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Benztropine

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Identification
Molecular formula
C21H25NO
CAS number
86-13-5
IUPAC name
2-[(1-methyl-2-piperidyl)methoxy]-7-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,9,11,13-heptaene
State
State

Benztropine is typically found in a solid state at room temperature. It is commonly used in the pharmaceutical industry in powdered form or compounded into tablets and other solid dosage forms for medicinal use.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
466.80
Boiling point (Kelvin)
739.95
General information
Molecular weight
307.42g/mol
Molar mass
307.4240g/mol
Density
1.1300g/cm3
Appearence

Benztropine appears as a white crystalline powder. It is relatively stable under normal conditions and should be handled carefully to maintain its purity and effectiveness. The fine powder can clump together, but it remains powdery and granular when handled appropriately.

Comment on solubility

Solubility of 2-[(1-methyl-2-piperidyl)methoxy]-7-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,9,11,13-heptaene

The solubility of the compound 2-[(1-methyl-2-piperidyl)methoxy]-7-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,9,11,13-heptaene is a critical property that influences its behavior in various environments. Understanding this aspect can aid in predicting the compound's applications and interactions. Here are some key points to consider:

  • Solvent Compatibility: The solubility largely depends on the solvent used. Common solvents include water, ethanol, and dimethyl sulfoxide (DMSO). For organic compounds, apolar solvents may be more effective.
  • Temperature Influence: Solubility typically increases with temperature. Therefore, measuring solubility at different temperatures can provide insight into its behavior under varying conditions.
  • Structural Factors: The presence of polar groups or functional moieties can enhance solubility in polar solvents. In this specific compound, the methoxy and piperidyl groups play significant roles in solubilizing the overall structure.
  • pH Dependence: Ionization can affect solubility, particularly for basic or acidic compounds. An assessment of how the compound reacts to different pH levels will provide valuable information regarding its solubility profile.

In summary, thorough solubility testing is essential for understanding the interactions and potential applications of 2-[(1-methyl-2-piperidyl)methoxy]-7-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,9,11,13-heptaene. Predicting its behavior in various solvents and conditions can unlock its vast potential in chemical science.

Interesting facts

Interesting Facts about 2-[(1-methyl-2-piperidyl)methoxy]-7-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,9,11,13-heptaene

This intricate compound belongs to a class of molecules known for their significant pharmacological properties. Notably, it's a derivative of the piperidine family, which is widely studied in medicinal chemistry.

Key Highlights

  • Pharmacological Relevance: This compound’s unique structure suggests potential interactions with biological systems, making it an interesting candidate for drug development.
  • Complex Structure: The compound features a tricyclic structure, indicating a complex array of potential stereoisomers which can contribute to varying biological activities.
  • heteroatoms Inclusion: The presence of nitrogen within its framework (as indicated by 'azatricyclo') contributes to its basicity and affects how it interacts with biological targets.
  • Potential Applications: Compounds of this nature have been investigated for CNS (Central Nervous System) activities, which may open avenues for new therapeutic strategies.

Research Implications

As with many compounds containing the piperidine ring, understanding the relationship between structure and activity is crucial. Research in this area often employs techniques such as:

  • Bioassays to determine the efficacy of the compound in relevant biological models.
  • Structure-activity relationship (SAR) analysis to explore modifications to enhance selectivity and potency.
  • Computational modeling to predict interactions with various biological receptors.

In summary, the compound 2-[(1-methyl-2-piperidyl)methoxy]-7-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,9,11,13-heptaene exemplifies the fascinating intersection of organic chemistry and pharmacology, offering numerous potential pathways for research and development.

Synonyms
BRN 1493557
19410-15-2
5-((1-Methylpiperid-2-yl)methoxy)-5H-benzo(4,5)cyclohepta(1,2-b)pyridine
5-21-04-00109 (Beilstein Handbook Reference)
5H-BENZO(4,5)CYCLOHEPTA(1,2-b)PYRIDINE, 5-((1-METHYLPIPERID-2-YL)METHOXY)-
RefChem:305298
DTXSID40941125
5-[(1-Methylpiperidin-2-yl)methoxy]-5H-benzo[4,5]cyclohepta[1,2-b]pyridine