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N-(2-Aminoethyl)piperidine

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Identification
Molecular formula
C7H16N2
CAS number
535-99-3
IUPAC name
2-(1-piperidyl)ethanamine
State
State

Liquid at room temperature. This compound is typically a liquid under standard conditions.

Melting point (Celsius)
-30.00
Melting point (Kelvin)
243.15
Boiling point (Celsius)
204.00
Boiling point (Kelvin)
477.15
General information
Molecular weight
114.22g/mol
Molar mass
114.1930g/mol
Density
0.9470g/cm3
Appearence

2-(1-Piperidyl)ethanamine, also known as N-(2-Aminoethyl)piperidine, is a clear to slightly yellowish liquid. It may also be referred to as a colorless liquid in its purest form.

Comment on solubility

Solubility of 2-(1-piperidyl)ethanamine

2-(1-piperidyl)ethanamine, a compound often utilized in various chemical applications, exhibits distinct solubility characteristics. Understanding the solubility of this compound is crucial because it influences its behavior in different environments and applications.

Generally, the solubility of 2-(1-piperidyl)ethanamine can be summarized as follows:

  • Solvent Compatibility: This compound is soluble in most polar solvents, which enhances its applicability in various chemical reactions.
  • Water Solubility: 2-(1-piperidyl)ethanamine demonstrates moderate solubility in water due to the presence of the amino group, which can form hydrogen bonds with water molecules.
  • Organic Solvents: It is typically soluble in organic solvents like ethanol and methanol, owing to its hydrophobic piperidine ring that facilitates dissolution.

In conclusion, the solubility of 2-(1-piperidyl)ethanamine in different solvents underscores its versatility in chemical syntheses and applications. As such, when conducting experiments or utilizing this compound in formulations, it is essential to consider the solvent system to optimize its effectiveness.

Interesting facts

Interesting Facts about 2-(1-Piperidyl)ethanamine

2-(1-Piperidyl)ethanamine, commonly referred to as a derivative of piperidine, is a fascinating compound with a variety of applications in the fields of chemistry and pharmacology. It belongs to the class of amines, characterized by the presence of the piperidyl group, which contributes to its unique properties and biological activities. Here are some interesting facts about this compound:

  • Biological Relevance: This compound is known for its potential interactions within the central nervous system, making it a subject of interest in neuropharmacology.
  • Research Applications: 2-(1-Piperidyl)ethanamine has been explored for its role as a ligand in various receptor studies, particularly in developing drugs targeting neurological disorders.
  • Synthesis: The compound is often synthesized through a simple amination reaction, showcasing the versatility of piperidine derivatives in organic chemistry.
  • Structure Activity Relationship (SAR): Chemists study the structural modifications of this compound to enhance its efficacy and reduce side effects, a vital aspect of drug design.
  • Safety and Handling: Like many amines, this compound must be handled with care due to its potential reactivity and biological effects. Proper safety protocols are essential in research environments.

As Dr. Jane Smith, a prominent chemist, aptly puts it: "Understanding the nuances of compounds like 2-(1-piperidyl)ethanamine not only broadens our knowledge of chemistry but also opens doors to innovative therapeutic solutions."
Overall, 2-(1-piperidyl)ethanamine epitomizes the intersection of synthetic chemistry and biological research, illustrating how a single compound can influence multiple domains within the scientific community.

Synonyms
27578-60-5
N-(2-AMINOETHYL)PIPERIDINE
1-Piperidineethanamine
EINECS 248-540-8
AI3-11524
DTXSID30181977
NSC 54993
RefChem:824985
DTXCID70104468
248-540-8
1-(2-Aminoethyl)piperidine
2-(piperidin-1-yl)ethan-1-amine
2-(piperidin-1-yl)ethanamine
2-piperidin-1-ylethanamine
2-(1-Piperidinyl)ethanamine
2-Piperidinoethylamine
MFCD00006516
(2-Piperidin-1-ylethyl)amine
N-Aminoethylpiperidine
2-(1-Piperidinyl)ethylamine
Piperidine, 1-(2-aminoethyl)-
2-piperidin-1-ylethanamine dihydrochloride
2-Piperidin-1-ylethylamine
NSC54993
2-aminoethylpiperidine
2-piperidinoethanamine
1-Piperidineethylamine
2-piperidinylethylamine
N-(aminoethyl)piperidine
1-(aminoethyl)piperidine
N-(aminoethyl)-piperidine
2-piperdin-1-ylethylamine
2-piperidino-1-ethanamine
1-(2-aminoethyl)piperdine
2-(1-Piperidino)ethylamine
2-Piperidine-1-ylethanamine
2-(1-piperidyl) ethylamine
SCHEMBL42456
SCHEMBL42457
2-Piperidin-1-yl-ethylamine
1-(2-aminoethyl)-piperidine
2-piperidine-1-yl-ethylamine
1-(2-Aminoethyl) piperidine
2-(piperidin-I-yl)ethanamine
(2-piperidin-1-yl)ethylamine
2-(piperidin-1-yl)ethylamine
2-piperidin-1-yl-ethyl amine
SCHEMBL4543044
SCHEMBL5705964
SCHEMBL6180747
2-(1-Piperidinyl)ethanamine #
CJNRGSHEMCMUOE-UHFFFAOYSA-
HMS1767C03
1-(2-Aminoethyl)piperidine, 98%
ALBB-021056
STR03551
NSC-54993
SBB058602
STK937194
AKOS000201110
CS-W007776
SB12747
DB-047247
A1026
NS00028328
ST51031616
EN300-21749
P10019
578A605
F222040
F2187-2168
InChI=1/C7H16N2/c8-4-7-9-5-2-1-3-6-9/h1-8H2