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Nefiracetam

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Identification
Molecular formula
C14H18N2O2
CAS number
77191-36-7
IUPAC name
2-(1-naphthylmethyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine
State
State

At room temperature, Nefiracetam is in a solid state.

Melting point (Celsius)
99.80
Melting point (Kelvin)
372.90
Boiling point (Celsius)
351.20
Boiling point (Kelvin)
624.40
General information
Molecular weight
239.28g/mol
Molar mass
239.2820g/mol
Density
1.2200g/cm3
Appearence

Nefiracetam is typically available as a pale yellow or white powder. It is crystalline in nature and often used in the form of tablets or capsules for medicinal purposes.

Comment on solubility

Solubility Characteristics

The compound 2-(1-naphthylmethyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine, represented by the formula C14H18N2O2, exhibits a complex solubility profile that can be influenced by various factors.

Influencing Factors:

  • Polarity: The presence of a tetrahydrofuran ring and amine functional groups enhances its polarity, potentially increasing solubility in polar solvents.
  • Hydrophobic Interactions: The naphthylmethyl group contributes significant hydrophobic character, which may limit solubility in highly polar solvents while increasing it in organic solvents.
  • pH Levels: The ionization state of the amine group can change based on pH, affecting solubility in aqueous solutions.

In general, the solubility of this compound can be categorized as follows:

  • Aqueous Solutions: Likely limited due to hydrophobic parts, but some solubility may occur, especially in acidic conditions where the amine becomes protonated.
  • Organic Solvents: More soluble in less polar organic solvents such as dichloromethane or ether, which can accommodate the hydrophobic regions.

As with many complex organic molecules, empirical testing is recommended to determine precise solubility characteristics, as theoretical predictions may not always align with observed behavior. Experimentation can help reveal the nuances of solubility for such compounds, guiding effective applications.

Interesting facts

Interesting Facts about 2-(1-naphthylmethyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine

This compound, characterized by its complex structure, falls under the category of biologically active molecules. It is particularly noteworthy for its potential applications in the field of pharmacology. Here are some key points of interest:

  • Diverse Structural Features: The compound features a unique combination of a tetrahydrofuran ring along with naphthyl and piperidyl moieties, making it a fascinating subject for the study of synthetic and medicinal chemistry.
  • Potential Pharmacological Effects: Compounds with similar structures have been researched for their effects on the central nervous system. This raises intriguing possibilities for its use in treating various neurological conditions.
  • Origin of Its Components: The naphthyl group is often associated with organic compounds that display significant biological activity, including antimicrobial and anticancer properties.
  • Functionalization: The ability to manipulate the functional groups of this compound opens avenues for creating derivatives that could enhance its activity or selectivity.
  • Pharmaceutical Synthesis: Chemists might find this compound to be a candidate for innovative methods of synthesis, allowing the examination of reaction pathways and mechanisms in detail.

In summary, 2-(1-naphthylmethyl)-N-[2-(1-piperidyl)ethyl]-3-tetrahydrofuran-2-yl-propan-1-amine is a compound that embodies the intersection of complex organic chemistry and pharmacological potential. Its study could pave the way for improved therapeutic agents in clinical settings.