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N-Methyltryptamine

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Identification
Molecular formula
C11H14N2
CAS number
61-50-7
IUPAC name
2-(1-methylindol-3-yl)ethanamine
State
State

At room temperature, N-Methyltryptamine is typically a solid. It can be found in the form of crystals which makes it easy to handle in laboratory settings.

Melting point (Celsius)
43.26
Melting point (Kelvin)
316.41
Boiling point (Celsius)
273.86
Boiling point (Kelvin)
547.01
General information
Molecular weight
174.26g/mol
Molar mass
174.2550g/mol
Density
1.2000g/cm3
Appearence

N-Methyltryptamine is typically seen as a crystalline solid. It can appear in various shades ranging from white to light brown depending on purity and form.

Comment on solubility

Solubility of 2-(1-methylindol-3-yl)ethanamine

The solubility of 2-(1-methylindol-3-yl)ethanamine in various solvents is an essential aspect to consider in both laboratory and practical applications. This compound is a substituted amine with an indole moiety, which significantly influences its solubility properties. Here are some key points regarding its solubility:

  • Polar solvents: This compound tends to exhibit higher solubility in polar solvents such as water and methanol due to the presence of the amine group. The ability to form hydrogen bonds with polar solvent molecules enhances its solubility.
  • Non-polar solvents: While 2-(1-methylindol-3-yl)ethanamine may show some solubility in non-polar solvents like hexane or chloroform, it is typically much lower compared to polar solvents due to the non-polar nature of the solvent itself.
  • Temperature effect: As with many compounds, increased temperature often results in improved solubility. Thus, dissolving the compound in hot solvents may facilitate its complete dissolution.
  • pH dependence: The solubility can also be affected by the pH of the solution, as the amine can exist in protonated forms at lower pH levels, increasing its solubility in aqueous media.

In summary, the solubility of 2-(1-methylindol-3-yl)ethanamine is quite interactive and depends on multiple factors, which makes it essential to consider the choice of solvent in practical applications.
Understanding these solubility properties can lead to improved handling and utilization of this compound in various chemical processes.

Interesting facts

Interesting Facts about 2-(1-methylindol-3-yl)ethanamine

2-(1-methylindol-3-yl)ethanamine, commonly referred to as Indoleethylamine, is a fascinating compound with intriguing characteristics and applications:

  • Structural Significance: This compound features an indole ring, which is known for its presence in many biologically active compounds and natural products. The indole structure is believed to contribute to the molecule's unique chemical properties.
  • Biological Relevance: Indole derivatives, including this compound, are often studied in relation to their roles in neurotransmission. They are thought to interact with various receptors in the brain, making them of interest in neurochemical research.
  • Synthesis Pathways: The synthesis of 2-(1-methylindol-3-yl)ethanamine can involve multi-step chemical reactions, typically incorporating indole derivatives, amines, and various reagents. Exploring these methods can enhance one’s understanding of synthetic organic chemistry.
  • Potential Applications: Given its structural framework, 2-(1-methylindol-3-yl)ethanamine may have applications in pharmacology, potentially serving as a template for developing new medications associated with mood disorders and psychoactive effects.
  • Research Opportunities: This compound opens up a myriad of research avenues, particularly in the fields of medicinal chemistry, pharmacology, and neurochemistry. Scientists continue to investigate its properties, effects, and potential therapeutic uses.

In conclusion, 2-(1-methylindol-3-yl)ethanamine stands as a compelling subject for anyone fascinated by the intersection of chemistry and biology. Its structural elegance and potential impacts in neuroscience make it a noteworthy compound in modern chemical research.

Synonyms
7518-21-0
1-METHYLTRYPTAMINE
1-Methyl-1H-indole-3-ethylamine
EINECS 231-377-1
231-377-1
2-(1-methyl-1H-indol-3-yl)ethanamine
2-(1-methylindol-3-yl)ethanamine
1H-Indole-3-ethanamine,1-methyl-
2-(1-METHYL-1H-INDOL-3-YL)ETHAN-1-AMINE
3-(2-AMINOETHYL)-1-METHYLINDOLE
CHEMBL3330641
1-Methyltryptamine, free base
N-Methylisotryptamine
a-methyltryptamine
1H-Indole-2-ethanamine, 1-methyl-
BRN 0473426
Tryptamine, 1-methyl-
N-?-METHYLTRYPTAMINE
Oprea1_757922
SCHEMBL332959
DTXSID80991164
CHEBI:125627
2-(1-methyl-3-indolyl)ethanamine
BBL036339
BDBM50025215
MFCD00057093
STK367793
VT1228
AKOS000276207
FM52291
MB00487
1-Methyltryptamine, >=95.0% (GC)
1-METHYL-1H-INDOLE-3-ETHANAMINE
2-(1-methyl-1H-indol-3-yl)ethylamine
2-(1-methyl-1H-indol-3-yl)-ethylamine
AS-54752
NS00047653
EN300-139143
M-4645
5-22-10-00042 (Beilstein Handbook Reference)
AE-848/30742009
2-(1-METHYL-1H-INDOL-3-YL)-1-ETHANAMINE
BRD-K74773935-001-01-6
Q27216239
F2106-0181
55FC1B01-ABF5-490D-A277-3CF781E25C03
1ES