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Sertraline

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Identification
Molecular formula
C17H17Cl2N
CAS number
79617-96-2
IUPAC name
2-(1-naphthyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine
State
State

At room temperature, Sertraline is in a solid state, typically distributed as tablets for oral administration.

Melting point (Celsius)
246.00
Melting point (Kelvin)
519.15
Boiling point (Celsius)
301.00
Boiling point (Kelvin)
574.15
General information
Molecular weight
342.70g/mol
Molar mass
342.6970g/mol
Density
1.2220g/cm3
Appearence

Sertraline hydrochloride is typically observed as a white crystalline powder. It is often provided in its tablet form, where it might be combined with other inactive ingredients for stability and ease of administration.

Comment on solubility

Solubility of 2-(1-naphthyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine

The solubility characteristics of 2-(1-naphthyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine (C17H17Cl2N) can be quite fascinating and are influenced by several factors:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, while non-polar structures may favor solubility in organic solvents.
  • Temperature: Solubility generally increases with temperature for most solids, so higher temperatures might increase the solubility of this compound.
  • pH Levels: Since this compound contains nitrogen atoms, altering the pH may influence its solubility by affecting the ionization of the amine functional groups.

In general, compounds of this nature may exhibit:

  • Moderate solubility in organic solvents such as ethanol or dimethyl sulfoxide.
  • Reduced solubility in water, given its significant hydrophobic regions associated with the naphthyl and piperidyl groups.
  • Possible challenges in pharmaceutical formulations due to variable solubility under physiological conditions.

To summarize, the solubility of 2-(1-naphthyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine is influenced by its molecular structure and environmental conditions. A clear understanding of these properties is crucial for its applications within various fields.

Interesting facts

Interesting Facts about 2-(1-naphthyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine

This fascinating compound is a member of the vast family of amines and showcases a blend of unique structural features that give it intriguing properties. Here are some compelling aspects to consider:

  • Complex Structure: The compound’s structure includes a naphthalene moiety, a piperidine ring, and a tetrahydrofuran, which influences its chemical reactivity and biological activity.
  • Potential Applications: Due to the presence of piperidine, compounds of this nature have shown promise in medicinal chemistry, potentially acting as drugs or therapeutic agents in treating neurological disorders.
  • Research Interest: The organic chemistry community is increasingly interested in such structures as they can serve as precursors or derivatives for synthesizing more complex molecules needed in pharmaceuticals.
  • Mechanism of Action: Like many compounds with similar frameworks, it may interact with various neurotransmitter systems, illustrating the significance of structure-activity relationships in drug design.
  • Innovative Synthesis: The synthesis of this compound may involve advanced synthetic strategies that can inspire future research and development in organic synthesis methodologies.

As one delves deeper into the study of 2-(1-naphthyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine, it becomes clear that its intricate design not only provides insight into the realm of organic compounds but also holds potential for impacting real-world applications in the pharmaceutical industry.