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Naphthylpyrovalerone

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Identification
Molecular formula
C21H29NO2
CAS number
850352-53-3
IUPAC name
2-(1-naphthylmethyl)-N-(2-pyrrolidin-1-ylethyl)-3-tetrahydrofuran-2-yl-propan-1-amine
State
State

At room temperature, Naphthylpyrovalerone exists in a solid state. It is a crystalline compound that remains stable under standard room conditions, without decomposing or reacting with atmospheric moisture.

Melting point (Celsius)
147.30
Melting point (Kelvin)
420.45
Boiling point (Celsius)
543.50
Boiling point (Kelvin)
816.65
General information
Molecular weight
323.44g/mol
Molar mass
323.4420g/mol
Density
1.1520g/cm3
Appearence

Naphthylpyrovalerone is typically found as a white crystalline powder. It is known for its high purity form when synthesized, appearing as fine crystals that can easily dissolve to form a clear solution in organic solvents.

Comment on solubility

Solubility of 2-(1-naphthylmethyl)-N-(2-pyrrolidin-1-ylethyl)-3-tetrahydrofuran-2-yl-propan-1-amine (C21H29NO2)

The solubility of the compound 2-(1-naphthylmethyl)-N-(2-pyrrolidin-1-ylethyl)-3-tetrahydrofuran-2-yl-propan-1-amine is influenced by its complex structure. This compound features a multi-ring system and amine functionalities, which can lead to varied solubility profiles depending on the solvent used.

Key factors affecting solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, such as water or alcohols.
  • Hydrophobic regions: The naphthalene moiety contributes to hydrophobic characteristics, potentially lowering solubility in aqueous solutions.
  • Molecular interactions: Hydrogen bonding capabilities can facilitate solubility in certain organic solvents, which can compensate for limitations in water solubility.

Typically, compounds with such complex structures show limited solubility in water but may dissolve in organic solvents like ethanol or dimethyl sulfoxide (DMSO). Observations suggest that solubility might range from low to moderate in aqueous environments, thereby necessitating consideration of solvent choice in applications. As such, it's crucial to explore various environments to determine optimal solubility conditions for this compound.

In summary, while the complex structural features of C21H29NO2 may hinder its solubility in water, other solvents could facilitate its application in diverse chemical settings, emphasizing the importance of a tailored approach to solubility analysis.

Interesting facts

Interesting Facts about 2-(1-naphthylmethyl)-N-(2-pyrrolidin-1-ylethyl)-3-tetrahydrofuran-2-yl-propan-1-amine

This compound, a fascinating example of an organic amine, presents a unique structure that combines multiple functional groups, which significantly influences its properties and potential applications.

Structural Characteristics

  • Complexity: The compound features a tetrahydrofuran moiety, a 1-naphthyl group, and an amine functional group, indicating its complexity and potential for a variety of reactivity.
  • Rigidity and Flexibility: The presence of both rigid (naphthyl) and flexible (pyrrolidinyl) segments allows for a diverse range of conformations, which is crucial in drug design.

Potential Applications

  • Pharmaceutical Significance: Compounds of this nature can exhibit properties beneficial for drug development, especially in creating novel therapeutic agents.
  • Research in Neuroscience: Due to the amine and pyrrolidine groups, it may interact with neurotransmitter systems, making it of interest in neurological studies.

Scientific Insights

As researchers delve deeper into compounds like this, they often find that subtle changes in structure can lead to significant variations in biological activity. As noted by many chemists, "The magic of organic chemistry lies in its complexity and the myriad ways simple molecules can be transformed into elaborate architectures." This principle certainly applies to our compound, which embodies the intricate dance of molecular interactions.


Overall, the study of 2-(1-naphthylmethyl)-N-(2-pyrrolidin-1-ylethyl)-3-tetrahydrofuran-2-yl-propan-1-amine opens doors to exploring innovative chemical properties and potential therapeutic benefits, making it an exciting subject for both chemists and pharmacologists alike.