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AN-162

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Identification
Molecular formula
C19H24N2
CAS number
186992-05-4
IUPAC name
2-(1-naphthyl)-4-(1-piperidyl)butanenitrile
State
State

At room temperature, this compound is typically found in a solid state, possessing a crystalline form that reflects light variably based on its surface quality.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
489.15
Boiling point (Kelvin)
762.30
General information
Molecular weight
291.41g/mol
Molar mass
291.4070g/mol
Density
1.1550g/cm3
Appearence

The compound appears as a solid with varying crystal structures, possibly having a tan or off-white coloration depending on its purity.

Comment on solubility

Solubility of 2-(1-naphthyl)-4-(1-piperidyl)butanenitrile

The solubility of 2-(1-naphthyl)-4-(1-piperidyl)butanenitrile can be characterized by several key factors:

  • Polarity: This compound possesses both hydrophobic (due to the naphthyl and piperidyl groups) and potentially polar functional components (the nitrile group). This dual nature influences its solubility in different solvents.
  • Solvent Interactions: Typically, such compounds show greater solubility in organic solvents like:
    • Ethyl acetate
    • Chloroform
    • Dichloromethane
  • Water Solubility: Due to the naphthyl group’s hydrophobic characteristics, it is expected that this compound has limited solubility in water. This is a common trait among compounds with substantial aromatic structures.

As a result, one might conclude that 2-(1-naphthyl)-4-(1-piperidyl)butanenitrile is insoluble in polar solvents while exhibiting significant solubility in non-polar organic solvents. This behavior underscores the importance of solvent choice when working with such a compound in chemical processes.

Interesting facts

Interesting Facts about 2-(1-naphthyl)-4-(1-piperidyl)butanenitrile

2-(1-naphthyl)-4-(1-piperidyl)butanenitrile is a fascinating compound known for its unique structure and potential applications in medicinal chemistry. Here are some intriguing facts:

  • Structural Diversity: This compound features a naphthyl group, a bicyclic structure consisting of two fused benzene rings, which contributes to its aromatic properties and stability.
  • Pharmacological Potential: The presence of a piperidine ring, known for its ability to act as a basic nitrogen-containing structure, suggests its potential as a candidate for pharmacological activity. Piperidine derivatives are often explored for their role in drug development.
  • Importance in Research: Compounds like 2-(1-naphthyl)-4-(1-piperidyl)butanenitrile have been studied for their interaction with various biological targets, making them crucial in understanding mechanisms of action in pharmacology.
  • Analogous Compounds: This compound is part of a larger class of naphthyl and piperidyl derivatives, many of which have been synthesized to evaluate their efficacy as therapeutic agents in central nervous system disorders.
  • Potential Side Effects: Due to its structural features, it is essential to evaluate the safety and toxicity profile of this compound, as certain aminated compounds can exhibit adverse effects.

As researchers continue to explore the possibilities of this compound, its unique configuration may contribute to innovations in drug design and therapeutic strategies. In the words of a famous chemist, "Chemistry is the science of matter, but the art of chemistry is the creation of new compounds with novel functionalities." With compounds like 2-(1-naphthyl)-4-(1-piperidyl)butanenitrile, we witness the artistry of chemistry in action.

Synonyms
1092-11-1
alpha-(2-Piperidinoethyl)-1-naphthaleneacetonitrile
2-naphthalen-1-yl-4-piperidin-1-ylbutanenitrile
BRN 1349277
1-NAPHTHALENEACETONITRILE, alpha-(2-PIPERIDINOETHYL)-
2-(naphthalen-1-yl)-4-(piperidin-1-yl)butanenitrile
SCHEMBL10568132
DTXSID60911027
MXQCLDABRUMZOD-UHFFFAOYSA-N
2-(1-naphthyl)-4-piperidino-butyronitrile