Naproxen | Solubility of Things

Identification

Molecular formula

C₁₄H₁₄O₃

CAS number

22204-53-1

IUPAC name

2-(1-naphthyl)-3-(2-pyridyl)propanoic acid

State

At room temperature, Naproxen is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)

152.00

Melting point (Kelvin)

425.15

Boiling point (Celsius)

434.50

Boiling point (Kelvin)

707.65

General information

Molecular weight

230.26g/mol

Molar mass

230.2590g/mol

Density

1.2122g/cm³

Appearence

Naproxen typically appears as a white to off-white crystalline powder. It is practically odorless, and it may have a slightly bitter taste.

Comment on solubility

Solubility of 2-(1-naphthyl)-3-(2-pyridyl)propanoic Acid

The solubility of 2-(1-naphthyl)-3-(2-pyridyl)propanoic acid is a significant property that influences its application in various chemical and pharmaceutical contexts. Generally, this compound displays variable solubility in different solvents. Here are some key points to consider:

Polar solvents: This compound tends to exhibit limited solubility in water due to its large aromatic naphthyl and pyridyl groups which do not favor hydrogen bonding.
Non-polar solvents: It is known to be more soluble in organic solvents like ethanol and dichloromethane, which can help in its extraction and utilization in synthetic processes.
Temperature effects: Like many organic compounds, temperature can play a crucial role in solubility; increasing temperature typically enhances solubility in organic solvents.

Understanding the solubility of this compound is essential for effectively designing experiments and formulating products. As the saying goes, "like dissolves like," so selecting the appropriate solvent can substantially impact its behavior and functionality in various applications.

Interesting facts

Interesting Facts about 2-(1-naphthyl)-3-(2-pyridyl)propanoic Acid

2-(1-naphthyl)-3-(2-pyridyl)propanoic acid, often referred to by its shorthand as ANP, is a compound that displays fascinating characteristics and applications in the field of chemistry. Below are some intriguing points that highlight its significance:

Unique Structure: This compound features a complex structure that includes both a naphthyl group and a pyridyl group, making it a prominent subject of study in organic chemistry.
Applications in Pharmaceuticals: The unique functional groups within ANP contribute to its pharmacological properties, opening doors for its potential use in drug development.
Bioactivity: Studies have indicated that compounds like ANP can exhibit anti-inflammatory and analgesic properties, which are particularly important for medicinal chemistry.
Synthesis Techniques: The compound can be synthesized through various organic reactions such as Friedel-Crafts acylation, showcasing creative approaches in synthetic organic chemistry.
Research Implications: ANP has proven to be a valuable tool in various research studies involving receptor activity, helping scientists to better understand complex biological interactions.

As the field of chemistry continues to evolve, compounds like 2-(1-naphthyl)-3-(2-pyridyl)propanoic acid remind us of the intricate connections between molecular structure and biological function. As one researcher aptly noted, "The beauty of chemistry lies in its ability to connect seemingly disparate worlds through the tiniest of molecules."

This compound not only captivates the imagination of students and researchers alike but also stands as a testament to the vast potential that lies within the realm of organic compounds.