Skip to main content

Nefopam

ADVERTISEMENT
Identification
Molecular formula
C21H29NO2
CAS number
13669-70-0
IUPAC name
2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanoic acid
State
State

At room temperature, nefopam usually exists in a solid state. It is stable under ordinary conditions of use and storage.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
475.20
Boiling point (Kelvin)
748.35
General information
Molecular weight
325.47g/mol
Molar mass
325.4570g/mol
Density
1.1614g/cm3
Appearence

Nefopam is typically encountered as a white crystalline powder. The compound does not have any distinctive smell and is generally observed as solid granules.

Comment on solubility

Solubility of 2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanoic acid

The solubility of this complex compound, 2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanoic acid, can be influenced by a variety of factors. Here are some key points to consider:

  • Polarity: The presence of the piperidine rings can create a degree of polarity, which may enhance solubility in polar solvents.
  • Functional Groups: The carboxylic acid group is generally hydrophilic and can contribute to solubility in water.
  • Hydrogen Bonding: The possibility of forming hydrogen bonds with solvent molecules can further increase solubility, especially in aqueous environments.
  • Temperature Effects: As with many organic compounds, solubility in various solvents often increases with temperature.
  • Solvent Type: Organic solvents such as ethanol, methanol, or DMSO might dissolve this compound more readily than water.

In summary, while the solubility of 2-(1-naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanoic acid could be expected to exhibit moderate solubility in polar solvents due to its functional groups, specific solubility characteristics are best determined through experimental data. As the saying goes, "solubility is key," emphasizing its importance in chemical reactivity, formulations, and applications.

Interesting facts

Interesting Facts about 2-(1-Naphthyl)-4-(1-piperidyl)-2-[2-(1-piperidyl)ethyl]butanoic acid

This compound, often referred to in the scientific community as a derivative of naphthalene and piperidine, is noteworthy for its complex structure and potential biological activity. Here are some fascinating insights:

  • Structural Complexity: The presence of both naphthyl and piperidyl groups adds a layer of complexity to the molecule, which can influence its reactivity and interaction with biological targets.
  • Drug Development: Compounds like this are of significant interest in medicinal chemistry, owing to their potential applications in developing new therapeutics. They might exhibit activities related to neurotransmitter regulation, making them candidates for studying neurological conditions.
  • Research Applications: Scientists study such compounds to understand the mechanisms of action in biological systems. The unique arrangement of functional groups can affect how the compound interacts with receptors and enzymes.
  • Chirality and Isomerism: Many compounds in this class exhibit chirality, leading to different isomers with distinct biological activities. Understanding these variations is crucial for drug efficacy and safety.
  • Interdisciplinary Interest: This compound draws attention not only from chemists but also from pharmacologists, biochemists, and toxicologists, showcasing the interconnected nature of modern scientific research.

As a student or researcher delving into this area, one could say: "Compounds like this serve as a reminder of the intricate dance between structure and function in the world of organic chemistry." The study of such complex molecules provides a rich tapestry of knowledge and an opportunity to innovate in drug discovery and design.