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Naphthylpiperidine derivative

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Identification
Molecular formula
C31H48Cl2N2O2
CAS number
1033872-32-1
IUPAC name
2-(1-naphthyl)-4-piperidin-1-ium-1-yl-2-(2-piperidin-1-ium-1-ylethyl)butanoic acid;dichloride
State
State

At room temperature, this compound is typically found in a solid state, forming crystalline structures. The solid nature makes it suitable for handling in a laboratory environment, especially when precise measurements are necessary for chemical reactions or further analysis.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
488.42g/mol
Molar mass
488.4200g/mol
Density
0.8500g/cm3
Appearence

The compound typically appears as a white or off-white crystalline powder. Its appearance can vary slightly depending on the specific conditions under which it is synthesized and the purity of the compound.

Comment on solubility

Solubility of 2-(1-naphthyl)-4-piperidin-1-ium-1-yl-2-(2-piperidin-1-ium-1-ylethyl)butanoic acid; dichloride

The solubility of the compound 2-(1-naphthyl)-4-piperidin-1-ium-1-yl-2-(2-piperidin-1-ium-1-ylethyl)butanoic acid; dichloride is influenced by various factors:

  • Polarity: Due to the presence of multiple positively charged piperidin-1-ium groups, this compound tends to be more polar, which typically enhances its solubility in polar solvents.
  • Hydrogen Bonding: The carboxylic acid functional group can engage in hydrogen bonding, further promoting solubility in water and other hydrogen-bonding solvents.
  • Ionic Interactions: As a dichloride salt, the ionic nature of the compound can lead to better solubility in polar solvents, especially in the presence of competing ions.

In general, one can expect this compound to exhibit:

  1. High solubility in water due to its ionic character.
  2. Moderate to high solubility in alcohols and other polar organic solvents.
  3. Limited solubility in non-polar solvents, as its structural components favor interactions with polar environments.

In summary, the solubility of 2-(1-naphthyl)-4-piperidin-1-ium-1-yl-2-(2-piperidin-1-ium-1-ylethyl)butanoic acid; dichloride is significantly enhanced by its polar nature and ability to form hydrogen bonds. Therefore, if you're working with this compound, consider polar solvents for dissolution. As always, experimental data should be consulted for precise solubility measurements in various solvents.

Interesting facts

Interesting Facts about 2-(1-naphthyl)-4-piperidin-1-ium-1-yl-2-(2-piperidin-1-ium-1-ylethyl)butanoic acid; dichloride

This unique compound, which features both naphthalene and piperidine moieties, has drawn attention due to its fascinating structural characteristics and potential applications in medicinal chemistry.

Key Characteristics

  • Complex Structure: The compound comprises multiple piperidine rings, which are known for their ability to interact with various biological targets.
  • Pharmacological Potential: Compounds containing piperidine units often exhibit significant pharmacological activities, including analgesic and CNS effects.
  • Research Applications: This compound may be investigated for its role in treating neurological disorders or its potential as a chemical probe in biological research.

Did You Know?

Compounds like this one can serve as structural scaffolds in drug discovery, allowing scientists to modify specific parts of the molecule to enhance efficacy or reduce side effects. The naphthyl group, in particular, can enhance lipophilicity, aiding in the crossing of cellular membranes.

Quote from the Literature

As noted in a study, "the exploration of naphthalene derivatives reveals their versatility and potential as leads in therapeutic development." This highlights the importance of structural diversity in drug discovery.

The exploration of such compounds demonstrates the exciting intersection of chemistry and pharmacology, offering insights into how modifications in structure can lead to significant changes in biological activity.

Synonyms
alpha,alpha-Bis(2-piperidinoethyl)-1-naphthaleneacetic acid dihydrochloride
1-NAPHTHALENEACETIC ACID, alpha,alpha-BIS(2-PIPERIDINOETHYL)-, DIHYDROCHLORIDE
6376-51-8