
  • Structure-Activity Relationship: Investigating this compound can provide insights into the structure-activity relationship (SAR) of similar compounds. Understanding how small changes in its structure affect biological activity is crucial in pharmacology.
  • Research Potential: Ongoing research into related compounds may uncover new therapeutic avenues, especially in treating various diseases where inhibition or modification of biological pathways is beneficial.

As emphasized by chemists, "The beauty of chemistry lies in its connectivity," which is perfectly exemplified in compounds like 2-[(1-methyl-2-phenylsulfanyl-ethyl)amino]ethanol. This molecule not only highlights the elegance of organic structure but also opens the door for future discoveries in synthetic and medicinal chemistry.

Synonyms
5877-16-7
2-((1-Methyl-2-(phenylthio)ethyl)amino)ethanol
Diethylamine, 2'-hydroxy-1-methyl-2-phenylthio-
Ethanol, 2-[[1-methyl-2-(phenylthio)ethyl]amino]-
ETHANOL, 2-((1-METHYL-2-(PHENYLTHIO)ETHYL)AMINO)-
2-[[1-Methyl-2-(phenylthio)ethyl]amino]ethanol
NSC 220064
BRN 3050471
NSC220064
WLN: Q2MY1&1SR
4-06-00-01552 (Beilstein Handbook Reference)
NSC-220064