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2-(1-Naphthyl)acetamide

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Identification
Molecular formula
C12H11NO
CAS number
86-86-2
IUPAC name
2-(1-naphthyl)acetamide
State
State

At room temperature, 2-(1-Naphthyl)acetamide is in a solid state. It is typically handled in powdered or crystallized form for industrial and laboratory applications.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
409.00
Boiling point (Kelvin)
682.15
General information
Molecular weight
185.22g/mol
Molar mass
185.2170g/mol
Density
1.1974g/cm3
Appearence

2-(1-Naphthyl)acetamide appears as a white to off-white crystalline powder. It is often used in laboratory settings and may exhibit a mild odor. The compound's crystalline nature means it can reflect light, giving it a shiny appearance under certain lighting conditions.

Comment on solubility

Solubility of 2-(1-naphthyl)acetamide

2-(1-naphthyl)acetamide, a compound known for its aromatic structure, exhibits interesting solubility characteristics that can be influenced by various factors. As a member of the amide family, this compound is largely insoluble in water, which can be attributed to its hydrophobic naphthalene moiety. However, it shows good solubility in organic solvents, reflecting the following trends:

  • Solvents Favoring Solubility: It is typically soluble in common organic solvents such as ethanol, acetone, and chloroform.
  • Temperature Dependence: Solubility may increase with temperature, as higher thermal energy can disrupt interactions between molecules, allowing for more effective solvation.
  • pH Influence: The solubility can also be influenced by pH, especially if there are functional groups present that can ionize.

“Understanding solubility is crucial for various applications, including pharmaceutical formulation and environmental chemistry.” Therefore, the solubility profile of 2-(1-naphthyl)acetamide must be considered carefully in related fields, and further studies can provide deeper insights into its behavior in different solvent systems.

Interesting facts

Exploring 2-(1-naphthyl)acetamide

2-(1-naphthyl)acetamide, a fascinating organic compound, belongs to the class of amides and is an important substance in medicinal chemistry. With its interesting structure, this compound consists of a naphthalene ring connected to an acetamide group, which contributes to its unique properties.

Key Features:

  • Pharmacological Importance: The compound has garnered attention for its potential roles in drug design, particularly in the development of anti-inflammatory and analgesic medications.
  • Chemical Reactivity: The acetamide functional group allows for various chemical reactions, making it a versatile building block in organic synthesis.
  • Structure-Activity Relationship: Scientists often study compounds like 2-(1-naphthyl)acetamide to understand how molecular structure influences biological activity and efficacy.
  • Research Applications: Beyond medicinal applications, this compound is also used in the study of lipid membranes, biological systems, and as a starting material for synthesizing other complex molecules.

In the words of researchers, "The exploration of such compounds opens new avenues in therapeutic development." The presence of the naphthalene moiety not only enhances the compound's stability but also impacts its interactions in biological environments. Its relevance in various fields, from pharmacology to materials science, signifies the compound’s versatility and importance.

Overall, 2-(1-naphthyl)acetamide serves as an exemplary model for understanding the interplay between structure and function in chemical compounds, illustrating the profound impact of molecular design in the journey of discovering new drugs and materials.

Synonyms
1-NAPHTHALENEACETAMIDE
86-86-2
1-Naphthylacetamide
Naphthaleneacetamide
2-(1-Naphthyl)acetamide
Frufix
Amid-Thin
Dirigol N
2-(naphthalen-1-yl)acetamide
Amid-Thin W
alpha-Naphthylacetamide
1-Naphthalene acetamide
NAAm
alpha-NAA amide
alpha-Naphthaleneacetamide
2-naphthalen-1-ylacetamide
1-Naphthylamine, N-acetyl-
1-Naphthyl acetamide
.alpha.-Naphthaleneacetamide
alpha-Naphthaleneacetic acid amide
Caswell No. 588
.alpha.-Naphthylacetamide
31093-43-3
Amid kyseliny 1-naftyloctove
NSC 34862
Rosetone
Dirigol-N
EINECS 201-704-2
MFCD00004047
Amid kyseliny 1-naftyloctove [Czech]
2-(1-Naphthyl)acetamide [BSI:ISO]
EPA Pesticide Chemical Code 056001
Naphthalene acetamide
BRN 1945547
11KAX3RJ28
DTXSID3020914
CHEBI:81810
AI3-52514
2(1-Naphthyl)acetamide
NSC-34862
.ALPHA.-NAA AMIDE
DTXCID30914
4-09-00-02426 (Beilstein Handbook Reference)
.alpha.-Naphthaleneacetic acid amide
NAPHTHYL)ACETAMIDE, 2-(1-
(Naphthalen-1-yl)acetamide (1-Naphthylacetamide)
Naamide
1-Naphthyl-acetamide
UNII-11KAX3RJ28
1-Naphthaleneacetamide; (Naphthalen-1-yl)acetamide; 1-Naphthylacetamide
a-Naphthaleneacetamide
alpha-naphthalene acetamide
2-(1-naphthyl)ethanamide
SCHEMBL66670
WLN: L66J B1VZ
2-(1-Naphthyl)acetamide, ISO
CHEMBL3186653
XFNJVKMNNVCYEK-UHFFFAOYSA-
NSC34862
Tox21_200049
AKOS003421730
AC-5791
CS-W023166
FS-3193
CAS-86-86-2
NCGC00164051-01
NCGC00164051-02
NCGC00257603-01
FN140351
SY021125
DB-010854
N0624
NS00006557
C18533
D70476
1-Naphthyl acetamide 100 microg/mL in Acetonitrile
Q4545795
1-Naphthylacetamide, PESTANAL(R), analytical standard
201-704-2
InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)