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Naphazoline nitrate

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Identification
Molecular formula
C14H15N3O3
CAS number
550-99-2
IUPAC name
2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazol-1-ium;nitrate
State
State

At room temperature, Naphazoline nitrate is a solid. It is commonly available in the form of a crystalline powder which can be used in various pharmaceutical applications due to its vasoconstrictor properties.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
294.33g/mol
Molar mass
294.3270g/mol
Density
0.8547g/cm3
Appearence

Naphazoline nitrate appears as a white to yellowish crystalline powder and is often characterized by its fine granules. This compound can be slightly hygroscopic, meaning that it may gradually absorb moisture from the air, potentially leading to clumping or changes in its physical state if not stored properly.

Comment on solubility

Solubility of 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazol-1-ium Nitrate

The solubility of 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazol-1-ium nitrate can be influenced by several factors, including its chemical structure and the nature of the solvent used. Key points regarding its solubility include:

  • Polar vs. Nonpolar Solvent: This compound contains polar functional groups due to the imidazolium ion and nitrate, which may enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of hydrogen bonding capabilities could promote solvation in suitable solvents, leading to increased solubility.
  • Temperature Effects: Solubility often increases with temperature. Thus, conducting solubility tests at elevated temperatures may reveal greater solubility rates.
  • Concentration Limits: In saturated solutions, the compound may demonstrate a threshold beyond which no further solvation occurs.

As noted, the solubility profile of this compound may vary:

  • It may exhibit **high solubility** in water due to ionic interactions.
  • In organic solvents, **compatibility** with the solvent's polarity will determine the degree of solubility.

In summary, understanding the solubility of 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazol-1-ium nitrate is crucial for its application in various chemical processes. Remember, "solubility is the key to reactivity!"

Interesting facts

Interesting Facts about 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazol-1-ium Nitrate

The compound 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazol-1-ium nitrate represents a fascinating class of organic compounds known for their extensive applications in various fields, including medicinal chemistry and materials science.

Structural Highlights

Characterized by a complex structure, this compound includes:

  • Imidazolium core: This heterocyclic structure is notable for its stability and rich chemistry, often participating in various chemical reactions.
  • Naphthylmethyl group: The presence of this aromatic group contributes to the compound's unique properties, enhancing its interactions with biological targets.

Applications in Research

Due to its intriguing properties, this compound finds numerous applications, including:

  • Catalysis: The imidazolium cation is a pivotal component in many catalytic processes, especially in organic transformations.
  • Medicinal Chemistry: Research has explored its potential uses in drug development, particularly in targeting various biological pathways.
  • Material Science: The compound may also find applications in the synthesis of new materials with unique optical and electronic properties.

Biological Significance

One area of interest among scientists is the biological activity of imidazolium-based compounds. Some relevant points include:

  • The ability to interact with biological systems due to their polar and nonpolar regions.
  • Potential as anti-cancer agents due to their mechanism of action that targets specific cellular pathways.

As we explore the vast landscape of chemical compounds, the study of 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazol-1-ium nitrate opens up numerous avenues for research, promising exciting advancements in both chemical science and practical applications.

Synonyms
4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazolium nitrate
10061-11-7
2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazol-1-ium;nitrate
NS00082891