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Nisoxetine

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Identification
Molecular formula
C22H30N2
CAS number
53179-07-8
IUPAC name
2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanenitrile
State
State

At room temperature, nisoxetine is in a solid state. It is not volatile and remains stable under standard laboratory conditions, maintaining its integrity when stored properly.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
417.40
Boiling point (Kelvin)
690.55
General information
Molecular weight
338.49g/mol
Molar mass
348.4900g/mol
Density
1.0700g/cm3
Appearence

Nisoxetine is typically found as a crystalline solid. It usually presents as a white to off-white powder, which is generally odorless and exhibits consistent texture.

Comment on solubility

Solubility of 2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanenitrile

The solubility of the compound 2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanenitrile is an intriguing topic due to its complex structure and characteristics. Generally, the solubility of such compounds can depend on several factors:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, while non-polar characteristics may lead to better solubility in non-polar solvents.
  • Hydrogen Bonding: If the compound can form hydrogen bonds, it may exhibit higher solubility in water, which is a polar solvent.
  • Molecular Size: Larger molecules tend to have decreased solubility due to steric hindrance and reduced ability to interact favorably with solvents.
  • Temperature: Increasing the temperature often enhances the solubility of solids in liquids. Hence, the solubility may vary with temperature changes.

Based on its structure, this compound may present limited solubility in aqueous media but could exhibit better solubility in organic solvents such as ethanol or dichloromethane.

It's also notable to mention that, as with many organic molecules, the solubility can be experimentally determined and may vary with different factors in a laboratory setting. The importance of solubility lies not only in formulation but also in understanding its pharmacological properties.

Interesting facts

Interesting Facts about 2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanenitrile

This unique compound is a fascinating example of organic chemistry due to its complex structure and potential applications. Here are some intriguing points about this compound:

  • Structural Complexity: The compound features a naphthalene moiety, which is known for its versatile chemical properties and use in various industrial applications.
  • Pharmacological Potential: Compounds similar to this structure often exhibit biological activity, making them of great interest in the field of medicinal chemistry. Studies have suggested potential uses in treating neurological conditions.
  • Derivatives and Analogues: As a derivative of butanenitrile, this compound can serve as a foundation for synthesizing numerous analogues with varied properties and functions. Such modifications can lead to enhanced efficacy or reduced side effects in pharmaceutical applications.
  • Interactions with Receptors: The presence of the piperidyl moiety suggests potential interactions with neurotransmitter receptors, which might be crucial for developing new therapeutic agents targeting the central nervous system.
  • Research Opportunities: Given its complexity, this compound offers a rich area for research into synthesis methods, structure-activity relationships, and potential environmental impacts.

In summary, 2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanenitrile is not just a compound of chemical interest; it also opens up avenues for potential research and therapeutic applications that could benefit various scientific fields.

Synonyms
BRN 1356055
1-NAPHTHALENEACETONITRILE, alpha,alpha-BIS(2-PIPERIDINOETHYL)-
DTXSID70183955
2982-07-2
alpha,alpha-Bis(2-piperidinoethyl)-1-naphthaleneacetonitrile
DTXCID10106446
5-20-03-00317 (beilstein handbook reference)